HEALTH OF WOMAN WH_№2_2013

  • Scientific and practical journal
  • ISSN 2307-5074 (Online); ISSN 1992-5921 (Print)

  • DOI:
  • DOI: 10.15574/HW
  • Circulation -
  • 5500
  • Format of the edition -
  • 280x210 mm
  • Frequency -
  • 10 issues a year

Vovk I. B., Chubey G. М., Kondratyuk V. K., Podolyaka D. V.

Ovarian tumor lesions: etiology, pathogenesis, diagnosis and treatment.

11

This article presents the etiopathogenic, classification, clinical, diagnostic and therapeutic approaches to the management of patients with tumor formation in the ovaries. The main directions of treatment depending on the age, reproductive intentions and gistotipa tumor formation, given the possibility of hormonal and nonhor-monal phytoselective correction in the treatment and prevention of benign ovarian tumors.

Key words: ovarian tumor lesions, phytoselective correction, treatment.

 

 

Перинатальные центры в Украине: новая идеология, новые перспективы.

20

 

 

Shishkova V. N.

The questions of modern contraception. The focus on the risk of thromboses and metabolic violations.

22

The individual approach is very important at the purpose of oral contraceptives. There are a lot of complica-tions at the wrong application. The author recommends local contraception.

Key words: thrombosis, metabolic violations, oral contraceptives, local contraception.

 

 

Громова О. А., Торшин И. Ю., Лиманова О. А., Никонов А. А.

Патофизиология вегетативно-сосудистых пароксизмов (приливы) у женщин в период менопаузы и механизм действия β-аланина. Новая клинико-фармакологическая концепция.

28

 

 

Kondratiuk V., Litvinenko R.

Urinary incontinence in women (etiology, diagnostic, treatment).

35

Article highlights the epidemiological features of urinary incontinence and determines the place of overactive bladder (OAB) in the structure of neurogenic voiding disorders. This article describes the classification of uri-nary incontinence, the main pathogenetic mechanisms and risk factors for this disease. The algorithm for examination of patients with neurogenic voiding disorders, including OAB, demonstrated in the article. The paper considers the main treatments for urinary incontinence and provides an assessment of conservative and surgical methods of treatment. Particular attention is given to the diagnostic criteria of OAB and pharmacological therapy opportunities of symptoms associated with this condition. The application algorithm of anti-muscarinic drugs in OAB based on comprehensive patients’ examination for differential selection of conser-vative treatment is described in the article.

Key words: urinary incontinence, overactivebladder, antimuscarinic drugs, pharmacological therapy.

 

 

Gerasimova T., Gopchuk E., Chayka O. I.

Deksketoprofen – analgesia in obstetrician and gynaecology.

41

This article provides information about the effectiveness of dexketoprofen (Deksalgin) during postoperative analgesia in obstetric practice.

Key words: surgery, ceserian section, anesthesia, Deksketoprofen, Deksalgin.

 

 

Holyanovskyy O. V., Turkenich N. V., Shemberko A. V.

Complex therapy of vaginitis in pregnant women at risk.

45

The methods for preventing infectious and inflammatory complications in pregnant women during labor and the postpartum period. The study included 60 pregnant women at high risk for infectious complications (col-pitis, vulvovaginitis). Found that when the initial high number of microorganisms in the vagina in women from the group on the background of the drug benzydamine hydrochloride (Tantum Rosa), their number decreas-ed by the third day. Patients of the main group was also changing the balance of the vaginal flora with an in-crease in the number of lactobacilli in comparison with the control group. The results showed the efficacy of benzydamine hydrochloride for prevention colpitis and vulvovaginitis in pregnant women at risk.

Key words: urogenital infections, benzydamine hydrochloride, colpitis.

 

 

Дубчак А. Е., Милевский А. В., Довгань Е. Н.

Неспецифические воспалительные заболевания органов малого таза у женщин.

51

Проблема воспалительных заболеваний органов малого таза (ВЗОМТ) продолжает оставаться акту-альной. Практически все микроорганизмы, присутствующие во влагалище (за исключением лакто- и бифидобактерий), могут принимать участие в воспалительном процессе. Неадекватное лечение ВЗОМТ приводит к хронизации процесса, формируя основу патологических состояний, нарушающих фертильную функцию женщины и в ряде случаев требующих хирургической коррекции, принимает участие в развитии таких патологических процессов, как миома матки, эндометриоз, гиперпластичес-кие процессы эндометрия, бесплодие различного генеза, неопластические заболевания шейки матки, а также функциональные расстройства, нарушающие физиологическое течение беременности. В работе показана эффективность лечения ВЗОМТ препаратами Макмирор и Макмирор Комплекс. В отли-чие от аналогичных препаратов Макмирор и Макмирор Комплекс не содержат антибиотиков и не вы-зывают дисбактериоза влагалища: по мере подавления патогенной флоры наблюдается рост лакто- и бифидумбактерий и восстановление нормоценоза влагалища и нормального уровня кислотности влагалищной среды

Ключевые слова: ВЗОМТ, лечение, Макмирор, Макмирор Комплекс.

 

 

Завадская Т. С.

Расстройства психосоматического здоровья, связанные с абортом: современное решение в акушерско-гинекологической практике.

56

Изучено психоэмоциональное состояние женщин в динамике до и после аборта в зависимости от способа искусственного прерывания беременности. Выявлена свіязь между соматическими жалобами и депрессивным расстройством. Оценено влияние соматизированной депрессии у женщин на выбор способа прерывания нежелательной беременности и их качество жизни.

Ключевые слова: нежелательная беременность, аборт, соматизированная депрессия, качество жизни.

 

 

Goncharenko D. O., Zhezher A. O.

Fluid replacement of obstetric hemorrhage: theory and practice.

62

The article provides a nomogram for quickly assess the severity of obstetric hemorrhage and calculate the approximate qualitative and quantitative composition of fluid replacement therapy.

Key words: obstetric hemorrhage, nomogram, fluid replacement therapy.

 

 

Makarenko M. V., Hovsieiev D. O., Bazeliuk O. M.

Argon plasma coagulation with repeated cesarean section.

65

This article provides information about the effectiveness of intraoperative hemostasis, prevention of septic complications and hemorrhagic nature in patients with recurrent cases laparotomy in anamnesis about ce-sarean section during treatment with argon plasma coagulation of tissue.

Key words: cesarean section, complications, prevention, argon plasma coagulation.

