• Assisted reproductive technology and intrauterine pathology as the risk factors of placenta praevia 
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Assisted reproductive technology and intrauterine pathology as the risk factors of placenta praevia 

HEALTH OF WOMAN. 2016.10(116):140–142; doi 10.15574/HW.2016.116.136 

Assisted reproductive technology and intrauterine pathology as the risk factors of placenta praevia 

Makarenko M., Govsieiev D., Martynova L., Berestovoy V., Vorona R.

A.A. Bogomolets National Medical University, Kiev

Global data show that the probability of occurrence of placenta praevia is increased after treatment with the use of assisted reproductive technology (ART) from 2 to 6 times. However, until now it remains unknown what factors contribute to this increased risk.

The objective: perform a retrospective analysis of histories of the births which were complicated by placenta praevia. Determine the frequency of this pathology in the control group where the pregnancy was the result of self-fertilization and the group where the pregnancy was the result of ART.

Patients and methods. We have processed statistically the 20 919 birth histories from four Kyiv hospitals (№ 1, 2, 5 and 7) that took place in 2015. ART pregnancy occurred in 391 cases.

Results. The retrospective analysis of birth histories found 86 placenta praevia that was 0.38% of the total number of births. 8 cases of placenta praevia that was 2.04% were found among 391 ART pregnancies. Thus placenta praevia in ART group is 5 times greater than in control group of natural pregnancies. Intrauterine pathology was detected in 63% cases of ART pregnancies which was 2.5 times higher than the control group.

Conclusions. ART increases the number of pregnant women with placenta praevia in 5 times in comparison with natural pregnancies. Pregravid training with operative treatment in case of the intrauterine pathology reduces the number of pregnancies with the placenta praevia. The obtained data did not allow determining the final mechanism of occurrence of placenta praevia.

Key words: аssisted reproductive technology, intrauterine pathology, placenta praevia.


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