• Effectiveness of controlled ovulation stimulation in women with low ovarian reserve

Effectiveness of controlled ovulation stimulation in women with low ovarian reserve

HEALTH OF WOMAN. 2018.5(131):45–47; doi 10.15574/HW.2018.131.45

Prodan T. A., Dankovich N. O., Babenko O. M.
Medical Center «Mother and Child», Kyiv

The objective: of the investigation was to study the effectiveness of controlled ovulation stimulation (СOS) in women with low ovarian reserve of various etiologies.

Materials and methods. To achieve this goal, a prospective analysis of the results of COS in 60 patients with a reduced ovarian reserve was carried out. All patients were divided into 2 groups: the first group included patients with ovarian reserve reduction due to the presence of surgical interventions on the ovaries (n=30), the second group – without operation on reproductive organs in the past (n=30). Within the framework of the study, the duration of stimulation, the number of follicles and oocytes obtained were estimated.

Results. The number of follicles obtained was significantly (almost 2 times) higher in patients of the 1-st group (p<0.05). Namely: in women with operated ovaries it were an average 8–9 follicles and 2–3 oocytes was obtained, whereas in patients with low ovarian reserve without surgery – only 4–5 follicles and 1–2 oocytes.

Conclusions. A prospective study showed that in women with a reduced ovarian reserve the effectiveness of COS depends primarily on the etiologic factor of reducing the number of antral follicles.

Key words: ovarian reserve, operated ovaries, controlled ovulation stimulation.

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