HEALTH OF WOMAN WH_№1_2014
Nazarenko L., Dubrova L.
Actual aspects of pregnancy and childbirth in women with a history of cesarean incision (Review).
Presents an analysis of published data concerning gestation in women who underwent cesarean delivery in the past. The data on the frequency of complications at reoperation, the benefits of a vaginal birth, the factors that affect the success of attempts at delivery, evaluation criteria state scar morphology of the lower value segment operated uterine differences lactation.
Key words: pregnancy complications, birth, cesarean section.
Инновационный контрацептив Джайдес® обеспечивает женщине контрацептивную защиту на период до трех лет.
На фармацевтическом рынке Украины появилось инновационное средство долгосрочной контрацепции, обеспечивающее высокоэффективную обратимую защиту от нежелательной беременности на период до трех лет. Джайдес® (ЛНГ-ВМС 13,5 мг), самая маленькая гормональная внутриматочная система (ВМС), представляет собой новую привлекательную опцию для женщин, которые хотят избежать ежедневной, еженедельной или ежемесячной рутины применения контрацептивов. Система Джайдес® одобрена Государственным Экспертным Центром МОЗ Украины 02.10.2013 года в качестве средства, обеспечивающего надежный контрацептивный эффект в течение 3 лет.
Он-лайн площадка по обмену знаниями для врачей.
20th International FIGO Congress. Congress overview.
In October 2012 in Rome was held a Congress of the International Federation of Gynecology and Obstetrics (FIGO), in which the expert meeting held in parallel of experts on the obstetrics and reproduction-problems, the latest data and innovative approaches and tactics of the most topical treatment of pathologies. The expert meeting was attended by leading international obstetricians from around the world (UK, USA, Italy,and Belgium). The present review describes some of the papers devoted to the problem of premature birth and the use of local natural progesterone with a view to their prevention, as well as to reduce neonatal morbidity.
Key words: reproductology, prematurity, neonatal outcomes, progesterone, Utrogestan.
Новые горизонты эндоскопической хирургии: новые знания расширяют границы.
Стратегія розвитку акушерсько-гінекологічної допомоги в умовах реформування акушерсько-гінекологічної служби міста Києва.
Zhylka N. Y.
Main features feminization of HIV infection as problem epidemic in Ukraine.
The basic factors of feminisation of HIV and provided strategic direction for prevention HIV infection in women, effects on the suspension of the HIV epidemic in Ukraine.
Key words: HIV, women, children, epidemic, strategy, feminization.
Makarenko M. V., Govseev D. A., Bereza A. A., Pershinа T. B.
Modern views on the training of pregnant women and their families to childbirth.
The modern views on the training of pregnant women and their families to childbirth have been analized. Training of pregnant women for childbirth gives possibility for physiological pregnancy and childbirth in women.
Key words: pregnancy, childbirth, the neocortex, the current views on the preparation for childbirth, obstetrician-gynecologist, psychological support, a midwife.
Оценка переносимости природного прогестерона, вводимого интравагинально, во время I триместра беременности.
Uterine Sarcoma in the World.
Uterine Sarcoma (US) is a rare cancer with an estimated worldwide incidence rate of 1,55–1,95 per 100 000 and comprises less than 5% of all the uterine corpus malignancies. US is a sophisticated topic to study on. It should be always born in mind that the final diagnosis of a uterine myoma patients could be sarcoma.
Key words: Uterine Sarcoma, incidence rate, final diagnosis.
Romanenko T. G., Melnychuk I. P.
Cervical incompetence: diagnosis, the management of pregnancy, correction methods (аnalytical review of the scientific literature).
The results of the analytical review of the scientific literature on issues related to miscarriage during cervical incompetence. The principles pregravidal training for women at high risk for miscarriage with cervical insuffiency. Highlight the major methods at diagnosis and correction cervical incompetence.
Key words: miscarriage, cervical incompetence, midwifery pessary, transvaginal ultrasound scan.
Монахов С. А.
Новые возможности в антиандрогенной терапии акне у женщин.
