• Probiotic correction of functional diseases of the gastrointestinal tract in children

Probiotic correction of functional diseases of the gastrointestinal tract in children

SOVREMENNAYA PEDIATRIYA.2018.4(92):106-110; doi 10.15574/SP.2018.92.106

Shadrin O. H.
SI «Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine», Kyiv

The problem of functional diseases of the gastrointestinal tract (FD GIT) continues to be relevant. In patients with FD GIT, the quality of life and adaptive properties are reduced. To date, a hallmark of the treatment for gastrointestinal diseases is probiotics. The efficacy of probiotics in the prevention of acute gastrointestinal diseases, including using in the neonatal period, antibiotic-associated diarrhea, nosocomial infections, management of various functional disorders of the digestive tract has been proved. In Ukraine, probiotics containing live lyophilized bacteria, namely Bifidobacterium animalis subsp. lactis BB12, are successfully used to treat conditions associated with impaired intestinal microflora composition, including in newborns.
Key words: gastrointestinal tract, functional disease, children, probiotic.

References

1. Andreeva IV. (2011). Sovremennyie dokazatelnyie dannyie effektivnosti primeneniya Lactobacillus rhamnosus GG i Bifidobacterium lactis Bb-12 v pediatricheskoy praktike. Voprosyi sovremennoy pediatrii. 10; 1: 50—57.

2. Shadrin OG, Misnik VP, Ponomareva IG, Klimenko LA. (2014). K voprosu formirovaniya eubioza kishechnika pri iskusstvennom vskarmlivanii detey grudnogo vozrasta. Dytiachyi likar. 1(30): 31—34.

3. Shadrin OH, Platonova OM. (2014, lyp/serp). Osoblyvosti klinichnoho perebihu funktsionalnykh zakhvoriuvan kyshechnyka u ditei shkilnoho viku. Mezhdunarodnyiy zhurnal pediatrii, akusherstva i ginekologii. 1: 65.

4. Chatterjee et al. (2013). Randomised Placebo-controlled Double Blind Multicentric Trial on Efficacy and Safety of Lactobacillus acidophilus LA-5® and Bifidobacterium BB-12® for Prevention of Antibiotic-Associated Diarrhoea. JAPI. 61: 708—712. PMid:24772726

5. Dani C, Biadaioli R, Bertini G. et al. (2002). Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm infants. A prospective double-blind study. Biol Neonate. 82; 2: 103—108. https://doi.org/10.1159/000063096; PMid:12169832

6. Deshpande G, Rao S, Patole S, Bulsara M. (2010). Updated meta-analysis of probiotics for preventing necrotizing enterocolitis in preterm neonates. Pediatrics. 125: 921—930. https://doi.org/10.1542/peds.2009-1301; PMid:20403939

7. Dorte Eskesen et al. (2015). Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12 on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial. British Journal of Nutrition. 114: 1638—1646. https://doi.org/10.1017/S0007114515003347; PMid:26382580 PMCid:PMC4657032

8. El-Salhy M, Ostgaard H, Gundersen D et al. (2012). The role of diet in the pathogenesis and management of irritable bowel syndrome (Review). Int J Mol Med. 29; 5: 723—731. https://doi.org/10.3892/ijmm.2012.926

9. Huertas-Ceballos A, Logan S, Bennett C, Macarthur C. (2009). Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood. Cochrane Database Syst. Rev. 1: CD003019. https://doi.org/10.1002/14651858.CD003019.pub3

10. Johnston BC, Goldenberg JZ, Vandvik PO. (2011). Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst. Rev. 9; 11. https://doi.org/10.1002/14651858.CD004827.pub3; PMid:22071814

11. Kajander et al. (2008). Clinical trial: multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota. Aliment. Pharmacol. Ther. 27: 48—57. https://doi.org/10.1111/j.1365-2036.2007.03542.x; PMid:17919270

12. Larsen et al. (2006). Dose-response study of probiotic bacteria Bifidobacterium animalis subsp lactis BB-12 and Lactobacillus paracasei subsp paracasei CRL-341 in healthy young adults. Eur J Clin Nutr. 60(11): 1284—1293. https://doi.org/10.1038/sj.ejcn.1602450; PMid:16721394

13. Picaud JC, Chapalain V, Paineau D et al. (2010). Incidence of infectious diseases in infants fed follow-on formula containig synbiotics: an observational study. Acta Paediatr. 99: 1695—1700. https://doi.org/10.1111/j.1651-2227.2010.01896.x; PMid:20560895 PMCid:PMC3034191

14. Pitkala et al. (2007). Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial. J Nutr Health Aging. 11: 305—311. PMid:17653486

15. Rautava S, Salminen S, Isolauri E. (2009). Specific probiotics in reducing the risk of acute infections in infancy — a randomised, double-blind, placebo-controlled study. Br J Nutr. 101: 1722—1726. https://doi.org/10.1017/S0007114508116282; PMid:18986600

16. Saavedra JM. (2001). Clinical applications of probiotic agents. Am J Clin Nutr. 73; 6: 1147—1151. https://doi.org/10.1093/ajcn/73.6.1147S; PMid:11393193

17. Savino F, Pelle E, Palumeri E et al. (2007). Lactobacillus reuteri (American Type Culture Collection Strain 55730) Versus Simethicone in the Treatment of Infantile Colic: A Prospective Randomized Study. Pediatrics. 119: 124—130. https://doi.org/10.1542/peds.2006-1222; PMid:17200238

18. Szajewska H, Mrukowicz JZ (2001). Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. J Pediatr Gastroenterol Nutr. 33; 2: 17—25. https://doi.org/10.1097/00005176-200110002-00004

19. Jungersen M, Wind A, Johansen E, Christensen JE, Stuer-Lauridsen B, Eskesen D. (2014, Jun). The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12®. Microorganisms. 2(2): 92—110. https://doi.org/10.3390/microorganisms2020092; PMid:27682233 PMCid:PMC5029483

20. Valles Y, Gosalbes MJ, de Vries LE et al. (2012). Metagenomics and development of the gut microbiota in infants. Clin Microbiol Innfect. 18; 4: 21—26. https://doi.org/10.1111/j.1469-0691.2012.03876.x; PMid:22647043

21. Weizman Z, Asli G, Alsheikh A. (2005). Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents. Pediatrics. 15; 1: 5—921. https://doi.org/10.1542/peds.2004-1815; PMid:15629974

22. Wildt et al. (2006). Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm. Bowel Dis. 12: 395—401. https://doi.org/10.1097/01.MIB.0000218763.99334.49; PMid:16670529