• Modern approaches to the diagnosis of ulcerative colitis in children.
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Modern approaches to the diagnosis of ulcerative colitis in children.

SOVREMENNAYA PEDIATRIYA.2014.3(59):113-115; doi 10.15574/SP.2014.59.113

Modern approaches to the diagnosis of ulcerative colitis in children.

Denisova M. F.

State Institute «Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine »

Abstract. The article discusses current approaches to the diagnosis of ulcerative colitis in children, based on international guidelines, protocols, diagnosis and treatment of inflammatory bowel disease in children Ministry of Ukraine, author's personal experience . The criteria of assessment of disease severity on pediatric activity index, the concentration of faecal calprotectin .

Key words: ulcerative colitis, children, diagnosis, assessment of activity and severity.


1. Яблокова ЕА, Горелов АВ, Ратникова МА и др. 2006. Воспалительные заболевания кишечника у детей. Педиатрия. 5: 99—102.

2. Лукьянова ЕМ, Денисова МФ. 2004. Язвенный колит у детей (клиника, диагностика, лечение). К: 78.

3. Татьянина ОФ, Потапов АС, Намазова ЛС и др. 2008. Маркеры кишечного воспаления при заболеваниях кишечника. Обзор литературы. Педиатрич фармакол. 5;3: 39—45.

4. Захарова ИН, Коровина НА, Копейкин ВН и др. 2009. Современные представления о хронических воспалительных заболеваниях толстой кишки у детей. Часть 1. Вопр практич педиатрии. 4;1: 39—45.

5. Татьянина ОФ, Потапов АС, Намазова ЛС и др. 2008. Фекальный кальпротектин в неинвазивной диагностике воспалительных заболеваний кишечника у детей. Педиатрическая фармакология. 5;3: 46—54.

6. Sutherland LR, Martin F, Greer S et al. 1987. 5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctiti. Gastroenterology. 92(6): 1894—1898.

7. Chen GG, Lo SK. 2006. The challenge of using capsule endoscopy in the diagnosis and management of inflammatory bowel disease. Challenges in inflammatory bowel disease. Jewell DR, Mortennsen NJ, Steinhart AH et al. (eds). 2nd ed. Blackwell Publishing: 85—104.

8. Civitelli F, Di Nardo G, Oliva S et al. 2013. Colonic ultrasonography in pediatric ulcerative colitis: comparative study with colonoscopy. UEG Journal. 1; Suppl 1: 530.

9. Lightiger S, Present DH, Kornbluth A et al. 1994. Cyclosporine in severe ulcerative colitis refractory to steroid therapy. N Engl J Med. 330: 1841—1845.

10. Brand S, Stepp H, Oshsenkuln T et al. 1999. Detection of colonic dysplasia by light-induced fluorescence endoscopy: a pilot study. Int J Colorectal Dis. 14: 63—68.

11. Fagerhol MK, Dale I, Anderson T. 1980. Release and Quantitation of a Leucocyte Derived Protein (L1). Scand J Haematol. 24; Issue 5: 390—398.

12. Alqahtan A, Sunjic I, Shahib S et al. 2013 Fecal calprotectin, disease activity, and decision making in pediatric IBD. JPGN. 57; Suppl 1: 65—66.

13. Turner D, Levine A, Escher JC et al. 2012. Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines. JPGN. 55;3: 340—361.

14. Arienti V, Compieri M, Boriana L et al. 1996. Management of severe ulcerative colitis with the help of high resolution ultra sonography. Am J Gasroenterol. 91: 2163—2169.

15. Powel-Tuck J, Bown RL, Lennard-Jones JE. 1978. A comparison of oral prednisolon A comparison of oral prednisolone given as single or multiple daily doses for active proctocolitis. Scand J Gastroenterol. 13(7): 833—837.

16. Henderson P, Lawrence SJ, Casey A et al. 2013. The diagnostic accuracy of combining faecal calprotectin with common blood tests in the investigation of suspected paediatric inflammatory bowel disease. UEG Journal. 1; Suppl 1: 531.

17. Saliakellis E, Fotisl L, Sider S et al. 2013. The diagnostic value in paediatric small bowel assessment by wireless capsule endoscopy: a tertiary centre experience. UEG Journal. 1; Suppl 1: 491.

18. Truelove SC, Witts LJ. 1955. Cortisone in ulcerative colitis: final report on therapeutic trial. Br Med J. 2: 1041—1048.

19. Wilks S, Moxon W. 1875. Lectures on pathological anatomy. 22nd end Lindsay and Blakiston, Philadelphia: 408–409.