• Hypercoagulable states 
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Hypercoagulable states 

PERINATOLOGIYA I PEDIATRIYA. 2016.2(66):25-27; doi 10.15574/PP.2016.66.25 

Hypercoagulable states 

Ishchenko A. I., Demenina N. K., Milevskiy A. V.

SI «Institute of Pediatrics, Obstetrics and Gynecology NAMS Ukraine», Kiev 

Pregnancy causes a number of physiological changes, which affect the hematologic parameters, either directly or indirectly. The main reason for the increased risk of thromboembolism during pregnancy is hypercoagulability, which is likely to occur in order to protect a woman from bleeding due to miscarriage and childbirth. Woman's risk of thromboembolism during pregnancy and the postpartum period is increased by 4–5 times. Eighty percent of thromboembolic complications during pregnancy are venous, with a frequency of 0.49 to 1.72 per 1000 pregnancies. Risk factors include a history of thrombosis, hereditary and acquired thrombophilia, maternal age over 35, some medical conditions, as well as various complications of pregnancy and childbirth. Determining the cause hypercoagulability may help in choosing the duration and treatment of thrombosis. In the literature, there is no sufficient data of tests involving the use of anticoagulants during pregnancy. The purpose of this scientific review is a logical definition and assistance in choosing the treatment tactics hypercoagulable syndrome. 

Key words: hypercoagulable states, thrombophilia, pregnancy, haemostasis, antiphospholipid syndrome, bleeding. 


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