- Efficacy of diagnosis and treatment of pneumonia in pregnant women according to the modern European and national recommendations
Efficacy of diagnosis and treatment of pneumonia in pregnant women according to the modern European and national recommendations
PERINATOLOGY AND PEDIATRIC. UKRAINE. 2018.1(73):48-52; doi 10.15574/PP.2018.73.48
Lymanska A. Yu., Ohorodnyk A. O., Davydova Yu. V.
SI «Institute of Pediatrics, Obstetrics and Gynaecology of NAMS of Ukraine», Kyiv, Ukraine
Objective — to determine the efficacy of the drug Azaks (Nobel) in the treatment of pneumonia in pregnant women against extragenital pathology.
Material and methods. Eight pregnant women with community acquired pneumonia were under observation, out of those 4 patients with mild pneumonia and 4 with moderate course of disease. Five (41.6%) women had congenital heart defects, 3 (25%) hypertensive disease I grade, and 4 (33.3) women had heart defects of rheumatic origin. In all cases, pneumonia was associated with pre-existing acute viral infection. The pregnant women with mild pneumonia were administered Azax as monotherapy at a dose 500 mg once a day during 5 days, and the pregnant women with moderate pneumonia were administered comprehensive treatment (amoxicillin with clavulanic acid intravenously and azithromycin (Azax) orally) during 10 days.
Results. It was found high efficacy of antibiotic therapy with the use of azithromycin based on the treatment results in pregnant women. Examination the foetal status using ultrasound and Doppler echography revealed no negative effect of antibiotic therapy on maternal and foetal blood flow, as well as no signs of foetal growth retardation.
Conclusions. Treatment of pneumonia in pregnant women should comply with the standard treatment principles of adults. The high safety profile of azithromycin (Azax, Nobel) makes it possible to use it as an antibiotic therapy for pneumonia in pregnants of high-risk groups.
Key words: pregnancy, community acquired pneumonia, antibiotic therapy, azithromycin.
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