Описан метаболизм половых стероидов в организме женщины. Рассмотрен этиопатогенетический подход к терапии акне с использованием комбинированных оральных контрацептивов Джаз и Джаз Плюс.
Ключевые слова: гиперандрогения, акне, дроспиренон, фолиевая кислота, метафолин.
Bobrytska V. V., Grischenko O. V., Korovay S. V., Chernyak O. L.
New word in the treatment of atrophic kolpit.
Under a supervision there were 65 women 40–55 years old with atrophic kolpit, 45 persons from them, having contra-indication to replace estrogen therapy, were got vaginal suppositories with hyaluronic acid Revitaxa®; 20 patients, got nosotropic therapy of suppositories with estrogen and antiseptic. Clinical effects of suppositories Revitaxa® compleetly related to the pharmacy with the nosotropic action – estrogen in combination with antibacterial therapy of local atrophic changes.
Key words: atrophic kolpit, phytosuppositories, hyaluronic acid, Revitaxa®.
Danylko V. A., Islamova E. V.
Urinary tract infection during pregnancy: diagnostic features, treatment, and new prevention opportunities.
The article presents features of the course and diagnosis of urinary tract infections among pregnant women, and the factors that caurse their development. The modern methods of treatment for asymptomatic bacteriuria, acute cystitis, acute pyelonephritis are demonstrated in this article, as well as new opportunities to prevent them. The article shows a significant increase in the effectiveness of the treatment and prevention of many nephrology diseases, especially infectious diseases, through usage of phytopreparation Nephrocare.
Key words: pregnancy , urinary tract infection , therapy, prevention, Nephrocare.
Davydova Yu. V., Voronkov L. G., Ogorodnik А. O., Pashynny A. V., Mokryk А. N., Butenko L. P.
Iron deficiency and its correction in pregnant women having heart failure.
In the article are reviewed modern approaches related to evaluation of iron storage and its correction methods in pregnant women with heart failure associated with apparent cardiovascular pathologies. Obtained results reflect reasonability of a transferrin saturation index research and a soluble receptor to the transferrin, allowing to avoid a trigger mechanism when develop severe perinatal and cardiac complications as a result of the iron deficiency in a group of women with high perinatal risk, to which women with congenital heart diseases and heart failure refer.
Key words: pregnancy, congenital heart diseases, heart failure, iron deficiency, soluble transferrin receptor.
Zabolotnov V. A., Ribalka A. N., Lyashenko E. N., Kamilova I. K., Kosolapova N. V.
Menstrual disorders, gradual therapy.
The paper presents the modern terminology, classification of menstrual disorders and it’s component – abnormal uterine bleeding by The International Federation of Gynecology and Obstetrics (FIGO). The gradual scheme of therapy for menstrual disorders is referred with phytotherapy, based on the prostrate summer cypress ordinary extract, occupies a special place.
Key words: abnormal uterine bleeding, phytotherapy.
Ventskivskyy B., Vitrenko D.
Changes in reproductive health women depending on method of cesarean section and category urhentnosti.
The article presents information on changes in women's reproductive health, depending on the method of cesarean section and the category urhentnosti evaluated their results. Feeling depressed marks every fifth woman who held a c-section. The process of lactation is stored in 82,07% women. Changes in sexual life is celebrated 59.43% of patients. After the surgery pathology noted by Stark 53,62% of the women in Gusakova – 66,67%, while in Derfleru – 92,31%. After primary cesarean sexual dysfunction found in 50,63% of cases, and with repeated – often – 85,18%. After primary cesarean violations detected in 29,11% of cases, and with repeated – often – 70,37%.
Key words: сesarean section, category urhentnosti, reproductive health.
Telychko L. V.
Modern methods of diagnostics of placenta disfunction in case of polyfoetus pregnancy.
Multiple pregnancy complicated by plancental dysfunction increases the risk of maternity and prenatal morbidity and mortality and needs the development of effective preventive measures and treatment of these complications. The usage of integrated ultrasonic scanning with three-dimensional ultrasound for the first time shows hemodynamic features of formation of «mother-placenta-fetus» in I-st trimester of pregnancy with physiological course of pregnancy and in the presence of placental dysfunction in multiple pregnancy. The criteria that can predict pregnancy complications is defined; it is placental dysfunction, based on indicators volume blood flow in the chorion at multiple pregnancy. In our opinion the most important task of modern obstetrics is antenatal care in pregnancy, which in the overall program leads to the protection of future generations.