 

 

Shurpyak S. A.

Uterine fibroids and pregnancy: clinical features, complications and treatment.

67

Fibroid in pregnancy is common in clinical obstetric practice. The topic is becoming more relevant in conte-mporary obstetrics due to the demographic shift towards delayed childbearing, the rising rate of obesity, and many pregnancies occurring after the treatment of fibroids. However, there are conflicting reports in the lite-rature on many socalled fibroid complications in pregnancy, and there are inadequate data on the optimum management strategy. An evidence base is lacking on the pregnancy outcome of many conventional and newer treatment modalities of fibroids. This review addresses the characteristics and behaviour of fibroids during pregnancy, their incidence and demography, diagnosis, the complications that can arise during pregnancy and their antenatal management, the labour pattern, mode of delivery and the postpartum course, with critical appraisal of the literature together with certain special situations such as pregnancy after various ty-pes of myomectomy and uterine arterial embolisation.

Key words: fibroids, uterine leiomyoma, pregnancy complications, delivery, diagnosis, treatment.

 

 

Kossulnikova L. F., Syrovatko L. N., Bogoslovova G. E.

Use of Polygynax in the treatment of infectious vaginitis during the se-cond trimester of pregnancy.

74

Use of Polygynax in pregnant women is reasonable as the prescription of some antibacterial products is ban-ned by Ministry of Health orders. The efficacy of Polygynax is proved by clinical examination, nystatyn in its composition prevents from candida vulvovaginitis, negative effects on vaginal microbiocenosis are absent so the use of probiotics is unnecessary. Polygynax combines simplicity with usability and it can be recommended to pregnant women from the second trimester of pregnancy.

Key words: pregnancy, infectious vaginitis Polygynax, treatment.

 

 

Kozlov P. V.

The efficacy of tocolytic therapy in incomplete pregnancy and premature rupture of the membranes.

76

The article presents data of the study confirming that prolonged use of tocolytic medication significantly inc-reases the latent period in PROM at 25-30 wks of gestation, giving time necessary for corticosteroid exposu-re. Considering a favorable effect of tocolytic therapy on the fetoplacental system and possible reduction of the rate of loss of amniotic fluid, prolonged tocolytic therapy is indicated until 31 wk of gestation in the abse-nce of indications to preterm delivery. However, in PROM at 31-33 wks of gestation tocolysis is expedient only for the period of drug-based prophylaxis of RDS of the fetus.

Key words: premature rupture of membranes, tocolytic therapy, prevention of fetal respiratory distress syndrome, Ginipral.

 

 

Kornitskaia A. G., Danilenko E. G., Raksha I. I., Bil I. A., Dubenko O. D.

Pregravid training for women with the syndrome of pregnancy loss and thyroid disease.

79

The work presentsdata on the statusof thyroidglands of womenwith the syndromeof fetal loss.Developed and implemented asystempregravidpreparation, andshows the results ofthe effectiveness ofthe developed sys-tem.

Key words: thyroid syndrome, fetal loss, pregravid preparation.

 

 

Avramenko T. V., Shevchenko A. A., Lapko P. V.

Evaluation of the psycho-emotional state with the change of the vegeta-tive response in the neurological profile of the pregnants with congenital pathology of the central nervous system of the fetus.

83

In this paper we measured the psycho-emotional state with the assessment of the level of depression, Kerdo vegetative index, Hildebrandts coefficient and vegetative reflexes in pregnant women with congenital patho-logy of the central nervous system of the fetus. It has been shown disorders of intersystem relations in the functional system of pregnant women with the stress with severe vegetative dystonia: increase of the Kerdo vegetative index, Hildebrandts coefficient and abnormal directionality of the vegetative reflexes. There were grounded the necessity of the modern method of neuroimaging – magnetic resonance for the purposes of the optimization of prenatal diagnostics and evaluation of the structures of the growing brain.

Key words: congenital pathology, central nervous system, psycho-emotional state, pregnancy, fetus.

 

 

Veropotvelyan P. N., Guzhevskaya I. V., Veropotvelyan N. P., Tsekhmistrenko I. S., Pivnev M. S.

Pregnancy and delivery in patients with the metabolic syndrome on the obesity background.

90

With the aim of investigating various pathological factors a complex examination of 117 pregnant with the metabolic syndrome (MS) on the obesity background is performed. It is determined that pregnant with MS on the obesity background suffer gestosis, fetoplacental dysfunction – premature placenta maturing, abundance of water, fetal hypoxia, gestational diabetes (GD). The main role in the formation of MS is played by an exte-nsive body weight with the disturbance of the carbohydrate lipid exchange. For the metabolic disturbances prophylaxis it is necessary to take measures on order to reduce the body weight in patients of the reproductive age prior the pregnancy.

Key words: pregnancy, obesity, metabolic syndrome, treatment.

 

 

Боровкова Е. И.

Взаимодействие возбудителей инфекции с организмом беременной как фактор риска внутриутробного инфицирования плода.

95

 

 

Ruban J. A.

Comparative aspects of a clinical current of І trimester of pregnancy at women after auxiliary reproductive technologies.

100

Results of the spent researches testify, that early terms of pregnancy are «critical» for patients with barre-ness in the anamnesis, irrespective of its reason and are characterised by higher frequency of reproductive losses and interruption threats in comparison with ІІ and ІІІ trimesters of pregnancy. The risk of a failure raises at development of a syndrome of hyperstimulation of ovariums. The received results are necessary for considering by working out of algorithm of diagnostic and treatment-and-prophylactic actions.

Key words: auxiliary reproductive technologies, І trimester of pregnancy.

 

 

Romanenko N. M.

Modern aspects of patogenesise of aneamical syndrome at pregnant women.

103

Results of the spent researches about an essential role blood whey ferritine in patogenesise of aneamical syndrome at pregnant women. The established features patogenesise of aneamical syndrome are necessary for considering by working out of a complex of diagnostic and treatment-and-prophylactic actions.

Key words: aneamical syndrome, patogenesise, blood whey ferritine.

 

 

Rynzhuk V. Ye.

Ultrasonic examination of kidneys and doppler velocimetry of renal cir-culation in pregnant women with asymptomatic bacteriuria.

105

The authors investigated changes in the renal circulation typical for pregnant women with asymptomatic bacteriuria with certain disorders of the pro-inflammatory and anti-inflammatory immunity system. The said changes in circulation indicate the venous drainage impairment processes accompanied by increased vas-cular resistance; in case any germs are present and in case no adequate response from the immune system is available, the above changes can result in the development of gestational pyelonephritis

Key words: pregnancy, asymptomatic bacteriuria, ultrasonic examination of kidneys, Doppler velocimetry of renal circulation.

