• Congenital malformations in children born using assisted reproductive technologies 
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Congenital malformations in children born using assisted reproductive technologies 

SOVREMENNAYA PEDIATRIYA.2016.8(80):45-48; doi 10.15574/SP.2016.80.45 

Congenital malformations in children born using assisted reproductive technologies 

Stoieva T. V., Synenko V. V., Strechen E. A.

Odessa National Medical University, Ukraine


Objective — to determine the frequency and structure of congenital malformations in children born as a result of induced pregnancy.


Patients and methods. To achieve the goal were examined 74 children who was born with the help of reproductive technology (ICSI technique).


Results. The frequency of malformations in examined children was 24.3%. The cardiovascular malformations, urinary and digestive systems, as well as the abnormal of musculoskeletal system and sensory organs are defined in this structure. The proportion of big defects was 27.8%, small anomalies of development — 72.2%. Analysis of the anamnestic factors importance of demonstrated the presence of association of malformations occurrence and somatic (χ2=8.4, p=0.004) and reproductive (χ2=14.45, p=0.0001), health mothers of children examined.


Conclusions. The analysis showed a high incidence of congenital malformations in children born as a result of induced pregnancy. In the structure of registered prevalence of small anomalies (p<0.001) on the appearance of which is significantly affected by health of mothers.


Key words: children, ART (ICSI), congenital malformations.


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