Key words: multiple pregnancy, plancental dysfunction, chorion volume, vascularization index.
Tolstanova G. A., Golyanovskyi O. V.
Predicting criteria of intrauterine growth retardation syndrome.
This article presents a study of the most prognostic significant risk factors for IUGR, determined the effect of each on the likelihood of IUGR, studied diagnostic information of clinical signs, which were used in the prediction of IUGR during pregnancy. We have developed a mathematical model of the likelihood of IUGR from the scores of risk factors, as well as to determine the sensitivity and specificity of the prediction model and found the relative risk for IUGR.
Key words: pregnancy, intrauterine growth retardation, risk factors, prognostic model, chronic fetoplacental insufficiency.
Yanyuta А. S., Yanyuta G. S.
During childbirth, condition of fetus and newborn for pregnant with gestation diabetes.
This article consists the own date about during pregnancy, outcome of labor, condition of fetus and newborn for pregnant with gestation diabetes. The received results allow timely change of tactics of conducting pregnancy and sorts for purpose of frequency decrease perinatal pathology.
Key words: pregnancy, gestation diabetes, outcome of labor, condition of fetus, newborn.
Vdovychenko Yu. P., Ishchak O. M., Franchuk A. Yu.
Effect of varicose vein disease of the lower extremities by pregnant on occurrence of perinatal and obstetric complications.
In this article there are given the research data, which provided an opportunity to find out population frequency of the pregnant women with varicose vein disease of the lower extremities and with the signs of connective tissue dysplasia, to determine the state of the connective tissue on the collagen metabolism indices by pregnant, to find associative connections of the connective tissue dysplasia syndrome and varicose vein disease of the lower extremities with the pathological pregnancy and childbirth; formation of perinatal and obstetric complications, neonatal susceptibility to disorders of neonatal adaptation.
Key words: recurrent pregnancy loss, obstetric and perinatal complications, varicose vein disease of the lower extremities, connective tissue dysplasia, oxyproline.
Duda A. K., Kolesnik R. A., Dushak E. N., Vovk I. E., Didych T. V., Dejneka A. M.
Leptospirosis in pregnancy: pathogenesis, clinical features and treatment approaches.
Leptospirosis – a zoonotic disease, which is of global importance. Despite the small number of reports of leptospirosis in pregnant women, this problem is quite relevant, as evidenced by the fairly high prevalence of the disease in Ukraine. Basically leptospirosis infection in pregnant women is accompanied by development erased ( ILI ) or lung anicteric forms and ends recovery. But in some cases develop icteric forms that are characterized by multiorgan failure and may end intrauterine fetal death. Clinico-epidemiological diagnosis is based on history, objective and laboratory and instrumental examination, confirmed by polymerase chain reaction. The main focus of treatment is appropriate and timely antibiotic therapy. Question delivery medically must be solved together obstetrician, infectious diseases and, if necessary, the proprietary nature of other doctors. Thus it is necessary to consider the gestational age, severity of disease, the risks for mother and child.
Key words: leptospirosis, pregnancy, antibiotikoteraiya, delivery was medically indicated.
Trohimovych O. V.
Microbiocenosis of genital tract in women with early pregnancy losses.
The condition of the genital tract microbiocenosis of 20 women with miscarriage and 44 women with missed abortion in terms of 4–12 weeks of pregnancy was studied. An active contamination of the vagina of two- and three;way associations of opportunistic pathogens, the increasing detection rate of sexually transmitted infections and the significant deficit of lactobacillus was registered. Increased microbial contamination of the genital tract of women with early pregnancy loss suggests that inflammation plays a major role in the etiopathogenesis of reproductive losses.
Key words: early pregnancy losses, microbiocenosis.
Nagornaya V. F.
Еndogenous progesterone and progestins in physiological pregnancy, prevention and treatment of its complications.
