• The differential approach in the treatment of chronic constipation in children with congenital intestinal development 
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The differential approach in the treatment of chronic constipation in children with congenital intestinal development 

SOVREMENNAYA PEDIATRIYA.2016.8(80):103-110; doi 10.15574/SP.2016.80.103 

The differential approach in the treatment of chronic constipation in children with congenital intestinal development 

Berezhnoi V. V., Kozachuk V. G., Ribalchenko V. F.

Shupik National Medical Academy of Postgraduate Education, Kiev, Ukraine


Objective. To examine clinical efficacy of the «Medulak» preparation in the complex treatment of chronic constipation in children occurred due to the congen!

ital colon abnormality.


Patients and methods. A clinical study included 30 children with chronic constipation occurred due to the congenital colon abnormality. The average age of

the patients was 7,5 ± 2,1 years. The diagnosis was verified according to the basis of medical history, patient complaints, clinical examination, digital exam!

ination of the rectum, laboratory methods, ultrasound scan of the abdominal cavity and ergography. In addition to the complex therapy patients had received

«Medulak» preparation. Monitoring of the effectiveness of the therapy was carried out on the 15th and 30th day of treatment.


Results. According to the results of ergography the signs of dolichocolon were detected in 10 (33.3%) patients, megadolichocolon — in 6 (20%), megacolon —

in 3 (10%), dolichocolon + Payra syndrome — in 3 (10%), megacolon + Payra syndrome — in 2 (6.6%), dolichocolon + megarectum — in 2 (6.6%),

megadolichosigmoids — in one child. Before the treatment in children, along with gastrointestinal disorders were observed dermatointerstitial and vegetative

manifestations. During the follow!up in most children was found a violation of the intestinal microbiota. According to the results of coprological research in

26 (86.7%) children was determined insufficient digestion of proteins, fats and carbohydrates. During the treatment by Medulak the positive clinical dynam!

ics was observed in all patients. On the 15th day of the treatment in half of the patients were absent any clinical symptoms of constipation. The positive clin!

ical effect was found in most of children (93.3%).


Conclusions. The use of «Medulak» in the complex therapy of chronic constipation in children with congenital colon abnormality resulted to the good thera!

peutic efficacy. Preparation improves the character of discharge, helps to stimulate bowel motility, normalizes its microbiocenosis and prevents complica!

tions, that allows to recommend it in the practice of pediatricians, general practitioners — family doctors and pediatric surgeons.


Key words: children, constipation, congenital colon Medulak.


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