• Obstetric pathology due to humoral rejection 

Obstetric pathology due to humoral rejection 

HEALTH OF WOMAN. 2016.4(110):71–78; doi 10.15574/HW.2016.110.71 

Obstetric pathology due to humoral rejection 

Veropotvelyan Р. N., Veropotvelyan N. P., Tsehmistrenko I. S., Zhuravleva S. A.

The «Inter-provincial center of medical genetics and prenatal diagnosis», Krivoy Rog

Perinatal center, Kiev

In this study was included data of foreign articles and clinical protocols – violation leads to the development of pregnancy pathology, is characterized by the activation of cellular and humoral immune system with the development of clinical manifestations of varying degrees of severity of rejection. The publications expressed the idea of parallels between acute graft rejection, and rejection of the fetus in spontaneous abortion and, in addition, between exclusion and pre-eclampsia.

The cellular mechanisms of rejection of allogeneic transplant or semiallogenic are more studied than humoral in the present period of time. Demonstrated that all types of rejection are with the involvement of different nature antibodies.

Key words: pregnancy, humoral rejection, alloantibodies, autoantibodies, anti-HLA-antibodies, blood group alloantibodies to antigens, embryonic antibodies, agonist antibodies, antiendothelial antibodies.


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