• Effects of the iodine supplementation on physical and psychomotor development in young children and their neurological status
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Effects of the iodine supplementation on physical and psychomotor development in young children and their neurological status

SOVREMENNAYA PEDIATRIYA.2017.1(81):13-19; doi 10.15574/SP.2017.81.13

Mamenko M. Ye., Shleyenkova G. O., Doncova K. M.
Shupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine
Kharkov Medical Academy of Postgraduate Education, Ukraine
Luhansk regional orphanage № 2, Severodonetsk, Ukraine

Introduction. Iodine deficiency has adverse effects at the metabolism and energy, somatic growth and the formation of structures of nervous system.

The aim. To evaluate the effects of the iodine supplementation on the functional activity of the pituitary-thyroid system, mental development and neurological status of young children.

Materials and methods. 123 children from orphanage aged from 2 to 3.5 months participated in the survey. Physical and neuropsychological development was assessed in all children. Neurological examination and determination of TSH, T4, T3 was performed.

Results. All children had burdened prenatal history (100%), decreased physical development (44.9%), deficiency in psychomotor development (95.7%), decreased coefficient of neuropsychological development (82 points), neurological disorders (94.1%). The most common was the syndrome of static, kinetic, mental and pre-speech retardation (49.2%, p χ2<0,001). Iodine deficiency was insufficient (median of daily iodine excretion of the urine was 56.5 mg). Iodine supplementation (50 mg per day for 6 months) reduced the TSH level from 3.21 mU/L to 1.96 mU/l (pu=0,000). It results in normalization of physical and neuropsychological development.

Conclusions. Iodine supplementation is an effective mean of correcting physical, neuropsychological development and improvement of neurological status in children with dysfunction of the nervous system.

Key words: iodine, pituitary-thyroid system; neurologic status; psychological development young children.


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