 

 

Vdovichenko Iu. P., Goncharuk N. P., Gurzhenko O. Iu.

Dynamics of Caesarean sections frequency at extragenital pathology as the indication for the surgical delivery.

108

In the work there were analysed data on Caesarean sections frequency, on the Caesarean sections structure in the interests of mother, dynamics of Caesarean sections frequency at extragenital pathology during the period 2001-2011 years at the Kyiv municipal maternity hospital №1. The increase of Caesarean sections frequency is marked. Also the positive tendency of increase of nonurgentoperative interventions frequency pays attention on itself. For the studied period it is noted the considerable reduction of Cesarean sections frequency at extragenital pathology in the presence of the expert conclusion.

Key words: caesarian section, extragenital pathology.

 

 

Bagrij D. O.

Optimisation of tactics of conducting patients with obstetrical wound infections.

112

The received results testify, that preventive maintenance and treatment wound infections in obstetrics is difficult enough process and demands an estimation of many endo – and eczogene factors. The technique offered by us promotes adequate clarification wound to a surface, and then allows to stimulate processes fagocytosise and regenerations. In aggregate it allows to lower frequency wound infections from 23,3 % to 6,7 %, and also to seize results treatment and to reduce to 4,2 days stay of women in a hospital. It gives us the basis to recommend the developed technique in practical public health services.

Key words: obstetrics, wound infection, preventive maintenance, treatment.

 

 

Zhuk S. I.

Pregravidar preparation of women with dyshormonal disorders of the reproductive system.

114

149 patients who are planning pregnancy and have a reproductive system disorder (dyshormonal disorders by the type of the primary dysmenorrhea and women who went through a surgical or a conservative treat-ment of the 1st abdominal pregnancy) had a complex examination. A correlation between changes in hor-mone levels of a female reproductive system and the nature of somatic status disorders was established. The correction scheme of existing changes with Cyclodynon drug was proposed.

Key words: dyshormonal disorders; primary dysmenorrhea; Cyclodynon.

 

 

Kornatsky A. G., Vovk I. B., Kochubey G. V.

Non-hormonal correction of ovarian dysfunction inflammatory genesis.

119

In the study of hormonal homeostasis in women with chronic inflammatory genitals' processes were found reduced levels of sex hormones, indicating ovarian hypofunction. The inclusion of a comprehensive anti-inflammatory therapy of herbal preparation Tribestan was effective in most patients.

Key words. Inflammation of the genitals, ovarian hypofunction, Tribestan.

 

 

Petrova G. A.

Experience of using systemic antifungal drugs in urogenital candidiasis in women.

122

In the article we present the results of Kusum Healthcare preparations application – Eszol and Futsis – as complex therapy of woman urogenital candidiasis. These preparations have good fungicide activity. Eszol contains 100 mg of itraconazole in a tablet, Futsis contains 150 mg of fluconazole i in a tablet. Therapeutic efficiency of preparations is confirmed by laboratory indexes normalization and eradication of urogenital can-didiasis clinical implication within examined group of women.

Key words: Eszol, Futsis, candidiasis, urogenital.

 

 

Bulavenko O. V., Furman O. V.

The role of vitamin D in development and course of polycystic ovary syndrome.

125

Vitamin D deficiency may exacerbate symptoms of PCOS. Low level associated with decrease of BMI, insu-lin resistance, increase level of free testosterone, luteal phase deficiency ( low progesterone and shot luteal phase of MC), ovulatory dysfunction and menstrual disorder.

Key words: polycystic ovary syndrome, vitamin D, calcidiol, calcitriol, insulin resistance, free testosterone, progesterone.

 

 

Gorovenko N. G., Podolsky S. V., Zakharenko N. F.

Molecular genetic risk markers for endometriosis.

128

Endometriosis is currently viewed as multifactorial disease, which can appear due to interaction of multiple genes, as well as the environment factors. In the article is reviewed informational value of several genetic markers, associated with risk of development of endometriosis. Frequency of GSTM1, GSTT1, CYP2D6*4 polymorphisms among the patients with endometriosis was examined. According to the results of the inve-stigation risk of development of the endometriosis was higher for carriers of genotype GSTM1”+”/ GSTT1”-”/CYP2D6wt/wt and GSTM1 “+”/GSTT1 “+”/CYP2D6*4/*4 [χ2 – 6,20; OR – 2,88 (1,30–6,41)] and [χ2 – 3,93, OR – 8,62 (1,03–72,04)] in comparison to control group. Presence of the genotype GSTM1”+“/GSTT1”+“/CYP2D6 wt/wt was associated with decreased risk of disease development.

Key words: endometriosis, molecular genetic markers, genes, environmental factors.

 

 

Vdovychenko Yu. P., Baranovskaya G. A.

Features system and local fagocytose at infectious-inflammatory diseases of a vagina.

132

Results of the spent researches testify about an essential role of system and local fagocytose at an estima-tion of a condition of local factors of protection at patients with infectious-inflammatory diseases of a vagina. The received results are necessary for considering by working out of algorithm of diagnostic and treatment-and-prophylactic actions.

Key words: infectious-inflammatory diseases of a vagina, system and local fagocytose.

 

 

Sadovoj A. P.

Ehografical diagnostics of anomalies of uterus and vagina.

136

Results of the spent researches testify, that ultrasonic ehografia has allowed to reveal congenital anomalies of development of a uterus and a vagina at 89,4 %, to establish their form at 51,8 % of girls-teenagers. It is most often established partial aplasia of vaginas at a functioning uterus and full aplasia of uterus and vagi-nas (82,1 %), uterus and vagina doubling (79,2 %), is more rare – one-horn uterus with an additional rudi-mentary horn (40,0 %). The big difficulties have arisen in differential diagnostics between intrauterine parti-tion and a two-horned uterus. The received results are necessary for considering by working out of algorithm of treatment-and-prophylactic actions.

Key words: anomalies of development of a uterus and a vagina, ehografical diagnostics.

 

 

Bodnarjuk O. I., Аndriiets’ O. A., Humenna K. Y.

Optimization of complex treatment salpingoophoritis on the background inflammatory diseases of kidneys and bladder in adolescent girls.

