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Gastrointestinal hyperactivity and its importance in the formationof chronic allergic gastritis in children 

SOVREMENNAYA PEDIATRIYA.2016.1(73):127-130; doi10.15574/SP.2016.73.127 

Gastrointestinal hyperactivity and its importance in the formationof chronic allergic gastritis in children 

Bobrova V. I., Bogdanova T. A.

A.A. Bogomolets National medical university, Kiev, Ukraine 

Objective. To determine the clinical and pathogenetic role in the formation of gastrointestinal hyperactivity and chronic allergic gastritis in children. 

Patients and methods. We observed 82 children aged 6 to 16 years. To verify the diagnosis all the children performed endoscopy of the upper gastrointestinal tract, intragastric pHmeter. To confirm the genesis of atopic disease of patients determined the level general IgE in the serum by ELISA. 

Results. As a result of studies we find, that in majority (92.7±2.9%) patients examined early symptoms of gastrointestinal hyperactivity were diagnosed in the first six months of life. Gastrointestinal hyperactivity in infants is manifested by increased functional reaction of the gastrointestinal system, namely the disorders of the digestive and motorevacuation function of the gastrointestinal tract and symptoms of atopic dermatitis. In older children gastrointestinal hyperactivity transformed intoallergic gastritis, which is manifested by destructive changes of the gastric mucosa, increased production of hydrochloric acid , motility disorders of the gastrointestinal tract mainly in the form of duodenogastric reflux. It was found that the determining factors of the formation of allergic inflammation should be considered a high percentage of family history as a gastroenterological and allergic diseases, disorders physiological feeding graphics and nutrition of children from the first days of life. A characteristic feature of current gastroenterological diseases in patients with gastrointestinal hyperactivity was the absence of seasonal exacerbations, severe pain in the right upper quadrant, belching and flatulence, against the background of destructive changes in the gastric mucosa. 

Conclusions. We have identified specific clinical symptoms is pathognomonic for children with gastrointestinal hyperactivity and provides the opportunity to be watchful for the diagnosis of allergic changes in the gastric mucosa at the stage of clinical examination of the child. Installed us peculiarities formation of gastrointestinal hyperactivity will provide an opportunity to develop a differentiated approach to the treatment of chronic allergic gastritis. 

Key words: children, gastrointestinal hyperactivity, chronic allergic gastritis, diagnostics. 


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