• Gastrointestinal hyperactivity and its importance in the formationof chronic allergic gastritis in children 

Gastrointestinal hyperactivity and its importance in the formationof chronic allergic gastritis in children 

SOVREMENNAYA PEDIATRIYA.2016.1(73):127-130; doi10.15574/SP.2016.73.127 

Gastrointestinal hyperactivity and its importance in the formationof chronic allergic gastritis in children 

Bobrova V. I., Bogdanova T. A.

A.A. Bogomolets National medical university, Kiev, Ukraine 

Objective. To determine the clinical and pathogenetic role in the formation of gastrointestinal hyperactivity and chronic allergic gastritis in children. 

Patients and methods. We observed 82 children aged 6 to 16 years. To verify the diagnosis all the children performed endoscopy of the upper gastrointestinal tract, intragastric pHmeter. To confirm the genesis of atopic disease of patients determined the level general IgE in the serum by ELISA. 

Results. As a result of studies we find, that in majority (92.7±2.9%) patients examined early symptoms of gastrointestinal hyperactivity were diagnosed in the first six months of life. Gastrointestinal hyperactivity in infants is manifested by increased functional reaction of the gastrointestinal system, namely the disorders of the digestive and motorevacuation function of the gastrointestinal tract and symptoms of atopic dermatitis. In older children gastrointestinal hyperactivity transformed intoallergic gastritis, which is manifested by destructive changes of the gastric mucosa, increased production of hydrochloric acid , motility disorders of the gastrointestinal tract mainly in the form of duodenogastric reflux. It was found that the determining factors of the formation of allergic inflammation should be considered a high percentage of family history as a gastroenterological and allergic diseases, disorders physiological feeding graphics and nutrition of children from the first days of life. A characteristic feature of current gastroenterological diseases in patients with gastrointestinal hyperactivity was the absence of seasonal exacerbations, severe pain in the right upper quadrant, belching and flatulence, against the background of destructive changes in the gastric mucosa. 

Conclusions. We have identified specific clinical symptoms is pathognomonic for children with gastrointestinal hyperactivity and provides the opportunity to be watchful for the diagnosis of allergic changes in the gastric mucosa at the stage of clinical examination of the child. Installed us peculiarities formation of gastrointestinal hyperactivity will provide an opportunity to develop a differentiated approach to the treatment of chronic allergic gastritis. 

Key words: children, gastrointestinal hyperactivity, chronic allergic gastritis, diagnostics. 

REFERENCES

1. Botkina AS. 2012. Food allergies of children: modern approach to the problem. Lechaschiy vrach. 6: 24-26.

2. Zhernosek VF, Dyubkova TP. 2007ю Food allergy of infants. Minsk: 48.

3. Kaznacheeva LF. 2010. Gastrointestinal form of food allergy of children. Prakticheskaya meditsina. 45: 88—92.

4. Macharadze DSh. 2013. Atopic dermatitis and food allergies. What is common? Lechaschiy vrach. 5: 24—30.

5. Odarchenko IV, Svechnikova NN. 2001. Morphological changes of the mucous membrane of the stomach and colon of patients with different severity of atopic dermatitis. VIII Russian Congress of dermatovenerology. Abstracts of scientific papers. Part I. Dermatology. Moscow: 221—222.

6. Umanets TR, Shadrin OG, Klymenko VA, Nyankovskyy SL, Ashcheulov OM, Nyankovskа OS. 2015. The main provisions of the guideline for the management of patients with the cow's milk allergy. Part 1. Epidemiology and cow's milk allergens. Sovremennaya pediatriya. 1(65): 16—22. doi 10.15574/SP.2015.65.16

7. Ohotnikova EN, Chernyish YR. 2015. Gastrointestinal allergy in practice of Pediatrics and Pediatric Allergist. Zdorovie rebyonka. 4: 15—21.

8. Balabolkina II, Revyakinoy VA. 2010. Food allergies of children. Edited by II Balabolkina, VA Revyakinoy. Moscow: 190.

9. Hоst A, Andrae S, Charkin S et al. 2003. Allergy testing in children: why, who, when and how? Allergy. 58: 559—569.

10. Fiocchi A, Bouygue GR, Martelli A et al. 2004. Dietary treatment of childhood atopic eczema/dermatitis syndrome (AEDS). Allergy. 59; Suppl 78: 78—85.

11. Eichenfild LF. 2004. Consensus guidelines in diagnosis and treatment of atopic dermatitis. Allergy. 59; Suppl 78: 86—92.

12. Levy Y, Danon Y. 2003. Food protein-induced enterocolitis syndrome — not only due to cow's milk and soy. Pediatr Allergy Immunol. 14: 325—329.

13. Strobel S, Hourihane J. 2001. Gastrointestinal allergy: clinical symptoms and immunological mechanisms. Pediatr Allergy Immunol. 12; Suppl 14: 43—46.

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