139

The paper presents and analyzes the results of an examination and treatment of 47 girls of pubertal age, suffering from salpingoophoritis with underlying inflammatory diseases of the kidneys and urinary bladder. The use of a combined phytopreparation – LeСranTM in a multimodality treatment of salpingooophoritis in girls with underlying inflammatory diseases of the kidneys and urinary bladder is pathogenetically substan-tiated that is confirmed by laboratory studies and the clinical picture.

Key words: teenage girls, salpingoophorites, LeСranTM.

 

 

Veropotvelyan N. P., Oshovskyy V. I., Bondarenko A. A., Gladkaya O. N., Usenko T. V., Pivnev M. C.

The rare case of maternal mirror syndrome due to non-immune fetal hydrops caused by an abnormality of umbilical vessels.

142

The case of a rare syndrome surveillance (Ballantyne syndrome) in 25-years-old pregnant, realized in mater-nal polyserositis accompanied by fetal hydrops and severe polyhydramnion was presented. Taking into acco-unt the fact that the cause of fetal hydrops could not be defined, hypothetically an anomalous quantity of the umbilical vessels could serve as one. This article attempts to parse clinically the complicated obstetric situa-tion.

Key words: maternal mirror syndrome, fetal hydrops, prenatal intervention.

 

 

Lyanna M. V.

The Analysis of Phoeto-placental Complex Status in Pregnants with Le-yomyoma and Cervical Pathology in Anamnesis.

149

In article the main peculiarities of pregnancy labour,phoetus and phoetoplacentae complex are analyced in women with leyomyoma and cervical pathology in anamnesis.

Key words: pregnancy, labour, phoetus, placenta, leyomyoma, cervical pathology.

 

 

Nevirkovets A. A.

Perinatal hypoxic damage to the central nervous system in newborns and dynamic changes of free heparin in the treatment of blood plasma.

151

Data are submitted on physiological role of heparin, on changes in its level in the blood plasma of 33 new-born babies with hypoxic affection of the central nervous system (CNS). It is shown that in neonates with hy-poxic affection of CNS the level of heparin in blood plasma gets singificantly increased. A possible role is dis-cussed of heparin in formation of the metabolic intoxication syndrome in hypoxic affection of CNS in newborn infants.

Key words: central nervous system, newborn infants, heparin, blood plasma.

 

 

Kaminsky V., Shipkо I.

Pregravidar preparations, pregnancy and childbirth in women with herpes virus and cytomegalovirus infection after assisted reproductive techniques.

153

The studies show that using the proposed algorithm preventive measures in women with herpes and cyto-megalovirus infection after use of assisted reproductive technology on the basis of clinical and ultrasound study, immunological, microbiological, virological features of placenta led to a reduction in the incidence of obstetric and perinatal these pregnant women.

Key words: cytomegalovirus infection, genital herpes, pregnancy, miscarriage, birth, fetus, newborn, assis-ted reproductive technologies, prevention of complications of gestational.

 

 

Vdovichenko J. P., Gopchuk E. N.

Gravagin (metronidazol) for intravaginal use – topical therapy of urogenital trichomoniasis.

156

The results of studies of the effectiveness and safety of topical metronidazol in the treatment of urogenital trichomoniasis in women of reproductive age are presented in the article.

Key words: urogenital trichomoniasis, metronidazol, suppository, Gravagin.

 

 

Podolsky V. V., Hominskaya Z. B., Voloshin A. V.

Particularly hormonal balance and sexual health in HIV-infected women with chronic inflammatory diseases of the genital organs.

161

This paper contains hormonal examination and anonymous survey of 120 HIV-infected women (basic group) of reproductive age with chronic inflammatory genitalia diseases. The control group included 30 healthy wo-men of reproductive age. The comparison group contained 240 AIDS-negative women. The necessity of ti-mely prevention and treatment of hormonal and sexual disorders as an integral part of effective measures for prevention of HIV transmission to women of reproductive age with chronic inflammatory genitalia diseases was proved.

Key words: hormonal state, sexual health, chronic inflammatory genitalia diseases, reproductive age, HIV-infected women.

 

 

Yaremchuk T. P.

Organs and systems state in the pregnant and fetus with syphilis.

166

Contemporary clinical peculiarity of syphilis in pregnancy have been defined on the ground of analysis of contemporary scientific research. Syphilis negative disturbs pregnancy course, changes of biochemical blo-od indicators, induces of hypercytokinemia and hypercoagulation. Syphilis antiphospholipid antibodies differs from antiphospholipid syndrome antibodies. They are β2-glicoproteinІ-independent antibodies and don't deve-lop trombophilia. It is showed the pregnants with syphilis are infected by other STI in 30>60%. Vaginal dys-biosis is present. Different forms of intestine dysbacteriosis also are present. Morphological characteristic of afterbirths in cases of syphilis are done. They characterized by villusitis with stroma fibrosis, vasculitis with perivascular fibrosis and vascular obliteration, pathological villi immaturity. Placental dysfunction are develo-ped. Maternal genesis of lymphocytes and neutrophil leucocytes infiltration in villi was confirmed by immuno-genetical methods. Contemporary data about intrauterine infection influence on fetus and conception of ante-natal fetus brain protection are presented. Placental dysfunction treatment necessity in cases of syphilis are grounded.

Key words: pregnancy, syphilis, afterbirth, placental dysfunction, fetus, congenital syphilis.

 

 

Lyovkina O. L.

Clinico-anamnestic, social and psychological peculiarities of reproducti-ve age women with primary stress-induced infertility.

174

Social conditions.clinico-anamnestic and psychological peculiarities of reproductive age women with primary stress-induced infertility were analyzed and was revealed presence of social characteristics, life mode har-mfulnesses, chronic and acute psychoemotional stresses, which may be as a trigger mechanism or main re-ason of stress-induced infertility.

Key words: stress, infertility, life mode harmfulnesses, anxiety.

 

 

Hafiichuk R. G.

Individual approach to ovaries diagnosis in women with exhausted ovary syndrome.

181

Ultrasound investigation and Doppler velocimetry of ovaries enabled a thorough approach to evaluation of the ovarian response and correction of ovarian stimulation. Women with exhausted ovary syndrome are characterized by insufficient increase in the total velocity of perifollicular circulation and high values of the resistance index, which is the evidence of insufficient vascularization of the dominating follicle in the pre-ovulatory period. The results achieved enable specification of the diagnosis and selection of an optimal as-sisted reproductive technologies scheme.

