• Modern aspects of external anti’inflammatory therapy of atopic dermatitis in children 

Modern aspects of external anti’inflammatory therapy of atopic dermatitis in children 

SOVREMENNAYA PEDIATRIYA.2016.2(74):92-99; doi 10.15574/SP.2016.74.92 

Modern aspects of external anti'inflammatory therapy of atopic dermatitis in children 

Okhotnikova O. M., Yakovleva N. Y., Chernysh Y. R.

National Medical Academy of postgraduate education named after P.L.Shupyk, Kyiv, Ukraine 

Objective: to evaluate the effectiveness and safety of combined use of creams Prednicarbum and synthetic tannin (phenol-methanal-of urea-polycondensate) in the treatment of exacerbation of atopic dermatitis in children. 

Material and methods: 50 children, 1 to 12 years, with atopic dermatitis with the exacerbation of the skin process different degrees of severity.


Results: In children with mild localized form of atopic dermatitis after the monotherapy whith cream synthetic tannin, noted a marked clinical improvement up to 7 days of treatment. The noted expressive positive dynamics of the skin process and reduction of objective symptoms during the first days after of combination treatment with Prednicarbatet cream and synthetic tannin, also after combination therapy Prednicarbate and moisturizing cream in mode of step therapy.


Conclusions: The combined application of Prednicarbate cream and phenol-methanal-of urea-polycondensate increases the effectiveness of anti-inflammatory treatment of atopic dermatitis, which can reduce the duration of use of topical corticosteroids and reduce the risk of adverse reactions in children with moderate and severe course skin process.


Key words: atopic dermatitis, topical corticosteroids Prednicarbate, topical nonsteroidal antiinflammatory drugs (synthetic tannin — phenol-methanal-of urea-polycondensate), children.


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