• Recurrent respiratory diseases in children: the physician’s action algorithm (lecture)

Recurrent respiratory diseases in children: the physician’s action algorithm (lecture)

SOVREMENNAYA PEDIATRIYA.2018.3(91):92-97; doi 10.15574/SP.2018.91.92

Chernyshova L. I.
Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

Respiratory infections in the world rank first among all diseases, 85% of these infections occur in children. Recurrent respiratory diseases (RRD) are the main cause of parents' anxiety, a visit to a doctor, a decrease in visits to a kindergarten and a school, and hospitalization. Immunodeficiency as a cause of RRD appears not more than in 10% of children. One of the leading causes of repeated respiratory symptoms is allergy, an appropriate specific therapy of which is worked out. In 1.5% of children with RRD, the serious, but not immune, violations are found; the majority of children are apparently healthy. It is considered that 6–10 episodes of ARVI per year for some children are necessary to form the immunity against different respiratory virus. The trigger factors of RRD include visiting organized preschool groups, passive smoking, and air pollution in the cities. According to the WHO, human health, general resistance to infections by 60% depends on lifestyle, including nutrition, motion activity, and emotional state. Colonizational resistance of mucous membranes is provided by microflora. At the early stages of life, the microbiota «educates» the immune system to fight with pathogens. Probiotics are used to support microflora. The article presents the results of meta-analyses, which prove the possibility of loss in frequency and duration of RRD when using probiotics. Emphasize is made on the strain3specific effect of probiotic bacteria. To prevent and/or treat respiratory infections, there was developed and patented a probiotic, which in Europe is registered under the brand name BIFIVIR, and in Ukraine as FLUVIR. The microorganisms of this multiprobiotic increase the Th1 response, which is known to provide antimicrobial and antiviral immunity, and in addition, not only do not stimulate the Th2 response, but also reduce it, that is, reduce allergisation.

Key words: recurrent respiratory infections, children, probiotics.

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