Progesterone has the main role in the mechanisms of successful pregnancy. In obstetric practice to support the pregnancy with a deficit of progesterone progestins are used (progesterone analogues). In, obstetric practices in Ukraine progesterone, micronized progesterone, dydrogesterone are used. Analysis of long-term results of administration of progestogens during pregnancy, enduring the criteria of evidence-based medicine, was performed only for dydrogesterone. The main indication for the dydrogesterone use in obstetric practice is a treatment and prevention of miscarriages.
Key words: pregnancy, miscarriage, progesterone, dydrogesterone.
Veropotvelyan P. N., Guzhevskaya I. V., Veropotvelyan N. P., Narytnik T. T.
Importance of vascular endothelial growth factor for the formation of normal fetoplacental angiogenesis in pregnant.
Important role of the vascular endothelial growth factor for the formation of normal fetoplacental angiogenesis in pregnant women has been presented. Findings of many publications regarding vascularization of placenta villi at various gestation periods have been analyzed. The role of vascular endothelial growth factor and that of its receptors in angiogenesis and vasculogenesis of placenta has been studied. Proper vasculogenesis and angiogenesis in placenta depend on the balanced interaction of angiogenic factors, the family of vascular endothelial growth factor occupying a priority position among them.
Key words: angiogenesis, placenta, vascular endothelial growth factor, receptors of the vascular endothelial growth factor.
Onusyko O. V.
The state of placenta and fetus complex in pregnant woman wich have insylin resistance.
In this article features of violations of placenta complex in pregnant woman with insylin resistance and their influence on further motion of pregnancy are considered. The retrospective clinical and statistical analysis of 100 individual cards and histories of births for patients with the policystic ovary syndrome on a background of insylin rsistance is conducted . It is set that insylin rsistance causes many complications during pregnancy, related to placental disfunction.
Key words: pregnancy, fetus, placenta, insylin resistance.
Абакарова П. Р.
Опыт применения препарата Полижинакс при лечении неспецифических и смешанных вульвовагинитов.
Прилепская В. Н., Бебенева Т. Н.
Возможности терапии мастодинии с применением микронизированного прогестерона.
Veropotvelyan P. N., Narytnik Т. Т., Veropotvelyan N. P., Guzhevskaya I. V., Kravtsova O. M.
Sexual and psychological dysfunction in couples in some endocrine inflammatory genital diseases and their correction.
A review of the literature and our own research suggests that patients with chronic endometritis relatively frequent violation and 61.7% of the partners sperm observed sexual dysfunction. When endocrine diseases: polycystic ovarian syndrome with pituitary ovarian failure with hyperprolactinemia – registered sexual dysfunction ranging from 77,7% to 88,5%. At the same pathogenesis sexual function affects by psychological background neurohormonal changes and disruption of interpersonal relationships in marriage. Application Tribestan in combination with antimicrobial agents more effective in treating inflammation of the uterus, which provide clinical improvement of patients and normalization function allows the state of the autonomic nervous system. Therapy held in conjunction with Tribestanom enables significant improvement in the cardinal factors of sexual health. In 77% of patients of the second group compared with 39,7% of patients first. Semen improved by 67,7% in the second group, and in the first it was –31,7%. Outcomes improves quality of patients in fertile age life and their partners.
Key words: chronic endometritis (CE), polycystic ovaries, uretroprostatit, drug Tribestan.
Potapov V. A., Pyrohova V. I., Kornatska A. G., Lytvinuyk S. I.
Preparing for small remedial gynecological surgery.