Key words: infertility, exhausted ovary syndrome, doppler velocimetry.

 

 

«Тест, пожалуйста, скажи, да всю правду доложи…».

184

 

 

Vovk I. B., Chubey G. М., Kondratyuk V. K., Podolyaka D. V.

Ovarian tumor lesions: etiology, pathogenesis, diagnosis and treatment.

11

This article presents the etiopathogenic, classification, clinical, diagnostic and therapeutic approaches to the management of patients with tumor formation in the ovaries. The main directions of treatment depending on the age, reproductive intentions and gistotipa tumor formation, given the possibility of hormonal and nonhor-monal phytoselective correction in the treatment and prevention of benign ovarian tumors.

Key words: ovarian tumor lesions, phytoselective correction, treatment.

 

 

Перинатальные центры в Украине: новая идеология, новые перспективы.

20

 

 

Shishkova V. N.

The questions of modern contraception. The focus on the risk of thromboses and metabolic violations.

22

The individual approach is very important at the purpose of oral contraceptives. There are a lot of complica-tions at the wrong application. The author recommends local contraception.

Key words: thrombosis, metabolic violations, oral contraceptives, local contraception.

 

 

Громова О. А., Торшин И. Ю., Лиманова О. А., Никонов А. А.

Патофизиология вегетативно-сосудистых пароксизмов (приливы) у женщин в период менопаузы и механизм действия β-аланина. Новая клинико-фармакологическая концепция.

28

 

 

Kondratiuk V., Litvinenko R.

Urinary incontinence in women (etiology, diagnostic, treatment).

35

Article highlights the epidemiological features of urinary incontinence and determines the place of overactive bladder (OAB) in the structure of neurogenic voiding disorders. This article describes the classification of uri-nary incontinence, the main pathogenetic mechanisms and risk factors for this disease. The algorithm for examination of patients with neurogenic voiding disorders, including OAB, demonstrated in the article. The paper considers the main treatments for urinary incontinence and provides an assessment of conservative and surgical methods of treatment. Particular attention is given to the diagnostic criteria of OAB and pharmacological therapy opportunities of symptoms associated with this condition. The application algorithm of anti-muscarinic drugs in OAB based on comprehensive patients’ examination for differential selection of conser-vative treatment is described in the article.

Key words: urinary incontinence, overactivebladder, antimuscarinic drugs, pharmacological therapy.

 

 

Gerasimova T., Gopchuk E., Chayka O. I.

Deksketoprofen – analgesia in obstetrician and gynaecology.

41

This article provides information about the effectiveness of dexketoprofen (Deksalgin) during postoperative analgesia in obstetric practice.

Key words: surgery, ceserian section, anesthesia, Deksketoprofen, Deksalgin.

 

 

Holyanovskyy O. V., Turkenich N. V., Shemberko A. V.

Complex therapy of vaginitis in pregnant women at risk.

45

The methods for preventing infectious and inflammatory complications in pregnant women during labor and the postpartum period. The study included 60 pregnant women at high risk for infectious complications (col-pitis, vulvovaginitis). Found that when the initial high number of microorganisms in the vagina in women from the group on the background of the drug benzydamine hydrochloride (Tantum Rosa), their number decreas-ed by the third day. Patients of the main group was also changing the balance of the vaginal flora with an in-crease in the number of lactobacilli in comparison with the control group. The results showed the efficacy of benzydamine hydrochloride for prevention colpitis and vulvovaginitis in pregnant women at risk.

Key words: urogenital infections, benzydamine hydrochloride, colpitis.

 

 

Дубчак А. Е., Милевский А. В., Довгань Е. Н.

Неспецифические воспалительные заболевания органов малого таза у женщин.

51

Проблема воспалительных заболеваний органов малого таза (ВЗОМТ) продолжает оставаться акту-альной. Практически все микроорганизмы, присутствующие во влагалище (за исключением лакто- и бифидобактерий), могут принимать участие в воспалительном процессе. Неадекватное лечение ВЗОМТ приводит к хронизации процесса, формируя основу патологических состояний, нарушающих фертильную функцию женщины и в ряде случаев требующих хирургической коррекции, принимает участие в развитии таких патологических процессов, как миома матки, эндометриоз, гиперпластичес-кие процессы эндометрия, бесплодие различного генеза, неопластические заболевания шейки матки, а также функциональные расстройства, нарушающие физиологическое течение беременности. В работе показана эффективность лечения ВЗОМТ препаратами Макмирор и Макмирор Комплекс. В отли-чие от аналогичных препаратов Макмирор и Макмирор Комплекс не содержат антибиотиков и не вы-зывают дисбактериоза влагалища: по мере подавления патогенной флоры наблюдается рост лакто- и бифидумбактерий и восстановление нормоценоза влагалища и нормального уровня кислотности влагалищной среды

Ключевые слова: ВЗОМТ, лечение, Макмирор, Макмирор Комплекс.

 

 

Завадская Т. С.

Расстройства психосоматического здоровья, связанные с абортом: современное решение в акушерско-гинекологической практике.

56

Изучено психоэмоциональное состояние женщин в динамике до и после аборта в зависимости от способа искусственного прерывания беременности. Выявлена свіязь между соматическими жалобами и депрессивным расстройством. Оценено влияние соматизированной депрессии у женщин на выбор способа прерывания нежелательной беременности и их качество жизни.

Ключевые слова: нежелательная беременность, аборт, соматизированная депрессия, качество жизни.

 

 

Goncharenko D. O., Zhezher A. O.

Fluid replacement of obstetric hemorrhage: theory and practice.

62

The article provides a nomogram for quickly assess the severity of obstetric hemorrhage and calculate the approximate qualitative and quantitative composition of fluid replacement therapy.

Key words: obstetric hemorrhage, nomogram, fluid replacement therapy.

 

 

Makarenko M. V., Hovsieiev D. O., Bazeliuk O. M.

Argon plasma coagulation with repeated cesarean section.

65

This article provides information about the effectiveness of intraoperative hemostasis, prevention of septic complications and hemorrhagic nature in patients with recurrent cases laparotomy in anamnesis about ce-sarean section during treatment with argon plasma coagulation of tissue.

Key words: cesarean section, complications, prevention, argon plasma coagulation.

 

 

Shurpyak S. A.

Uterine fibroids and pregnancy: clinical features, complications and treatment.

