• Myeloproliferative disorders and pregnancy: obstetric and perinatal aspects

Myeloproliferative disorders and pregnancy: obstetric and perinatal aspects

PERINATOLOGY AND PEDIATRIC. UKRAINE. 2018.3(75):52-55; doi 10.15574/PP.2018.75.52

Naumchyk A. N., Davydova Iu. V.
SI «Istitute of Pediatrics, Obstetrics and Gynecology by academician O.M. Lukyanova of NAMS of Ukraine», Kyiv

Objective: to study the management features of pregnant women with myelodysplastic syndrome; to elaborate recommendations on the preconceptional preparation and management of pregnancy in this group of women.

Materials and methods. The data of English$language literature (PubMed, Medline, Cochrane library, Google Search) for 10 years on myeloproliferative disorders, essential thrombocythaemia, and pregnancy have been analysed. In total there were found 230 publications. The most relevant information was obtained from two sources. The content analysis was used.

Results and conclusions. Pregnancy in women with myeloproliferative disorders requires thoughtful planning at the preconceptional stage, pregravid preparation, and also at the stages of pregnancy management, delivery and the postpartum period, considering a substantial number of complications. The most probable complications are thromboembolic ones. The issue of anticoagulant, antiplatelet therapy has been considered.

Key words: myeloproliferative disorders, essential thrombocythaemia, pregnancy.

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Article received: Jun 16, 2018. Accepted for publication: Sep 01, 2018.