• Development of the immune response in pneumonia caused by Klebsiella pneumoniae. Part 1

Development of the immune response in pneumonia caused by Klebsiella pneumoniae. Part 1

SOVREMENNAYA PEDIATRIYA.2017.5(85):94-109; doi 10.15574/SP.2017.85.94

Abaturov A. E., Nikulina A. A.
SE «Dnepropetrovsk Medical Academy of Health Ministry of Ukraine», Dnepr, Ukraine

The article shows the role of Klebsiella pneumoniae in the structure of nosocomial pneumonia and the immune response mechanisms aimed at eradication of the extracellular pathogen. Based on the analysis of literature sources, the current understanding of the molecular mechanisms of recognition of the Klebsiella pneumoniae pathogen-associated molecular patterns and the induction of intracellular signaling pathways of effectory cells of the respiratory tract is presented.
Key words: pneumonia, Klebsiella pneumoniae, children, immune response, PRR.

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