• Probiotic strains Lactobacillus acidophilus R0052 and Lactobacillus rhamnosus R0011 in the evolution of antibiotic-associated diarrhea in children with burn injury
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Probiotic strains Lactobacillus acidophilus R0052 and Lactobacillus rhamnosus R0011 in the evolution of antibiotic-associated diarrhea in children with burn injury

SOVREMENNAYA PEDIATRIYA. 2015.2(66):102-104; doi 10.15574/SP.2015.66.102

Probiotic strains Lactobacillus acidophilus R0052 and Lactobacillus rhamnosus R0011 in the evolution of antibiotic-associated diarrhea in children with burn injury

Skripnikova Ya. S., Ivan'ko O. G., Patsera M. V., Ponomarenko E. V., Radutnaya E. A. 
Zaporizhzhya State Medical University, Ukraine

Objective. To examine the incidence, characteristics of the course and possible prevention of antibiotic-associated diarrhea (AAD) in burn patients.

Patients and methods. A total of 452 children with burn injuries who had received antibiotics were under observation for the period from 2010 to 2014yy. in the regional burns unit department of Zaporizhzhya.

Results. In the setting of the treatment of burn injuries the AAD of varying severity was found in 8.6–24% of children. In 76% of children AAD accompanied by the release of pathogenic toxins Clostridium difficile. The methods for prevention of AAD were developed first of all for the aim of preventive application of oral probiotic containing probiotic strains Lactobacillus acidophilus R0052 and Lactobacillus rhamnosusR0011 from early hospitalization as part of the preparation «Latsidofil®» in the age dosages.

Conclusions. Antibiotic diarrhea is a significant problem of patients of burn department. The use of probiotic preparation «Latsidofil®» in the complex treatment of burn injury decreased the incidence of AAD in three times and reduced the severity of its symptoms. Key words: children, burn injury, antibiotic therapy, antibiotic-associated diarrhea, probiotic strains Lactobacillua cidophilus R0052 and Lactobacillus rhamnosus R0011.

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