• State infants after perinatal complications prevention by mother with the association of HIV and herpes virus infection

State infants after perinatal complications prevention by mother with the association of HIV and herpes virus infection

SOVREMENNAYA PEDIATRIYA.2016.8(80):30-32; doi 10.15574/SP.2016.80.30 

State infants after perinatal complications prevention by mother with the association of HIV and herpes virus infection

Zhdanovich O. I., Anoshyna T. M., Kolomiichenko T. V.

SI Institute of Pediatrics, Obstetrics and Gynecology NAMS Ukraine, Kyiv

Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

Relevance. Complicated and little studied issue is the perinatal complications prevention in pregnant women with HIV and herpes virus infections (GI) The goal — to evaluate the effectiveness of the system of perinatal complications prevention during the association of HIV and herpes infection.

Materials and methods. Selected 60 HIV-infected pregnant women with the GI, which divided into 2 groups: primary — 30 pregnant women with the use of recommended prophylaxis complex (specific immunoglobulins, interferon α-2β, flavonoids, probiotics, arginine glutamat), the comparison group — 30 pregnant women with the knowledge of the pregnancy according to the Ministry of Health reports.

Results. After recommended treatment course significantly improving the condition of children at birth: in satisfactory condition (without asphyxia) was born 60.0 against 37.9% of children (p<0.05). Relatively better and during the period of early neonatal adaptation: 1.5–2 times lower than the frequency of jaundice, hemorrhagic syndrome, and gastrointestinal. Significantly reduces the incidence of life-threatening syndromes and further development of the child as neurological (up 23.3% vs. 44.8%, p<0.05) and RDS (up 16.7% vs. 37.9%, p<0.05).

Conclusions. Security and high efficiency of the proposed complex of perinatal complications prevention for HIV-infected pregnant women with herpes infection can be recommended for implementation in antenatal clinics and maternity homes.

Keywords: fetus, newborn, HIV, herpes virus infection, therapy.


1. Anoshyna TM. 2015. Perinatal outcomes in HIV-infected pregnant women with herpes virus infection. Sovremennaya pedyatriya. 6(70):110-112.

2. HIV infection, secondary and co-morbidities. Ed. NA Belyakov, VV Rassokhin, EV Stepanova. Tematicheskiy arkhiv. 2014. Saint Petersburg, Baltiyskiy meditsinskiy obrazovatel'nyy tsentr: 368.

3. Borak VP, Romaniuk LB, Borak VT, Kravets NIa. 2016. On the herpes infection by topical issue today. Aktualna infektolohiia. 2 (11): 53-58.

4. Isakov VA, Isakov DV. 2014. Pathogenesis and treatment of socially significant viral urogenital infections (herpes and papillomavirus infection). Klin. farmakologiia i terapiia. 23(1): 7-13.

5. Kuz'min VN. 2014. The modern view of the clinical course, diagnosis and treatment of genital herpes in women. Consilium Medicum. 06: 55-60.

6. Yatsenko DS. 2015. The course of pregnancy, childbirth and neonatal status in women with HIV infection. BMIK. 5:448.

7. Nigro G, Adler SP, Parruti G. 2012. Immunoglobulin therapy of fetal cytomegalovirus infection occurring in the first half of pregnancy – a case-control study of the outcome in children. J Infect Dis. 205(2): 215-227. https://doi.org/10.1093/infdis/jir718; PMid:22140265

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