• Efficacy of hepatoprotective therapy with the complex drug «Betargin» in children with non-alcoholic fatty liver disease

Efficacy of hepatoprotective therapy with the complex drug «Betargin» in children with non-alcoholic fatty liver disease

SOVREMENNAYA PEDIATRIYA.2018.3(91):102-111; doi 10.15574/SP.2018.91.102

Abaturov A. E., Kryuchko Т. A., Krivusha E. L., Poda O. A.
SI «Dnіpropetrovsk Medical Academy of Health Ministry of Ukraine», Dnipro, Ukraine
HSEI «Ukrainian Medical Stomatological Academy», Poltava, Ukraine

An article covers the problem on preventing the development of non-alcoholic fatty liver disease (NAFLD) in children with the alimentary-constitutional type of obesity.

Objective: to study the efficacy and safety of the betaine-arginine complex «Betargin» using for normalizing the basic metabolic processes of carbohydrate and fat metabolism in children with obesity in order to prevent the development and progression of steatohepatosis. In total 70 overweight children were followed-up. A full range of clinical, laboratory and instrumental research, which allow diagnosing NAFLD at early stages of its development, were carried out. Overweight children were administered the complex drug «Betargin» with the aim of preventing the development of NAFLD. The efficacy of the drug has been set on the basis of clinical, laboratory and instrumental examinations conducted after the therapy.

Key words: children, obesity, non-alcoholic fatty liver disease, betaine, arginine, hepatoprotective effect, treatment.

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