• Ballantyne syndrome: a review of of literature and a clinical case report
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Ballantyne syndrome: a review of of literature and a clinical case report

HEALTH OF WOMAN. 2019.5(141): 8–11; doi 10.15574/HW.2019.141.8

Lakhno I. V.
The review of literature and a case report of mirror syndrome were performed. The main role of the placental lesions in the pathogenetic scenario was shown. The high level of the perinatal pathology is a reason for the continual search in the field.
Key words: mirror syndrome, a system of «mother–placenta–fetus», perinatal pathology.


Allarakia S, Khayat HA, Karami MM, Aldakhil AM, Kashi AM, Algain AH, Khan MA, Alghifees LS, Alsulami RE. 2017, Dec 20. Characteristics and management of mirror syndrome: a systematic review (1956-2016). J Perinat Med. 45(9):1013-1021. https://doi.org/10.1515/jpm-2016-0422; PMid:28315852

Ballantyne JW. The disease and deformities of the fetus. Edinburgh: Oliver & Boyd; 1892.

Braun T, Brauer M, Fuchs I, Czernik C, Dudenhausen JW, Henrich W, Sarioglu N. 2010. Mirror syndrome: a systematic review of fetal associated conditions, maternal presentation and perinatal outcome. Fetal Diagn Ther. 27(4): 191–203. https://doi.org/10.1159/000305096; PMid:20357423

Chimenea A, García-Díaz L, Calderón AM, Heras MML, Antiñolo G. 2018. Resolution of maternal mirror syndrome after successful fetal intrauterine therapy: a case series. BMC Pregnancy Childbirth 18(1):85. https://doi.org/10.1186/s12884-018-1718-0; PMid:29625560 PMCid:PMC5889608

Espinoza J, Romero R, Nien JK, Kusanovic JP, Richani K, Gomez R. 2006. A role of the anti-angiogenic factors VEGFR-1 in the “mirror syndrome” (Ballantyne’s syndrome) J. Matern. Fetal Neonatal Med. 19: 607–613. https://doi.org/10.1080/14767050600922677; PMid:17118734

Hobson SR, Wallace EM, Chan YF, Edwards AG, Teoh MWT, Khaw AP. 2019. Mirroring preeclampsia: the molecular basis of Ballantyne syndrome. J Matern Fetal Neonatal Med. 6:1-6. https://doi.org/10.1080/14767058.2018.1500550; PMid:30614331

Lakhno I, Behar JA, Oster J, Shulgin V, Ostras O, Andreotti F. 2017. The use of non-invasive fetal electrocardiography in diagnosing second-degree fetal atrioventricular block. Matern Health Neonatol Perinatol. 3: 14. https://doi.org/10.1186/s40748-017-0053-1; PMid:28794892 PMCid:PMC5541729

Mathias CR, Rizvi C. 2019. The diagnostic conundrum of maternal mirror syndrome progressing to pre-eclampsia – A case report. Case Rep Womens Health 23:e00122. https://doi.org/10.1016/j.crwh.2019.e00122; PMid:31193796 PMCid:PMC6542765

Mangoub FE, Bouhou RA, Idri Z, Kouach J, Guelzim K, Rahali DM. 2018. Ballantyne syndrome complicated by eclampsia: about a case and literature review. Pan Afr Med J. 30: 238. https://doi.org/10.11604/pamj.2018.30.238.15296; PMid:30574257 PMCid:PMC6295295

Navarro-Perez Silvia F, Corona-Fernandez Karen. 2019. Significant clinical manifestations in Ballantyne syndrome, after a case report and literature review: recognizing preeclampsia as a differential diagnosis. Case Rep. Obstet. Gynecol. 2019:7. https://doi.org/10.1155/2019/2013506; PMid:30949371 PMCid:PMC6425318

Umazume T, Morikawa M, Yamada T, Minakami H. 2016. Changes in echocardiography and blood variables during and after development of Ballantyne syndrome. BMJ Case Rep. 2016:bcr2016216012. https://doi.org/10.1136/bcr-2016-216012; PMid:27329098 PMCid:PMC4932354