• Modern approaches to the treatment of arthralgia in children with hypermobility syndrome 
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Modern approaches to the treatment of arthralgia in children with hypermobility syndrome 

SOVREMENNAYA PEDIATRIYA.2014.1(57):59-63; doi 10.15574/SP.2014.57.59 

Modern approaches to the treatment of arthralgia in children with hypermobility syndrome 

Omelchenko L. I., Mukvich E. N., Dudka I. V.

SU «Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine», Kiev 

Objective. To improve the effectiveness and safety of treatment of arthralgia associated with hypermobility syndrome in children. 

Materials and methods. A total of 43 children at the age of 3–18 years with arthralgias associated with hypermobility syndrome were under observation. Within 30 days in the complex treatment children had received «Intsena» preparation according to the age dosage. The condition of patients was assessed by visual analogue scale; clinical examination was carried out. 

Results. During the application of «Intsena» was observed a decrease of intensity and frequency of arthralgia, due to its analgesic and anti-inflammatory effect. Serious side effects of preparation are not found. 

Conclusions. The use of «Intsena» is recommended in the monotherapy and in the complex treatment of children with arthralgia associated with hypermobility syndrome, at the necessity of long-term use of anti-inflammatory maintenance therapy. 

Key words: hypermobility syndrome, arthralgia, children, treatment. 


1. Исаев МР. 2004. Клинико-эпидемиологические особенности гипермобильного синдрома у лиц молодого возраста. Автореф дис канд мед наук. Оренбург: 216.

2. Омельченко ЛИ, Ошлянская ЕА. 2008. Новые возможности аналгезии у детей с гипермобильным синдромом. Здоров'я України. 18: 58—59.

3. Поворознюк ВВ, Подлианова ЕИ. 2012. К вопросу о синдроме гипермобильности суставов. Нов медицины и фармации. 12(422): 33—35.

4. Яременко ОБ, Решотько ОБ, Микитенко АМ. 2006. Новые возможности симптоматической противовоспалительной терапии ревматоидного артрита. Здоров'я України. 17: 2—3.

5. Clinch J, Deere K, Sayers A et al. 2011. Epidemiology of generalized joint laxity (hypermobility) in fourteen-year-old children from the UK: a population-based evaluation. Arthritis Rheum. 63(9)6. 2819—2817.

6. Keer R, Grahame G. 2003. Hypermobility Syndrome — recognition and management for physiotherapists. Philadelphia, PA, Elsevier: 177.

7. Rubio-Agusti I, Kojovic M. 2012. Cervical dystonia and joint hypermobility syndrome: a dangerous combination. Mov Disord. 27(2): 203—204. http://dx.doi.org/10.1002/mds.24013; PMid:22328463

8. Tofts LJ. 2009.The differential diagnosis of children with joint hypermobility: a review of the literature. J Pediatric Rheumatology.