• Evaluation of the cardiovascular system status in children with rheumatic diseases by means of the hardware-software complex «Cardio-plus P»

Evaluation of the cardiovascular system status in children with rheumatic diseases by means of the hardware-software complex «Cardio-plus P»

SOVREMENNAYA PEDIATRIYA.2017.8(88):59-67; doi 10.15574/SP.2017.88.59

Oshlianska O. A., Chaikovskyi  I. A., Artsymovych A. H., Dordiienko M. O.
Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine
SI «Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine», Kyiv, Ukraine
Glushkov Institute of Cybernetics of National Academy of Sciences of Ukraine, Kуiv, Ukraine
G.V. Kurdyumov Institute for Metal Physics of the N.A.S. of Ukraine, Kуiv, Ukraine

Objective: to investigate the effectiveness of the 4th generation electrocardiography in the early diagnosis of cardiovascular changes in children with rheumatic diseases.
Material and methods. In total 27 hospitalized patients with rheumatic diseases were examined. Clinical and laboratory tests were conducted; ECG was registered by means of the hardware-software complex «Cardio-plus P» as well as a traditional 12-channel ECG.
Results and discussion. According to the standard 12-channel ECG, only 4 patients had no changes. However, the revealed changes were minimal, generally of a functional nature and not diagnostically significant for the detection of a certain cardiac pathology. Summarizing the results of the analysis of neuron-endocrine regulation of heart function, the functional status of the myocardium, the evaluation of rhythm disturbances and the psychoemotional state according to ECG data registered by HSC «Cardio-plus P», it was possible to note the presence of hidden disorders in all those areas of CVS. In general, the complex index of the functional status of the cardiovascular system in patients with rheumatic diseases was also reduced — 60.17391±1.91, and it was more than 70% only in 4 patients (14.8%).
Conclusion. The damages of CVS in children with rheumatic diseases develop not only due to autoimmune disorganization of the myocardium, but also as a result of metabolic disorders. For the most part, they are non-indicative, have a subclinical nature and are not recorded using standard research methods. Using the HSC «Cardio-plus P» allows to increase by threefold of the CAS changes detection in children with rheumatic diseases by evaluating complex indicators, reveal hidden cardiac rhythm disturbances.
Key words: electrocardiography, rheumatic diseases, children.


1. Oshlyanskaya OA, Myasnikov GV, Kazmirchuk AP et al. (2014, Dec). Some ways to improve the methods of diagnosing heart lesions in children with rheumatic diseases. Sertseva nedostatnistʹ. 3: 12-21.

2. Kovalenko VN, Chaikovsky IA, Faizilberg LS et al. (2007). The diagnostic value of electrocardiography in the phase space for the screening of ischemic heart disease. Ukr kardiol zhurnal. 6: 13-19.

3. Omelchenko LI, Oshlyanskaya OA, Tchaikovsky IA, Faizilberg LS. (2010). New approaches to heart screening in children with connective tissue pathology. Sovremennaya pediatriya. 4(32): 117-121.

4. Omelchenko LI, Nikolaenko VB, Dudka IV. (2010). Prevention of side effects of glucocorticoid therapy in children with rheumatic diseases. Guidelines. Kyiv: 28.

5. Tchaikovsky IA. (2013). Electrocardiogram analysis in one, six and twelve leads in terms of information value: electrocardiographic cascade. Klyn іnform і telemed. 9(10): 20-31.

6. Robillon JF, Sadoul JL, Jullien D et al. (2004, May 11). Abnormalities suggestive of cardiomyopathy in patients with T2DM. 109(18): 2191–2196.

7. Comorbidity in Rheumatic Diseases Yasser El. (2017). Miedany Springer: 433.

8. Maradit-Kremers H, Crowson CS, Nicola PJ et al. (2005, Feb). Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study. Arthritis Rheum. 52(2): 402-11. https://doi.org/10.1002/art.20853; PMid:15693010

9. Cecchi F, Montereggi A, Olivotto I et al. (1997). Risk for atrial fibrillation in patients with hypertrophic cardiomyopathy assessed by signal-averaged P-wave. Circulation. 59: 866-875. https://doi.org/10.1136/hrt.78.1.44

10. Leuven ST, Franssen R, Kastelein JJ et al. (2008). Systemic inflammation as a risk factor for atherothrombosis. Rheumatology. 47: 3-7. https://doi.org/10.1093/rheumatology/kem202; PMid:17702769

11. Yan G, Martin J. (2003). Electrocardiographic T-wave: a symbol of Transmural dispersion of repolarisation in the ventricles. JCardiovasc Electrophysiol. 14: 639-640. https://doi.org/10.1046/j.1540-8167.2003.03155.x; PMid:12875426