In this paper we present a contemporary strategy of preoperative antibiotic prophylaxis before small gynecological operations. Expand the arsenal of small gynecological operations on female genital mutilation, which now account for the structure of surgical activity obstetrician – gynecologist to 70–80%, moving the majority of surgical procedures in the outpatient «one-day hospital», the emergence of office minimally invasive endoscopic technologies increases the urgency of protection against contamination of infections area of surgical intervention. Inflammatory complications after surgery on small genitals, the frequency of which varies from 5% to 23%, associated not only with organizational problems of aseptic and antiseptic, but also medical and biological aspects of them. Increasingly, the cause of postoperative infectious and inflammatory complications after surgery on small genitals are not unconditional pathogens (gonococcus, chlamydia, trichomonas), and conditionally pathogenic flora, which normally is a component of the ecosystem of the reproductive tract. Due to violations under the influence of external and internal factors for biocenosis environment often becomes dominant with the formation of a pool of usually mixed infections. Known difficulties of laboratory diagnosis flora imbalance and complexity of the reproductive tract in the selection of antimicrobial agents for the corrections of such conditions have now become the basis for the formation of the modern concept of empirical medical prophylaxis of infection preoperatively using local complex of antimicrobials with a broad spectrum of action. The paper presents the experience of use for the prevention of infection in local comprehensive preoperative antimicrobials with a broad spectrum of action (cover all possible causative agents of genital infections), such as Neotrizol and Ofor, antimicrobial spectrum in which 87–90% of cases lead to the elimination of redundant microbial pools restore vaginal biotope and effectively prevents the development of postoperative infectious complications.
Key words: small gynecological surgery, postoperative infectious-inflammatory complications, prevents the development of postoperative infectious complications, complex antimicrobials Neotrizol and Ofor.
Zaykovа T. V.
Model of comprehensive cervical cancer prevention.
Рresents an analysis of the components of an effective comprehensive prevention of cervical cancer (CC) in order to identify ways to achieve a positive impact on reducing the incidence of cervical cancer. In the course of the study used a descriptive method of simulation in order to justify and develop organizational model integrated cervical cancer prevention method organizing and experiment for his approbation. Analysis of the current situation in Ukraine on the prevention of cervical cancer showed that the main obstacles to the use of effective prevention technologies is the lack of awareness on the prevention of STIs and the vaccine, the absence of state provision decreed populations HPV vaccine, opportunistic type checkups, personnel and technological crisis in cytological service. The proposed functional and organizational model of the complex effective prevention of cervical cancer structurally divided into primary and secondary prevention, which introduced components of the national health system improvements to organizational and clinical, diagnostic technologies.
Key words: сervical cancer, infections, sexually transmitted diseases, prevention.
Оrazov М. R.
Impairment of fertility in women with pain syndrome of adenomyosis.
The article is devoted to one of the most pressing problems of women of reproductive age – the problem of pelvic pain adenomyosis. Frequency of adenomyosis, according to the data of different researchers varies from 12 to 40% of women of fertile age. In the structure of female infertility adenomyosis takes 18–26%. The aim of research was to study the clinical and anamnestic descriptions of the factors of impairment of fertility in women with pain syndrome of adenomyosis. The study involved 32 women with chronic pelvic pain syndrome adenomyosis – as a core group of 10 patients without painful form of adenomyosis constituted the group of comparison. Results of the study showed the important role of the complex mechanisms of the Genesis of infertility with the involvement of several factors, on the background of chronic pelvic pain syndrome adenomyosis that, you need to consider in selecting pathogenetically substantiated therapy of infertility.
Key words: infertility, adenomyosis, pain treatment.
Maievska I. O., Dubchak A. E.
Characteristics of reproductive system pathology in women-liquidators of the Chernobyl nuclear accident in 1986–1987 over the 25 years after the accident.
There were examined 333 women;liquidators of the Chernobyl nuclear accident (1986–1987) in 1994–2007 гг and diagnosed the characteristics of reproductive system pathology depending on external irradiation doses of the entire body.
Key words: women-liquidators of the nuclear accident, reproductive system diseases, external irradiation doses.
Kornatskаyа А., Danilenko Н., Flaхemberg М.
Prevention of complications of pregnancy that does not develop.
To reproductive losses belongs miscarriage as a significant medical and social problem, with a frequency that is stable and quite high, ranging from 2% to 55% and in the first trimester of reaching 80%. As part miscarriage is a pregnancy that is not developing its frequency, according to different authors, is more than 20% of all pregnancies are desired. The purpose of the given research is to improve methods of preparation sexual ways to the termination of missed pregnancy through their rehabilitation using drugs which contain an iod. The use of ultrasound examination of dopplerometry mapping made it possible to establish diagnosis of missed pregnancy. Conducted a comprehensive study biocenosis of genital tract and conducted training of drugs which contain an iod to prevent complications. The obtained results allow to assert that biocenosis of vagina in women with missed pregnancy, for the most part, characterized by the association of pathogenic microorganisms, and the use of drugs which contain an iod rehabilitation, helps prevent the development of complications.
