• Effect of cultured milk products on the microbiocenosis and local immunity of the intestine in infants: results of study 
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Effect of cultured milk products on the microbiocenosis and local immunity of the intestine in infants: results of study 

SOVREMENNAYA PEDIATRIYA.2014.1(57):113-121; doi 10.15574/SP.2014.57.113 

Effect of cultured milk products on the microbiocenosis and local immunity of the intestine in infants: results of study 

Rodionov V. P., Matvienko I. M., Kvashnina L. V., Kravchenko O. M.

SU «Institute of Pediatrics, Obstetrics and Gynecology» NAMS of Ukraine, Kiev 

Objective. To study the effect of children's products «Syrok detskiy «Agusha» and «Yogurt detskiy «Agusha» on formation and maintenance of the intestinal microflora and its protective capacity, balance of protein and calcium metabolism; to determine the safety, tolerability and efficacy of these products in the diet of infants. 

Patients and methods. The study involved 80 clinically healthy children in the age from 6 to 36 months who had received cultured milk products «Agusha» in the dosage according to the age during 45 days. All children had passed examination of intestinal microflora at the beginning and for the end of the study with the use of standard methods and also examination of the local intestinal immune system state. 

Results. According to the bacteriological examination of defecations conducted at the beginning of the examination disbiotic changes as in anaerobic so in aerobic links of intestine microbiocenosis were found in all children. In the setting of application of cultured milk products «Agusha» was marked increasing of the number of intestinal normal flora, reducing of opportunistic pathogenic and pathogenic microflora due to antagonistic effect of lactic acid bacteria; the normalization of condition of the local intestinal immunity. The use of «Agusha» products allowed closing children's diet to normative age indicators by major nutrients. 

Conclusions. Positive impact of products «Agusha» on intestine microbiocenosis and local immunity, high nutritional value and good tolerability allow recommending their use for the prevention of intestinal microbiocenosis disorders and also for complex treatment of dysbiosis in children without additional application of pre- and probiotics. 

Key words: infants, intestinal microbiocenosis, local immunity, cultured milk products. 

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