• Current insights on the role of umbilical cord disease in perinatal medicine (Сlinical lecture)

Current insights on the role of umbilical cord disease in perinatal medicine (Сlinical lecture)

HEALTH OF WOMAN. 2018.10(136):10–14; doi 10.15574/HW.2018.136.10

Nazarenko L. G.
Kharkiv medical Academy of postgraduate education

The urgency of the problem of abnormalities in the structure and location of the umbilical cord is determined by their widespreadness, interconnectedness with the development of intranatal distress, asphyxia and stillbirth. This pathology is characterized by imperfection of diagnostics, unpredictability of consequences, underestimation of clinical significance for neuropsychological development of the child in subsequent periods of life. The article presents data on individual variants of the pathology of the umbilical cord, showing their origin and clinical significance. The expediency of targeted attention to antenatal diagnosis of abnormalities of construction, function and location of the umbilical cord to prevent intranatal mortality and complications of the newborn is emphasized.

Key words: umbilical cord, anomalies, perinatal pathology, inflammation, bending.

REFERENCES

1. Aryaеv VK. (2003). Neonatologіya. K, ADEF-Ukraіna:110–139.

2. Shabalov NP, Lyubimenko NP, Lyubimenko VA i dr. (1999). Asfiksiya novorozhdennyih. M, MEDpress:346.

3. Brehman GI. (2006). Volnovyie mehanizmyi obmena informatsiey v obnovlyaemyih sistemah. Sistemnyie issledovaniya i upravlenie otkryityimi sistemami. Hayfa. 2:87–96.

4. Altherr P, Berg L, Velfl A, Passolt M. (2004). Giperaktivnyie deti. Korrektsiya psihomotornogo razvitiya. M, Akademiya:160.

5. Ma’ayeh M, Varughese A, Purandare N et al. (2014, Jan). Hypercoiling of the umbilical cordeis it clinically relevant? American Journal of Obstetrics & Gynecology 210;1:107.

6. Evtushenko SK, Poroshina EV, Omelyanenko AA. (2010). Sindrom defitsita vnimaniya i giperaktivnosti u detey s izmenennoy i neizmenennoy EEG: novyie podhodyi v terapii. Mezhdunarodniy nevrologicheskiy zhurnal 5(35). Elektronnyiy resurs Rezhim dostupa: http://www.mif-ua.com/archive/issue-13643/

7. Chagaev ChG. (2011). Patologiya pupovinyi. Pod red. prof. VE Radzinskogo. M, GOETAR-Media:96.

8. Baergen RN. (2011). Manual of pathology of the human placenta. New York, Springer-Verlag: 540. https://doi.org/10.1007/978-1-4419-7494-5

9. Collins JH, Collins CL, Collins CC. (2004). Umbilical Cord Accidents: 72.

10. Costa SL. (2008). Screening for Placental Insufficiency in High-risk Pregnancies: Is Earlie Better? Placenta 29;12:1034–1040. https://doi.org/10.1016/j.placenta.2008.09.004; PMid:18930542

11. Gilbert JS et al. (2012). Circulating and utero-placental adaptation to chronic placental ischemia in rat. Placenta 33;2:100–105. https://doi.org/10.1016/j.placenta.2011.11.025; PMid:22185915

12. Machin GA, Ackerman J, Gilbert-Barness E. (2000). Abnormal umbilical cord coiling is associated with adverse perinatal outcomes. Pediatr. Dev Pathol. 3(5):462–471. https://doi.org/10.1007/s100240010103; PMid:10890931

13. Meng F, To W, Kirkman-Brown J et al. (2007). Calcium oscillations induced by ATP in human umbilical cord smooth muscle cells. Journal of Cellular Physiology 123;1:79–87. https://doi.org/10.1002/jcp.21092; PMid:17477379

14. Park Ch-W, Park JS, Mi S et al. (2017). Longer latency to delivery is associated with more frequent inflammation-free extra-placental membranes and umbilical cord in the setting of preterm-PROM with intra-amniotic inflammation. American Journal of Obstetrics & Gynecology 216;1:201–202. https://doi.org/10.1016/j.ajog.2016.11.590

15. Pathak S, Hook E, Hackett G. (2010). Cord coiling, umbilical cord insertion and placental shape in an unselected cohort delivering at term: relationship with common obstetric outcomes. Placenta 31;11:963–968. https://doi.org/10.1016/j.placenta.2010.08.004; PMid:20832856

16. Proctor LK. (2013). Umbilical cord diameter percentile curves and their correlation to birth weight and placental pathology. Placenta 34:62–66. https://doi.org/10.1016/j.placenta.2012.10.015; PMid:23174148

17. Rosenbloom JI, Molly J, Stout MJ et al. (2017, Jan). Electronic fetal monitoring patterns on admission and in the active phase associated with elevated umbilical cord arterial lactate at term. American Journal of Obstetrics & Gynecology 216;1,Supplement:S438–S439. DOI: https://doi.org/10.1016/j.ajog.2016.11.489. https://doi.org/10.1016/j.ajog.2016.11.489

18. Sebire NJ. (2007). Pathophysiological significance of abnormal umbilical cord coiling index. Ultrasound Obstet. Gynecol. 30(6):804–806. https://doi.org/10.1002/uog.5180; PMid:17960724

19. Timofeev J, Holland M, Clark-Ganheart C et al. (2014, Jan). Assessment of the number of umbilical cord vessels at the time of nuchal translucency screening. American Journal of Obstetrics & Gynecology 210;1, Suppl:S90. https://doi.org/10.1016/j.ajog.2013.10.188

20. Tuuli M, Shanks A, Odibo A et al. (2014). Umbilical cord arterial lactate compared with pH for predicting neonatal morbidity at term: a prospective cohort study. American Journal of Obstetrics & Gynecology 210;1:21–22. https://doi.org/10.1016/j.ajog.2013.10.065

21. Weiner E, Fainstein N, Bar J, Kovo M. (2015). The role of the umbilical cord in the genesis of non-reassuring fetal heart rate leading to emergent cesarean sections. American Journal of Obstetrics & Gynecology 212;1:134.