• Gorham—Stout disease of the thoracic and lumbar spine, ribs and with bilateral hydrothorax in a 11-year-old boy. Сlinical case

Gorham—Stout disease of the thoracic and lumbar spine, ribs and with bilateral hydrothorax in a 11-year-old boy. Сlinical case

SOVREMENNAYA PEDIATRIYA.2018.7(95):51-58; doi 10.15574/SP.2018.95.51

Dorosh O. I., Dudash P. J., Petronchak O. A., Masynnyk Yu. S., Seleznyov A. A., Shchurovskyj A. M., Kyrychuk I. V., Melko I. P.
Сommunal noncommercial enterprise of Lviv regional council «Western Ukrainian Specialized Children's Medical Centre», Ukraine
Communal institution of the Lviv Regional Council «Lviv Regional Pathological Anatomy Bureau», Ukraine
Center for Medical Innovations «NOVO», Lviv, Ukraine
Communal 4th City Clinical Hospital, Lviv, Ukraine
Pathomorphological Laboratory «CSD Health Care», Kyiv, Ukraine

Gorham—Stout disease (GSD) is a rare disease of uncertain etiology characterized by spontaneous and progressive idiopathic massive osteolysis of one or more skeletal bones without correlation with sex, race, type of inheritance, and place of geographical birth of patients. The international literature describes about 200 cases of the disease. Radiological and changes in GSD are specific, in some cases, full resorption of the affected bone with signs is possible. phantom bone or bone loss. The purpose of our report is to familiarize the medical community with this rare disease and to discuss the histological and clinical presentation of Gorem's disease with lesions of the thoracic and lumbar spine, ribs with bilateral hydrothorax, features of radiological findings with a brief overview of literature.

Key words: Gorham—Stout disease, osteolysitis, hemangiomatosis, bone disease, children, rare diseases.


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Article received: May 12, 2018. Accepted for publication: Nov 15, 2018.