Key words: pregnancy not developing opportunistic pathohenic microflora, prevention of complications.
Dubchak A., Milievskyi A., Dovgan E.
Immunotherapy in treatment of inflammatory diseases of the internal genital organs.
Studied parameters of local immunity in 48 women with tubal- peritoneal infertility by chronic inflammation of internal genital organs. The changes in the status of local immunity of the women surveyed in the course of treatment. The role of immunotherapy (Laferobion) in the treatment of inflammatory diseases of the internal genital organs.
Key words: inflammatory diseases of the internal genital organs, infertility, local immunity, immunotherapy.
Senchuk S., Savrun V., Samsonova I., Doskoch I., Chermak І.
Prevention of inflammatory complications and recurrence of cervical diseases after surgical treatment.
A comprehensive examination of 100 patients with chronic adnexitis was conducted to enhance the effectiveness of surgical treatment and prevent the recurrence of precancerous diseases of the cervix. The results allowed us to develop pathogenesis-based approach to managing postoperative period, which includes the prescription of anti-inflammatory drugs Dystreptaza which have fibrinolytic and antithrombotic activity, and vaginal swabs Ellen, that contain probiotics. Comprehensive patient’s examination in 3 months after surgical treatment of cervical pathology showed that the effectiveness (elimination of HPV, absence of colposcopic and cytological signs of cervical dysplasia, absence of ultrasound and dopplerometry salpingoophoritis signs) of complex therapy, including surgical treatment of dysplasia focus and prescription of conservative therapy using rectal suppositories Dystreptaza and probiotic Ellen in patients with precancerous cervix diseases on the background of chronic salpingoophoritis, is 96.0 %.
Key words: cervical dysplasia, chronic salpingoophoritis, treatment.
Gynchitcka L. V.
Clinico-hormonal characteristics of women with endometriosis and infertility.
The paper presents the results of investigation of prolactin, LH,FSH, tyroid hormones, TSH, estradiol, cortisol and androgen levels in 37 women with external genital endometriosis and infertility (15 healthy women were in control group). It has been revealed that in the examined patients side by side with genital endometriosis hyperprolactinemia, hyperandrogenia, and progesteron deficiency have significant influence.
Key words: endometriosis, infertility, hyperandrogenia.
Shevchenko A. A.
Congenital malformations of the central nervous system: prevalence and structure (retrospestive study). Aspects of prenatal diagnostics.
This work presents the prevalence and structure of congenital anomalies of the CNS by analyzing 115 case histories of children which examined and treated at the department of children's psychoneurology of the SI «Institute of pediatrics, obstetrics and gynecology of the National academy of medical sciences of Ukraine» from 2008 to 2012 (retrospective study). There were described the data on the various features of the prenatal diagnosis of different CNS anomalies depending on the timing of gestation. It was grounded the benefit of the use of the efficiency of the method of MRI during pregnancy for improvement of prenatal diagnostics and subsequent clinical and prognostic assessment.
Key words: congenital anomalies, central nervous system, retrospective study, prenatal diagnostics.
Tovstanovska V., Cruk O., Basenko I. O., Kusch V. N.
Clinical and morphological features papilomavirusnoy infection in inflammatory diseases of the genital and dysplastic young women of reproductive age and modern diagnostic methods for pre-clinical and early clinical stage.
Clinical and morphological conducted clinical studies demonstrate the following impact on the development of PVCH infection and inflammatory diseases of the genital organs of dysplastic and progression CIN in women of reproductive age early . The methods of modern diagnostics that can be used to perform early diagnosis of CIN and prevent the development of pathological processes in the early clinical and pre-clinical stages.
Key words: human papillomavirus, an inflammatory disease, cervical dysplasia, diagnostics, precancer and cancer of the cervix.
Научное акушерство: из прошлого в будуще.