67

Fibroid in pregnancy is common in clinical obstetric practice. The topic is becoming more relevant in conte-mporary obstetrics due to the demographic shift towards delayed childbearing, the rising rate of obesity, and many pregnancies occurring after the treatment of fibroids. However, there are conflicting reports in the lite-rature on many socalled fibroid complications in pregnancy, and there are inadequate data on the optimum management strategy. An evidence base is lacking on the pregnancy outcome of many conventional and newer treatment modalities of fibroids. This review addresses the characteristics and behaviour of fibroids during pregnancy, their incidence and demography, diagnosis, the complications that can arise during pregnancy and their antenatal management, the labour pattern, mode of delivery and the postpartum course, with critical appraisal of the literature together with certain special situations such as pregnancy after various ty-pes of myomectomy and uterine arterial embolisation.

Key words: fibroids, uterine leiomyoma, pregnancy complications, delivery, diagnosis, treatment.

 

 

Kossulnikova L. F., Syrovatko L. N., Bogoslovova G. E.

Use of Polygynax in the treatment of infectious vaginitis during the se-cond trimester of pregnancy.

74

Use of Polygynax in pregnant women is reasonable as the prescription of some antibacterial products is ban-ned by Ministry of Health orders. The efficacy of Polygynax is proved by clinical examination, nystatyn in its composition prevents from candida vulvovaginitis, negative effects on vaginal microbiocenosis are absent so the use of probiotics is unnecessary. Polygynax combines simplicity with usability and it can be recommended to pregnant women from the second trimester of pregnancy.

Key words: pregnancy, infectious vaginitis Polygynax, treatment.

 

 

Kozlov P. V.

The efficacy of tocolytic therapy in incomplete pregnancy and premature rupture of the membranes.

76

The article presents data of the study confirming that prolonged use of tocolytic medication significantly inc-reases the latent period in PROM at 25-30 wks of gestation, giving time necessary for corticosteroid exposu-re. Considering a favorable effect of tocolytic therapy on the fetoplacental system and possible reduction of the rate of loss of amniotic fluid, prolonged tocolytic therapy is indicated until 31 wk of gestation in the abse-nce of indications to preterm delivery. However, in PROM at 31-33 wks of gestation tocolysis is expedient only for the period of drug-based prophylaxis of RDS of the fetus.

Key words: premature rupture of membranes, tocolytic therapy, prevention of fetal respiratory distress syndrome, Ginipral.

 

 

Kornitskaia A. G., Danilenko E. G., Raksha I. I., Bil I. A., Dubenko O. D.

Pregravid training for women with the syndrome of pregnancy loss and thyroid disease.

79

The work presentsdata on the statusof thyroidglands of womenwith the syndromeof fetal loss.Developed and implemented asystempregravidpreparation, andshows the results ofthe effectiveness ofthe developed sys-tem.

Key words: thyroid syndrome, fetal loss, pregravid preparation.

 

 

Avramenko T. V., Shevchenko A. A., Lapko P. V.

Evaluation of the psycho-emotional state with the change of the vegeta-tive response in the neurological profile of the pregnants with congenital pathology of the central nervous system of the fetus.

83

In this paper we measured the psycho-emotional state with the assessment of the level of depression, Kerdo vegetative index, Hildebrandts coefficient and vegetative reflexes in pregnant women with congenital patho-logy of the central nervous system of the fetus. It has been shown disorders of intersystem relations in the functional system of pregnant women with the stress with severe vegetative dystonia: increase of the Kerdo vegetative index, Hildebrandts coefficient and abnormal directionality of the vegetative reflexes. There were grounded the necessity of the modern method of neuroimaging – magnetic resonance for the purposes of the optimization of prenatal diagnostics and evaluation of the structures of the growing brain.

Key words: congenital pathology, central nervous system, psycho-emotional state, pregnancy, fetus.

 

 

Veropotvelyan P. N., Guzhevskaya I. V., Veropotvelyan N. P., Tsekhmistrenko I. S., Pivnev M. S.

Pregnancy and delivery in patients with the metabolic syndrome on the obesity background.

90

With the aim of investigating various pathological factors a complex examination of 117 pregnant with the metabolic syndrome (MS) on the obesity background is performed. It is determined that pregnant with MS on the obesity background suffer gestosis, fetoplacental dysfunction – premature placenta maturing, abundance of water, fetal hypoxia, gestational diabetes (GD). The main role in the formation of MS is played by an exte-nsive body weight with the disturbance of the carbohydrate lipid exchange. For the metabolic disturbances prophylaxis it is necessary to take measures on order to reduce the body weight in patients of the reproductive age prior the pregnancy.

Key words: pregnancy, obesity, metabolic syndrome, treatment.

 

 

Боровкова Е. И.

Взаимодействие возбудителей инфекции с организмом беременной как фактор риска внутриутробного инфицирования плода.

95

 

 

Ruban J. A.

Comparative aspects of a clinical current of І trimester of pregnancy at women after auxiliary reproductive technologies.

100

Results of the spent researches testify, that early terms of pregnancy are «critical» for patients with barre-ness in the anamnesis, irrespective of its reason and are characterised by higher frequency of reproductive losses and interruption threats in comparison with ІІ and ІІІ trimesters of pregnancy. The risk of a failure raises at development of a syndrome of hyperstimulation of ovariums. The received results are necessary for considering by working out of algorithm of diagnostic and treatment-and-prophylactic actions.

Key words: auxiliary reproductive technologies, І trimester of pregnancy.

 

 

Romanenko N. M.

Modern aspects of patogenesise of aneamical syndrome at pregnant women.

103

Results of the spent researches about an essential role blood whey ferritine in patogenesise of aneamical syndrome at pregnant women. The established features patogenesise of aneamical syndrome are necessary for considering by working out of a complex of diagnostic and treatment-and-prophylactic actions.

Key words: aneamical syndrome, patogenesise, blood whey ferritine.

 

 

Rynzhuk V. Ye.

Ultrasonic examination of kidneys and doppler velocimetry of renal cir-culation in pregnant women with asymptomatic bacteriuria.

105

The authors investigated changes in the renal circulation typical for pregnant women with asymptomatic bacteriuria with certain disorders of the pro-inflammatory and anti-inflammatory immunity system. The said changes in circulation indicate the venous drainage impairment processes accompanied by increased vas-cular resistance; in case any germs are present and in case no adequate response from the immune system is available, the above changes can result in the development of gestational pyelonephritis

Key words: pregnancy, asymptomatic bacteriuria, ultrasonic examination of kidneys, Doppler velocimetry of renal circulation.

