• Clinical experience with Septolete plus products in the treatment of sore throat 
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Clinical experience with Septolete plus products in the treatment of sore throat 

SOVREMENNAYA PEDIATRIYA.2015.7(71):26-31 
 

Clinical experience with Septolete plus products in the treatment of sore throat 
 

Kosir Р. 
 

A sore throat is a common complaint among children, adolescents and adults. It refers to a painful sensation localised to the pharynx and surrounding anatomy and can be a symptom of a disease process not directly linked to the pharynx (e.g. cold or flu). The treatment of sore throat depends upon the cause. Due to the predominantly viral cause, antibiotics have only a marginal benefit as they do not improve throat pain and are thus not recommended. An alternative to systemic antibiotic therapy in such cases is the use of oral antiseptics, which are often combined with local anesthetics to relieve pain and thus alleviate subjective discomfort. Septolete plus products contain a broad-spectrum antiseptic, cetylpyridinium chloride (CPC), and the local anesthetic benzocaine. In clinical studies Septolete plus has demonstrated high efficacy and good tolerability in the treatment of sore throat. The analgesic effect of Septolete plus lozenges started in fifteen minutes and lasted for two to three hours. Complete healing or improvement of the signs and symptoms of the disease was observed in 90–100% of the patients treated with Septolete plus lozenges and 87.5% of the patients treated with Septolete plus oromucosal spray. Secondary infections occurred in not more than 3.8% of the patients treated with lozenges. Additionally, a considerable reduction in the microorganism count was demonstrated for Septolete plus lozenges. 
 

Key words: pharyngitis, antiseptics, local anesthetics, cetylpyridinium chloride, benzocaine. 
 

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