• Extra-oesophageal manifestations of gastroesophageal reflux disease in frequently ill children

Extra-oesophageal manifestations of gastroesophageal reflux disease in frequently ill children

SOVREMENNAYA PEDIATRIYA.2018.3(91):65-69; doi 10.15574/SP.2018.91.65

Pochinok T. V., Zhuravel O. V., Voronina S. S., Gurieva O. V.
Bogomolets National Medical University, Kyiv, Ukraine

The article analyses the literature data on clinical conditions that can be non-oesophageal manifestations of gastroesophageal reflux disease (GERD) in frequently ill children (FIC). It was established that extra-oesophageal manifestations of GERD in FIC should be taken into account during primary diagnosis and during the whole follow-up care. The most frequent associations are reflux-induced cough syndrome, reflux-laryngitis syndrome, reflux-asthma syndrome, and dental reflux-erosion syndrome. Among the non-oesophageal variants of GERD in FIC there is a special otorhinolaryngological form, which is contributed to the development of chronic laryngitis in 80.0% of cases, chronic pharyngitis — in 60.0% and their combination — in 48.0% of cases. Reflux-induced lesions include changes in the nasal cavity and auditory tube in the form of chronic sinusitis, sinusitis and recurrent otitis media. The severe extra-oesophageal manifestations of GERD in FIC, according to the literature data, is tracheal stenosis, reflux-induced bronchial asthma, and idiopathic pulmonary fibrosis; as an additional examination, it is recommended to perform contrast fluoroscopy of the oesophagus and stomach, pH monitoring, spirometry with bronchial provocation tests, fibrogastroduodenoscopy with targeted biopsy.

Key words: gastroesophageal reflux disease, extra-oesophageal manifestations, frequently ill children.


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