 

 

Vdovichenko Iu. P., Goncharuk N. P., Gurzhenko O. Iu.

Dynamics of Caesarean sections frequency at extragenital pathology as the indication for the surgical delivery.

108

In the work there were analysed data on Caesarean sections frequency, on the Caesarean sections structure in the interests of mother, dynamics of Caesarean sections frequency at extragenital pathology during the period 2001-2011 years at the Kyiv municipal maternity hospital №1. The increase of Caesarean sections frequency is marked. Also the positive tendency of increase of nonurgentoperative interventions frequency pays attention on itself. For the studied period it is noted the considerable reduction of Cesarean sections frequency at extragenital pathology in the presence of the expert conclusion.

Key words: caesarian section, extragenital pathology.

 

 

Bagrij D. O.

Optimisation of tactics of conducting patients with obstetrical wound infections.

112

The received results testify, that preventive maintenance and treatment wound infections in obstetrics is difficult enough process and demands an estimation of many endo – and eczogene factors. The technique offered by us promotes adequate clarification wound to a surface, and then allows to stimulate processes fagocytosise and regenerations. In aggregate it allows to lower frequency wound infections from 23,3 % to 6,7 %, and also to seize results treatment and to reduce to 4,2 days stay of women in a hospital. It gives us the basis to recommend the developed technique in practical public health services.

Key words: obstetrics, wound infection, preventive maintenance, treatment.

 

 

Zhuk S. I.

Pregravidar preparation of women with dyshormonal disorders of the reproductive system.

114

149 patients who are planning pregnancy and have a reproductive system disorder (dyshormonal disorders by the type of the primary dysmenorrhea and women who went through a surgical or a conservative treat-ment of the 1st abdominal pregnancy) had a complex examination. A correlation between changes in hor-mone levels of a female reproductive system and the nature of somatic status disorders was established. The correction scheme of existing changes with Cyclodynon drug was proposed.

Key words: dyshormonal disorders; primary dysmenorrhea; Cyclodynon.

 

 

Kornatsky A. G., Vovk I. B., Kochubey G. V.

Non-hormonal correction of ovarian dysfunction inflammatory genesis.

119

In the study of hormonal homeostasis in women with chronic inflammatory genitals' processes were found reduced levels of sex hormones, indicating ovarian hypofunction. The inclusion of a comprehensive anti-inflammatory therapy of herbal preparation Tribestan was effective in most patients.

Key words. Inflammation of the genitals, ovarian hypofunction, Tribestan.

 

 

Petrova G. A.

Experience of using systemic antifungal drugs in urogenital candidiasis in women.

122

In the article we present the results of Kusum Healthcare preparations application – Eszol and Futsis – as complex therapy of woman urogenital candidiasis. These preparations have good fungicide activity. Eszol contains 100 mg of itraconazole in a tablet, Futsis contains 150 mg of fluconazole i in a tablet. Therapeutic efficiency of preparations is confirmed by laboratory indexes normalization and eradication of urogenital can-didiasis clinical implication within examined group of women.

Key words: Eszol, Futsis, candidiasis, urogenital.

 

 

Bulavenko O. V., Furman O. V.

The role of vitamin D in development and course of polycystic ovary syndrome.

125

Vitamin D deficiency may exacerbate symptoms of PCOS. Low level associated with decrease of BMI, insu-lin resistance, increase level of free testosterone, luteal phase deficiency ( low progesterone and shot luteal phase of MC), ovulatory dysfunction and menstrual disorder.

Key words: polycystic ovary syndrome, vitamin D, calcidiol, calcitriol, insulin resistance, free testosterone, progesterone.

 

 

Gorovenko N. G., Podolsky S. V., Zakharenko N. F.

Molecular genetic risk markers for endometriosis.

128

Endometriosis is currently viewed as multifactorial disease, which can appear due to interaction of multiple genes, as well as the environment factors. In the article is reviewed informational value of several genetic markers, associated with risk of development of endometriosis. Frequency of GSTM1, GSTT1, CYP2D6*4 polymorphisms among the patients with endometriosis was examined. According to the results of the inve-stigation risk of development of the endometriosis was higher for carriers of genotype GSTM1”+”/ GSTT1”-”/CYP2D6wt/wt and GSTM1 “+”/GSTT1 “+”/CYP2D6*4/*4 [χ2 – 6,20; OR – 2,88 (1,30–6,41)] and [χ2 – 3,93, OR – 8,62 (1,03–72,04)] in comparison to control group. Presence of the genotype GSTM1”+“/GSTT1”+“/CYP2D6 wt/wt was associated with decreased risk of disease development.

Key words: endometriosis, molecular genetic markers, genes, environmental factors.

 

 

Vdovychenko Yu. P., Baranovskaya G. A.

Features system and local fagocytose at infectious-inflammatory diseases of a vagina.

132

Results of the spent researches testify about an essential role of system and local fagocytose at an estima-tion of a condition of local factors of protection at patients with infectious-inflammatory diseases of a vagina. The received results are necessary for considering by working out of algorithm of diagnostic and treatment-and-prophylactic actions.

Key words: infectious-inflammatory diseases of a vagina, system and local fagocytose.

 

 

Sadovoj A. P.

Ehografical diagnostics of anomalies of uterus and vagina.

136

Results of the spent researches testify, that ultrasonic ehografia has allowed to reveal congenital anomalies of development of a uterus and a vagina at 89,4 %, to establish their form at 51,8 % of girls-teenagers. It is most often established partial aplasia of vaginas at a functioning uterus and full aplasia of uterus and vagi-nas (82,1 %), uterus and vagina doubling (79,2 %), is more rare – one-horn uterus with an additional rudi-mentary horn (40,0 %). The big difficulties have arisen in differential diagnostics between intrauterine parti-tion and a two-horned uterus. The received results are necessary for considering by working out of algorithm of treatment-and-prophylactic actions.

Key words: anomalies of development of a uterus and a vagina, ehografical diagnostics.

 

 

Bodnarjuk O. I., Аndriiets’ O. A., Humenna K. Y.

Optimization of complex treatment salpingoophoritis on the background inflammatory diseases of kidneys and bladder in adolescent girls.

139

The paper presents and analyzes the results of an examination and treatment of 47 girls of pubertal age, suffering from salpingoophoritis with underlying inflammatory diseases of the kidneys and urinary bladder. The use of a combined phytopreparation – LeСranTM in a multimodality treatment of salpingooophoritis in girls with underlying inflammatory diseases of the kidneys and urinary bladder is pathogenetically substan-tiated that is confirmed by laboratory studies and the clinical picture.

Key words: teenage girls, salpingoophorites, LeСranTM.

 

 

Veropotvelyan N. P., Oshovskyy V. I., Bondarenko A. A., Gladkaya O. N., Usenko T. V., Pivnev M. C.

The rare case of maternal mirror syndrome due to non-immune fetal hydrops caused by an abnormality of umbilical vessels.

142

The case of a rare syndrome surveillance (Ballantyne syndrome) in 25-years-old pregnant, realized in mater-nal polyserositis accompanied by fetal hydrops and severe polyhydramnion was presented. Taking into acco-unt the fact that the cause of fetal hydrops could not be defined, hypothetically an anomalous quantity of the umbilical vessels could serve as one. This article attempts to parse clinically the complicated obstetric situa-tion.

Key words: maternal mirror syndrome, fetal hydrops, prenatal intervention.

 

 

Lyanna M. V.

The Analysis of Phoeto-placental Complex Status in Pregnants with Le-yomyoma and Cervical Pathology in Anamnesis.

149

In article the main peculiarities of pregnancy labour,phoetus and phoetoplacentae complex are analyced in women with leyomyoma and cervical pathology in anamnesis.

Key words: pregnancy, labour, phoetus, placenta, leyomyoma, cervical pathology.

 

 

Nevirkovets A. A.

Perinatal hypoxic damage to the central nervous system in newborns and dynamic changes of free heparin in the treatment of blood plasma.

151

Data are submitted on physiological role of heparin, on changes in its level in the blood plasma of 33 new-born babies with hypoxic affection of the central nervous system (CNS). It is shown that in neonates with hy-poxic affection of CNS the level of heparin in blood plasma gets singificantly increased. A possible role is dis-cussed of heparin in formation of the metabolic intoxication syndrome in hypoxic affection of CNS in newborn infants.

Key words: central nervous system, newborn infants, heparin, blood plasma.

 

 

Kaminsky V., Shipkо I.

Pregravidar preparations, pregnancy and childbirth in women with herpes virus and cytomegalovirus infection after assisted reproductive techniques.

153

The studies show that using the proposed algorithm preventive measures in women with herpes and cyto-megalovirus infection after use of assisted reproductive technology on the basis of clinical and ultrasound study, immunological, microbiological, virological features of placenta led to a reduction in the incidence of obstetric and perinatal these pregnant women.

Key words: cytomegalovirus infection, genital herpes, pregnancy, miscarriage, birth, fetus, newborn, assis-ted reproductive technologies, prevention of complications of gestational.

 

 

Vdovichenko J. P., Gopchuk E. N.

Gravagin (metronidazol) for intravaginal use – topical therapy of urogenital trichomoniasis.

156

The results of studies of the effectiveness and safety of topical metronidazol in the treatment of urogenital trichomoniasis in women of reproductive age are presented in the article.

Key words: urogenital trichomoniasis, metronidazol, suppository, Gravagin.

 

 

Podolsky V. V., Hominskaya Z. B., Voloshin A. V.

Particularly hormonal balance and sexual health in HIV-infected women with chronic inflammatory diseases of the genital organs.

161

This paper contains hormonal examination and anonymous survey of 120 HIV-infected women (basic group) of reproductive age with chronic inflammatory genitalia diseases. The control group included 30 healthy wo-men of reproductive age. The comparison group contained 240 AIDS-negative women. The necessity of ti-mely prevention and treatment of hormonal and sexual disorders as an integral part of effective measures for prevention of HIV transmission to women of reproductive age with chronic inflammatory genitalia diseases was proved.

Key words: hormonal state, sexual health, chronic inflammatory genitalia diseases, reproductive age, HIV-infected women.

 

 

Yaremchuk T. P.

Organs and systems state in the pregnant and fetus with syphilis.

166

Contemporary clinical peculiarity of syphilis in pregnancy have been defined on the ground of analysis of contemporary scientific research. Syphilis negative disturbs pregnancy course, changes of biochemical blo-od indicators, induces of hypercytokinemia and hypercoagulation. Syphilis antiphospholipid antibodies differs from antiphospholipid syndrome antibodies. They are β2-glicoproteinІ-independent antibodies and don't deve-lop trombophilia. It is showed the pregnants with syphilis are infected by other STI in 30>60%. Vaginal dys-biosis is present. Different forms of intestine dysbacteriosis also are present. Morphological characteristic of afterbirths in cases of syphilis are done. They characterized by villusitis with stroma fibrosis, vasculitis with perivascular fibrosis and vascular obliteration, pathological villi immaturity. Placental dysfunction are develo-ped. Maternal genesis of lymphocytes and neutrophil leucocytes infiltration in villi was confirmed by immuno-genetical methods. Contemporary data about intrauterine infection influence on fetus and conception of ante-natal fetus brain protection are presented. Placental dysfunction treatment necessity in cases of syphilis are grounded.

Key words: pregnancy, syphilis, afterbirth, placental dysfunction, fetus, congenital syphilis.

 

 

Lyovkina O. L.

Clinico-anamnestic, social and psychological peculiarities of reproducti-ve age women with primary stress-induced infertility.

174

Social conditions.clinico-anamnestic and psychological peculiarities of reproductive age women with primary stress-induced infertility were analyzed and was revealed presence of social characteristics, life mode har-mfulnesses, chronic and acute psychoemotional stresses, which may be as a trigger mechanism or main re-ason of stress-induced infertility.

Key words: stress, infertility, life mode harmfulnesses, anxiety.

 

 

Hafiichuk R. G.

Individual approach to ovaries diagnosis in women with exhausted ovary syndrome.

181

Ultrasound investigation and Doppler velocimetry of ovaries enabled a thorough approach to evaluation of the ovarian response and correction of ovarian stimulation. Women with exhausted ovary syndrome are characterized by insufficient increase in the total velocity of perifollicular circulation and high values of the resistance index, which is the evidence of insufficient vascularization of the dominating follicle in the pre-ovulatory period. The results achieved enable specification of the diagnosis and selection of an optimal as-sisted reproductive technologies scheme.

Key words: infertility, exhausted ovary syndrome, doppler velocimetry.

 

 

«Тест, пожалуйста, скажи, да всю правду доложи…».

184