• Сomplex perinatal care in pregnancy at the association of HIV and herpes virus infection
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Сomplex perinatal care in pregnancy at the association of HIV and herpes virus infection

HEALTH OF WOMAN. 2016.10(116):33–36

Сomplex perinatal care in pregnancy at the association of HIV and herpes virus infection

Kaminskiy V. V., Anoshyna T. M., Zhdanovich O. I.

National Medical Academy of Postgraduate Education P. L. Shupyk, Kiev

SI «Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine», Kiev

Complicated and little studied issue is the treatment of herpes virus infections (GI) in pregnant women with HIV.

The objective: to evaluate the effectiveness of the system of perinatal protection of the fetus during the association of HIV and herpes infection.

Patients and methods. Selected 60 HIV-infected pregnant women with the GI, which divided into 2 groups: primary – 30 pregnant women with the use of recommended prophylaxis complex (specific immunoglobulins, interferon a-2b, flavonoids, probiotics, arginine glutamate), the comparison group – 30 pregnant women with the knowledge of the pregnancy according to the Ministry of Health reports.

Results. The recommended treatment course of pregnancy complication rates decreased by 23.3%: almost 2-fold reduces the incidence of placental insufficiency, preeclampsia, and, respectively, and fetal distress – from 36.7 to 20.0%. The frequency of abnormal blood loss was 10.0 vs. 20.0%, fetal distress in labor – 16.7 against 30.0%. Significantly improving the condition of children at birth: in satisfactory condition (without asphyxia) was born 60.0 against 37.9% of children (p <0.05). Relatively better and during the period of early neonatal adaptation: 1.5–2 times lower than the frequency of jaundice, hemorrhagic syndrome, and gastrointestinal. Significantly reduces the incidence of life-threatening syndromes and further development of the child as neurological (up 23.3% vs. 44.8%, p <0.05) and RDS (up 16.7% vs. 37.9%, p<0.05).

Conclusions. Security and high efficiency of the proposed complex of perinatal fetal protection for HIV-infected pregnant women with herpes infection can be recommended for implementation in antenatal clinics and maternity homes.

Key words: pregnancy, fetus, newborn, HIV, herpes virus infection, therapy.


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