• Epstein—Barr viral infection in children 
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Epstein—Barr viral infection in children 

SOVREMENNAYA PEDIATRIYA.2015.4(68):103-110; doi 10.15574/SP.2015.68.103 

Epstein—Barr viral infection in children 

Volokha A. P.

Shupyk National Medical Academy of Postgraduate Education 

Epstein—Barr virus (EBV) — extremely common virus in a population, the causative agent of infectious mononucleosis, symptoms persist lifelong in infected individuals. Unlike other herpesviruses reactivation of EBV does not have significant value in clinical practice, except immunocompromised patients (X-linked lymphoproliferative syndrome, immunosuppression after transplantation), who develops lymphoproliferative disorders. Epstein—Barr virus is associated with the development of malignancy. Primary EBV infection is usually asymptomatic in young children, at an older age it occurs with classical symptoms: fever, sore throat, lymphadenopathy. Recovery complete within a few weeks of onset. The mainstay of treatment EBV-induced infectious mononucleosis is symptomatic therapy. The issue of appointment of antiviral drugs and corticosteroids in the treatment of primary EBV-infection is debatаble and not recommended in general. 

Key words: Epstein—Barr virus, infectious mononucleosis, children. 


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