• State of uterine blood flow in women of reproductive age with endometrial hyperplasia

State of uterine blood flow in women of reproductive age with endometrial hyperplasia

HEALTH OF WOMAN. 2016.7(113):141–143; doi 10.15574/HW.2016.113.141


State of uterine blood flow in women of reproductive age with endometrial hyperplasia


Dubinina V. G., Vizir K. M.

Odessa national medical University


The objective: to assess the state of uterine blood flow in endometrial hyperplasia in women of reproductive period.


Patients and methods. 130 patients (n=100 – the main group; n=30 – control group) aged 18-49 years with endometrial hyperplasia were examined. All the women underwent 2D transvaginal echography and color Doppler mapping. The angle-independent indices (pulsatility index, resistivity index, diastolic/systolic ratio) of blood flow were determined in the uterine, arcuate, radial, basal and spiral arteries.


Results. There was no significant difference in the indices of blood flow of the right uterine artery, arcuate, radial, basal arteries among patients and control group. Among women with endometrial hyperplasia pulsatility index of the left uterine artery amounted to – 2.11, resistivity index – 0.88, and the diastolic/systolic ratio – 5.45, in women of the control group – 2.34, 1.01 and 7.50, respectively. Only among patients with endometrial hyperplastic process was registered blood flow in the spiral arteries.


Conclusion. The use of color Doppler mapping is appropriate, because registration of intraendometrial blood flow allows an endometrial hyperplastic process to be diagnosed with a high degree of confidence.


Key words: endometrial hyperplasia, reproductive period, color Doppler mapping, intraendometrial blood flow, pulsatility index, resistivity index, diastolic/systolic ratio.


REFERENCES

1. Abdullaev RJ, Grabar VV, Lysenko TP. 2009. Doppler in gynecology. Kharkov, new word:104.

2. Ashrafyan LA, Ivanova SV, Myagkova AA. 2012. The possibilities of ultrasound diagnosis of endometrial cancer. Bulletin of the Russian Scientific Center of Radiology of Russian Ministry of Health 2(3):90-95.

3. Adamyan LV. 2015. Combined benign tumors and hyperplastic processes of the uterus (myoma, adenomyosis, endometrial hyperplasia). Clinical guidelines for the management of patients:92.

4. Hachkuruzov SG. 2012. Ultrasound in Gynecology. Symptoms. Diagnostic difficulties and mistakes. SPb, ELBI-SPb:672.

5. ACOG Practice Bulletin 36: Management of Abnormal uterine bleeding associated with ovulatory dysfunction. 2013. Obstet Gynecol. 122:176-185.

6. Benyuk VA, Kurochka VV, Vynyarskyi YM et al. 2009. Diagnostic algorithm endometrial pathology using hysteroscopy in reproductive age women. Women Health 6(42):54–56.

7. Hannemann MM, Alexander HM, Cope NJ. 2010. Endometrial hyperplasia: a clinician’s review. Obstet Gynecol Reprod Med. 20(4):116-120. http://dx.doi.org/10.1016/j.ogrm.2010.01.002

8. Lacey JVJr, Victoria MC. 2009. Endometrial hyperplasia and the risk of progression to carcinoma. Maturitas. 63:39-44. http://dx.doi.org/10.1016/j.maturitas.2009.02.005; PMid:19285814

9. Ozdemir S, Celik C, Gezginc K et al. 2010. Evalution of endometrial thickness with transvaginal sonography and histopathology in premenopausal women with abnormal vaginal bleeding. Arch Gynecol Obstet. 282:395-399. http://dx.doi.org/10.1007/s00404-009-1290-y; PMid:19921229