• Advantages of compression therapy in the conservative treatment of extensive complex hemangiomas in children

Advantages of compression therapy in the conservative treatment of extensive complex hemangiomas in children

PAEDIATRIC SURGERY.2016.3-4(52-53):38-41; doi 10.15574/PS.2016.52-53.38 
 

Advantages of compression therapy in the conservative treatment of extensive complex hemangiomas in children


Kovalenko A. N., Smirniy S. V., German V. N., Moroz V. I., Nedavniy G. V., Chekanov D. Yu., Ternavskiy M. S.

Bogomoletc National Medical University, Kiev, Ukraine

Сity hospital № 3, Mykolayiv, Ukraine

Mykolayiv regional Children’s Hospital, Ukraine


Objective: To analyze the main causes and consequences of extensive hemangiomas of upper and lower limbs in children, especially of the extensive complex forms, as well as current combination therapies.


Materials and Methods. We performed analysis of results of treatment of five patients with extensive mixed (complex and cavernous) hemangiomas that circularly occupied several limb segments with extension process on the forearm and hand, the localization of the shoulder, forearm, hand, and on the lower leg and foot.


Results. Since learning about this disease, for the entire period a technique of compression therapy, which consist in manufacturing and wearing of custom-made stretch stockinet, regular and basic care of the affected skin, were applied to five children. Gender distribution: 40% of boys and 60% girls. The patients’ age during compression therapy was 6.5±1.5 months. The period from start of treatment until the end amounted to 12-18 months, under the supervision of a dynamic observation.


Conclusions. Addressing the treatment of extensive hemangiomas of the limbs is an important issue in children with complex shape hemangiomas. Compression therapy appears to be a safe and effective modality for treating hemangiomas in children and allows for conservative treatment as an outpatient without surgical trauma of the child.


Keywords: child, complicated hemangioma, compression therapy.


References

1. Abshilava DI, Kolyigin BA, Gasanov DG. 1984. Vrachebnaya taktika pri gemangiomah u detey. L.

2. Gutkin DV, Lagunova ZV, Pancheshnikova ES et al. 2004. Gemangiomyi: etiologiya i patogenez. Eksperimentalnaya i klin dermatokosmetol. 2: 20-23.

3. Isakov YuF. Hirurgicheskie bolezni detskogo vozrasta. Uchebnik. V 2 t. Moskva, GEOTAR-Med: 632.

4. Puttgen KB, Summerer B, Schneider J et al. 2013. Cardiovascular and blood glucose parameters in infants during propranolol initiation for treatment of symptomatic infantile hemangiomas. Ann Otol Rhinol Laryngol. 122(9): 550-4. https://doi.org/10.1177/000348941312200903; PMid:24224397

5. Farhangi V, Sansone RA. 2003. QTc prolongation due to propranolol overdose. Int J Psychiatry Med. 33(2): 201-2. https://doi.org/10.2190/KLBE-UWHT-TARV-8E0M; PMid:12968835

6. Fette A. 2013. Propranolol in use for treatment of complex infant hemangiomas: literature review regarding current guidelines for preassessment and standards of care before initiation of therapy. Scientific World Journal. 2013: 850193. https://doi.org/10.1155/2013/850193. PMCID: PMC3673324

7. Janmohamed SR, Madern GC, de Laat PC, Oranje AP. 2011. Haemangioma of infancy: two case reports with an overdose of propranolol. Case Rep Dermatol. 3(1): 18–21. https://doi.org/10.1159/000324421; PMid:21931573 PMCid:PMC3175358

8. Hong E, Fischer G. 2012. Propranolol for recalcitrant ulcerated hemangioma of infancy. Ped Dermatol. 29: 64–67. https://doi.org/10.1111/j.1525-1470.2011.01547.x.

9. