HEALTH OF WOMAN WH_№2_2012

  • Scientific and practical journal
  • ISSN 2307-5074 (Online); ISSN 1992-5921 (Print)

  • DOI:
  • DOI: 10.15574/HW
  • Circulation -
  • 5500
  • Format of the edition -
  • 280x210 mm
  • Frequency -
  • 10 issues a year

Корнацкая А. Г., Дубенко О. Д.

Доброкачественные заболевания молочних желез в практике аку-шера-гинеколога.

9

 

 

Медведь В. І.

Хронічна серцева недостатність у вагітних (клінічна лекція).

21

 

 

InterMedicalEcoCity на «MIPIM» – найбільшому авторитетному і пред-ставницькому інвестиційному форумі Європи.

28

 

 

Абрамов А. А.

Генетические анализы в медицине – современные возможности и перспективы.

30

 

 

Gerasimova T., Gopchuk E.

Chronic venous insufficiency – general medical problem or illness of civilization.

32

Chronic venous insufficiency (CVI) meets in 40–50% cases among an able to work population. One of etio-logic there is sexual belonging to the factors of development of CVI – women are ill in 1,5–2 times more often than men, what is assisted by pregnancy, hormonal changes in different age-related periods. over of ethiopa-thogenesis, clinic, diagnostic and treatment of this state, are brought with the use of preparations of first line of local therapy and prevention are featured in the article.

Key words: сhronic venous insufficiency, varicose illness of veins of lower limbs, treatment, prophylaxis, heparin, Lioton-1000.

 

 

Сантамария Ампаро

Предотвращение венозной тромбоэмболии во время беременности.

37

 

 

Vadillo-Ortega Felipe, Perichart-Perera Otilia, Espino Salvador, Avila-Vergara Marco Antonio, Ibarra Isabel, Ahued Roberto, Godines Myrna, Parry Samuel, Macones George,

Strauss Jerome F.

Лечебное действие L-аргинина и антиоксидантных витаминов при лечении преэклампсии у женщин группы повышенного риска: ран-домизированное контролируемое исследование.

41

 

 

Пирогова В. И.

Эстрадиола валерат и диеногест: нове возможности предупреждения непланируемой беременности и терапии тяжелых менструальных кровотечений (обзор клинических исследований).

49

В статье представлен обзор результатов клинических исследований препарата эстрадиола валерата и диеногеста (Э2В/ДНГ) – первого КОК с эстрадиола валератом в виде эстрогенового компонента, который по биоактивности идентичен эндогенному 17β-эстрадиолу. Клинические исследования показа-ли эффективность Э2В/ДНГ для предотвращения беременности (индекс Перла = 1,27), подтвердили благоприятный профиль кровотечения, с меньшим количеством общего числа дней кровотечения и с более короткими плановыми месячными, показали, что Э2В/ДНГ является эффективным в лечении тяжелых менструальных кровотечений. Препарат эстрадиола валерата и диеногеста напрямую сравнивался с несколькими другими существующими в настоящее время КОК, при этом были подтверждены его безопасность и хорошая переносимость. Частота неблагоприятных реакций при приеме Э2В/ДНГ сопоставима с эффектами других КОК; наиболее распространенными из которых являются головная боль и мастодиния.

Ключевые слова: контрацепция, диеногест, эстрадиола валерат, меноррагия.

 

 

Yavorskyi P. V.

Features of leiomyoma of uterus on background of obesity and connec-ted with metabolic syndrome.

58

Study of features of obesity influence on development of leiomyoma of uterus and both basic symptom at a metabolic syndrome is of interest not only from the point of view of exposure of possible general nosotropic not studied te end contradictory moments but also in the plan of exposure of objective criteria of cоmorbidity complication and oncologic risk.

Key words: leiomyoma of uterus, metabolic syndrome, obesity.

 

 

Suprunova T. V.

The problem of human papillomavirus infections in gynecology (literature review).

64

The article presents data about the etiology and pathogenesis, clinical manifestations of HPV infection vari-eties, modern approaches to diagnosis and treatment in the practice of an obstetrician-gynecologist. Special attention is given to the review of antiviral and immunomodulating drugs, an integrated method of treatment of genital human papillomavirus infection, based on the methods immunotropic and antiviral therapy in conju-nction with the local destruction of tumors.

Key words: HPV infection, clinical manifestations, diagnosis, current approaches to treatment, antiviral and immunomodulating drugs.

 

 

 

Жежер А. А., Гончаренко Д. А.

Коррекция метаболизма у женщин, перенесших операцию кесарева сечения.

77

 

 

Галушко О. А., Петриченко В. В.

Застосування внутрішньовенної форми парацетамолу в акушерській та гінекологічній практиці: сучасні можливості.

79

 

 

Safonova I. N., Lukianova I. S., Abdullaiev R. Y.

Sonography with Feto-fetale Transfusion Syndrom: differential diagnostics and differential therapeutic approaches (literature and case history review).

82

The article contents the literature data analytic review of the fetofetal transfusion version sand selective fetal growth restriction pathogenesis, clinical feature, antenatal ultrasound diagnostics and management. Daily ultrasound and Doppler research result in 10 pregnant women with monochorionic complicated twin preg-nancy, differential ultrasound and Doppler diagnostic signs, comparative analyses of perinatal outcomes are offered.

Key words: monochorionic twin pregnancy, fetofetal transfusion syndrome, selective fetal growth restriction, sonography, Doppler.

 

 

Tovstanovskaia V. A., Vorobei-Vikhovskaia V. N., Kruk O. Y.

Importance of modern diagnostics methods of the papillomavirus infec-tion during preclinical and early clinical stage.

88

In the title are observed the questions of a social important of HPV infection. The title deals with the main biological mechanisms of virus existent in a human’s organism. The possibility of today’s laboratory diagnostic and the diagnostic price of the exploration methods are discussed.

Key words: Human papilloma virus, papilloma virus infection, cancerogenesis.

 

 

Zhuk S. I., Grigorenko A. N.

Etiopathogenic approach to conservative treatment of varicose pelvic veins in women.

93

The aim of the work was clinical, laboratory and instrumental evaluation of the effectiveness of the proposed pathogenetically grounded, conservative treatment of varicose veins of the pelvis in women of reproductive age. Proposed, complex treatment included oral diosmin, hondroitynsulfat for 6 months and physiotherapy. The results of this study indicate, that the proposed treatment is quite effective, namely restoration of endo-thelial function provides varices, dynamic equilibrium between vasodilatation and vasoconstriction factors, normalization of rheological properties of blood and metabolism of connective tissue.

Key words: varicose veins of the pelvis, conservative treatment, flebotropytherapy.

 

 

Dankovich N. O., Zhuk S. I., Abliaieva E. Sh., Vorobei-Vykhovskaia V. M.

Placental dysfunction and naturopathic methods of treatment.

96

The title deals with the main aspects of pathogenesis of the placental insufficiency. The important of the pa-thogenetical therapy is discussed. The possibility of antigomotoxical therapy in the treatment of this disease are explained. The effectiveness of the including of Placenta compositum (Biologische Heilmittel Heel GmbH) to the course of complex therapy of placental insufficiency is studied.

Key words: placental insufficiency, antigomotoxical therapy, Placenta compositum.

 

 

Венцковский Б. М., Венцковский К. О.

Профилактика преэклампсии в условиях женских консультаций.

100

 

 

Савенкова О. Д.

Отчет по применению препарата Циклодинон.

102

 

 

Mazorchuk B. F., Konkov D. G., Chaika G. V.

Current approaches for treatment of early gestosis.

104

It is discovered that Hepasol(R) NEO 8% has brought to positive clinical and laboratory changes (decrease of nausea and vomiting, decrease of acetonuria, increase of total protein and K+, Na+ and Cl-, decrease of IL-2, TNF-α and increase of IL-10) of pregnant ladies of early gestosis.

Key words: hyperemesis gravidarum, Hepasol(R) NEO 8%, cytokines.

 

 

Кондратюк В. К., Коблош Н. Д., Горбань Н. Е., Архипова Н. А., Григорович Л. В., Емец Н. А.

Патогенетическое обоснование системного похода к лечению вос-палительных заболеваний женских половых органов.

107

В статье представлены данные литературы по проблеме лечения воспалительных заболеваний жен-ских половых органов. Для обеспечения эффективной терапии хронических воспалительных заболе-ваний органов малого таза у женщин следует применять системный подход, который включает етап-ность лечения, назначение антибактериальной терапии с учетом высеянной микрофлоры и ее чув-ствительности к антибиотикам, десенсибилизирующее, противокандидозное и симптоматическое лечение.

Ключевые слова: воспалительные заболевания женских половых органов, лечение, системный подход.

 

 

Бобрицкая В. В.

Динамика органических изменений молочной железы в процессе патогенетической терапии фиброзно-кистозной мастопатии.

113

 

 

Дубинина В. Г., Рыбин А. И.

Комбинированное органосохраняющее лечение начальных форм рака шейки матки у пациенток репродуктивного возраста.

119

 

 

Djobava E. M., Stepanian A. V., Panayotidi D. A., Bolkunova N. V., Dobrokhotova Yu. E.

The course features, diagnosis and treatment of placental insufficiency in varicosity.

121

Placental insufficiency (PI) is a major problem of modern perinatology. Chronic placental insufficiency (CPI) is observed in every third pregnant woman at high risk of perinatal pathology. Perinatal mortality reaches 60% in this group. We investigated the modern approaches to diagnosis, prevention and therapy of placental insufficiency, including during varicosity. We studied the efficacy of Phlebodia 600 in the combined therapy of patients with PI. Based on these findings we are recommend prevention of PI (by Phlebodia 600) for all preg-nant women with varicose veins, on the basis of morphologically confirmed reduction of placentas compen-satory reactions.

Key words: placental insufficiency, varicosity, Phlebodia 600.

 

 

Романенко Т. Г.

Комплексная профилактика гестозов у женщин в период преконцеп-ционной подготовки и во время беременности.

126

Результаты проведенных исследований свидетельствуют, что применение комплекса витаминов и минералов (Эмфетал) в преконцепционной подготовке и во время беременности, у женщин группы высокого риска по развитию гестоза, позволяет уменьшить вероятность перинатального риска, вос-полняет повышенную потребность беременной женщины в витаминах и минералах; уменьшает риск возникновения ранних гестозов, угрозы прерывания, частоты и тяжести преэклампсии, нормализует функциональное состояние ВНС и ФПК, положительно влияет на течение беременности, родов и состояние плода и новорожденного.

Ключевые слова: преконцепционная подготовка, беременность, профилактика гестоза, комплекс витаминов и минералов.

 

 

Veropotvelyan P. N., Veropotvelyan N. P., Goruk P. S., Pogulay J. S., Zavgorodnyaya L. I.

Rational approach to using lymphocytotherapy in case of a habitual preg-nancy incompetence.

130

The overview of literature and own data results on the role of immune factors in the habitual pregnancy in-competence development are given. The article states that the effectiveness of lymphocytotherapy depends on an appropriate selection of patients on the basis of their anamnesis and molecular-genetic tests. Various mechanisms of the method’s effect are shown.

Key words: habitual pregnancy incompetence, lymphocytotherapy.

 

 

Golyanovskiy O. V., Mekhedko V. V., Galich I. D., Bachyns’ka M. A.

Modern methods of isthmic-cervical insufficiency.

134

The review of literature by the authors provides basic information on the issue of miscarriage associated with isthmic-cervical insufficiency (ICI). The article detailed the etiology, pathogenesis and risk factors that predis-pose to the emergence of ICI. With the current position the issues of diagnosis and treatment of ICI as the outside of pregnancy, and during its progression were considered. Paying special attention to the surgical methods of correction, use of midwifery pessary handling and medical support after surgical treatments for ICI.

Key words: miscarriage, isthmic-cervical insufficiency, obstetric discharge pessary, mersilenic strip.

 

 

Tutchenko L. I., Mellina I. M., Hamolya A. A., Gorelaya E. M., Mitkova E. M.

Features of lipid metabolism in pregnant women with hypertension and obesity.

140

The results of lipid abnormalities in pregnant women with hypertension and obesity are represented in the article. The study found the presence of severe dyslipidemia in women with hypertension as a concomitant of obesity, and without such. In particular, revealed a significant decrease of HDL-cholesterol and increased of atherogenicity coefficient in all the examined pregnant women with hypertension. At the same time, the most pronounced changes in lipid metabolism were found in women with hypertension and concomitant obesity, especially in the second half of pregnancy: a significant increase in serum concentrations of total cholesterol, triglycerides and a significant reduction of HDL-choles- terol. The data should be considered when develo-ping advanced complex of treatment and prevention measures in these patients.

Key words: pregnant, hypertension, obesity, lipid metabolism.

 

 

Semochkin S. V.

А clinical efficacy of Tot’hema in the treatment of iron deficiency anemia in adults: hematologic response and improvement in quality of life.

143

Tot’hema® is the modern drug of ferrous iron is widely used in Russia. The purpose of this study was to in-vestigate the clinical efficacy and tolerability of this drug. Own experience of using Tot’hema® in the treat-ment of iron deficiency anemia in adults is presented in this article. The analysis includes an assessment of the frequency of hematologic response and frequency and severity of adverse events and improves quality of life parameters.

Key words: Tot’hema®, ferric gluconate, iron deficiency anemia, quality of life, SF-36 questionnaire.

 

 

Подольський В. В., Дронова В. Л., Теслюк Р. С., Подольський Вл. В.

Особливості медико-соціального впливу впровадження сучасних ме-дичних технологій на покращання репродуктивного здоров’я жінок із запальними захворюваннями статевих органів.

148

 

 

Резніченко Г. І., Резніченко Н. Ю.

Застосування препарату Актовегін для корекції вегетативних дисфун-кцій та якості життя у пацієнтів старшого віку.

151

Вивчено ефективність застосування Актовегіну для лікування вегетативних дисфункцій і поліпшення якості життя в пацієнтів старшого віку. Установлено, що лікування Актовегіном забезпечує нормалі-зацію функціонування вегетативної нервової системи й міокарда, гемодинаміки головного мозку, доз-воляє поліпшити якість життя пацієнтів старшого віку.

Ключові слова: вегетативна дисфункція, якість життя, Актовегін.

 

 

Markin L. B., Shatylovytch K. L.

Assessment of efficiency of the usage of didrogesteron at the presence of idiopathic threatening abortion.

154

Carry out researches showed that gestagen Duphaston normalizes uterine activity, positively influences gestational transformation of preplacental blood flow, provides an expressed clinical effect after 2-weeks therapy in 92% cases of idiopathic threatening abortion.

Key words: idiopathic threatening abortion, didrogesteron (Duphaston).

 

 

Ganzhiy I. U.

State of reproductive health for women with the polycystic ovary synd-rome.

157

In the study was analyzed the gynecologic anamnesis peculiarities in women of different age groups with polycystic ovary syndrome (PCOS). Authors have founded that these women more often have puberty dis-turbances, primarily manifested in early pubarche, as well as weight gain during this period. In addition was recorded high frequency of other gynecologic pathology. Based on the findings, the authors concluded that age has an effect only on that part of gynecological anamnesis, which relates directly to diseases of genital organs, while other components reflect the state of social environment.

Key words: polycystic ovary syndrome, gynecologic anamnesis, contraception, puberty, sexual life.

 

 

Подзолкова Н. М., Никитина Т. И.

Применение сертаконазола у женщин с рецидивирующим кандидоз-ным вульвовагинитом.

160

 

 

Подольський В. В., Хомінська З. Б., Штул І. А.

Рівень тиреотропного гормону та тироксину в крові жінок з фоновою патологією шийки матки репродуктивного віку, що мешкають у регі-оні з природним йододефіцитом.

164

 

 

Gopchuk E. N.

The aspects of correction dishormonal violations of reproductive system in women.

166

The article touched upon the prevention and treatment of menstrual disorders in women of reproductive age on the background of thyroid disease and iodine deffitsita. Given the prevalence of conditions, the prevention of iodine deficiency is becoming a national issue. Combined application of iodine (Yodofol) is regarded as one of the solutions to identified problem.

Key words: Yodofol, prevention, treatment, menstrual disorders, iodine.

 

 

Дубчак А. Є., Лук’янова І. С., Мандзій І. М.

Стан тазової гемодинаміки у жінок з безплідністю, яка супроводжу-ється хронічним тазовим болем.

169

Проведено ультрасонографічне та допплєрометричне дослідження 50 жінок з безплідністю на фоні ХТБ та 20 жінок з безплідністю без ХТБ. У 92% жінок з безплідністю та ХТБ виявлені структурні зміни органів малого таза. У жінок з безплідністю на фоні ХТБ виявлено розширення вен параметрія, діа-метра маткової вени, що свідчить про значні судинні ураження. Допплєрометричні показники швидкос-тей кровотоку свідчать про його порушення в маткових та яєчникових артеріях.

Ключові слова: безплідність, хронічний тазовий біль, тазова гемодинаміка.

 

 

Romanenko Т., Ignatuk Т.

Prophylaxis of placental disfunction of infectious genesis.

172

The results of use of the Mycogynax and Utrogestan with the purpose of prophylaxis of placental disfunction of infectious genesis for pregnant of group of high risk it’s development are presented in the article. We have inspected 100 pregnant of group of high risk on development of placenta insufficiency and 50 practically he-althy pregnants. It is set as a result of the conducted researches, that forming and functional state of fetop-lacental complex for pregnant of group of high risk of placenta insufficiency caused by infection, characteri-zed by the considerable level of violations of the functional state of foetus, placentas, amounts of amniotic fluid, on a background the expressed haemodynamic and endocrinology violations. During a gestational pro-cess these pregnant have the state of microbiocenosis of genital tracts, characterized by the progressive decline of amount of lactobacterium, bifidobacterium on a background the simultaneous increase of stamms of staphylococcus and other pathological microorganisms (ureo- and mycoplasms, chlamydia, escherichia, proteus). The use of offered medical and preventive methods allow to reduce frequency of placenta insuffi-ciency, delay of height of featues, acute urogenital infection, bacterial vaginosis.

Key words: placenta insufficiency, infection and pregnancy, endocrine function of fetoplacental complex, microbiocenosis of genital tracts, utrogestan, Mycogynax, prophylaxis of placenta insufficiency.

 

 

Подольський Вл. В.

Гормональні характеристики менструального циклу в жінок із хроні-чними запальними захворюваннями статевих органів залежно від типу статевої конституції.

177

 

 

Gavrushov D. N.

Perinatal outcome with asymptomatic bacteriuria of urinary tracts ac-cording to the degree of bacteriuria.

181

The article describes the comparative analysis of pregnancy outcomes, peculiarities of delivery and the pos-tnatal period of 137 women with different degrees of asymptomatic bacteriuria of urinary tracts and of 45 healthy women. It has been registered that the asymptomatic bacteriuria increases the number of premature labor, abnormal labor, premature moving of amniotic fluid and surgical delivery. Women with the untreated moderate bacteriuria had postnatal complications such as purulent inflammatory processes 2.8 times more often than women with the evident bacteriuria.

Key words: asymptomatic bacteriuria, perinatal complications, pregnancy, premature delivery, cesarean section, puerperium.

 

 

Hetsko N. V.

The pecularities of the vaginal biocenosis at pregnants with oncogenical high risk human papillomavirus.

185

In article the results of vaginal biocenosis investigation with HPV are discussed in article. The violation of normal vaginal biocenosis, complications of pregnancy, childbirth, puerperal and neonatal period are dis-played.

Key words: vaginal biocenosis, pregnancy, oncogenic high risk papillomavirus.

 

 

Markyn L., Shakhova E.

Efficiency of application of combination of different pharmaceutical forms of antiseptic Hexycon wich has antimicrobial activity at the treat-ment of inflammatory diseases of vagina.

188

Efficiency of application of combination of different pharmaceutical forms of Hexycon at the treatment of inflammatory diseases of vagina was examined. It was proved that the usage of combination of vaginal solution+vaginal suppositories of Hexycon per night during the first 3th days of treatment and one vaginal suppository per night during subsequent 7th days provides the expressed clinical effect at therap of nonspecific vaginitis.

Key words: Hexycon, vaginitis.

 

 

Kaluzhna L. D., Bardova K.

The modern aspects for appointment protivotrihomonadnyh treatment in women.

192

This article represented that metronidazole vaginal increases the effect of oral administration, prevents recur-rences

Key words: trichomoniasis, bacterial vaginosis, metronidazole.

 

 

Абдуллаева Л. М.

Клинико-гистологическая характеристика доброкачественных обра-зований яичников.

197

 

 

Hourani I. F.

Spiral computer tomography in effectiveness evaluation of protective therapy in post chemo-radiation therapy pulmonary demages in patients with breast cancer.

199

The role of spiral CT in the detection of post сhemo-radiation damages of the respiratory system was studi-ed. It was found that chemo-radiation therapy leads to damage of the respiratory system in 76,7% of pati-ents. Bronchitis and pulmonitis develop within first 3 months in 63,4%, pneumosclerosis and fibrosis of the lungs develop during the first year – in 32,4%. Quercitin and thiotriazolinum weaken harmful effect of chemo-radiation therapy on lung tissue, it allows to make the number of bronchitis and pulmonitis 6-7 times less, prevent the development of pulmonary fibrosis, reduce inflammation in lungs, improve indices of external respiration. Spiral CT allows to detaile semiotics of post сhemo-radiation damages, identify early damage symptoms of bronchus and lung tissue.

Key words: spiral computer tomography (spiral CT), pulmonary complications of chemo-radiation therapy, quercitin, thiotriazolinum.

 

 

Проклятие Евы.

202

 

 

Toryanik E. L., Saharova T. S.

Status of embryo- and fetogenesis by serotonin placental dysfunction in female rats on a background of hypertension.

204

The paper presents the results of the study status of embryo- and fetogenesis by serotonin placental dys-function in female rats on a background of hypertension. Found that hypertension in SHR female rats during pregnancy complicated by what appears an inflammatory reaction in the lumen of uterine glands, fuller ves-sel, partially filled with vessels of the labyrinth placenta and uterus aggregated erythrocytes. Placental sero-tonin dysfunction in pregnant SHR female rats causes obliteration of the uterine vessels and connective tis-sue cells of the placenta, and makes them not functional. Pregnancy in SHR female rats, complicated by pla-cental dysfunction, increased postimplantation loss and affects the viability of fetuses.

Key words: embryogenesis, fetogenesis, serotonin placental dysfunction, hypertension.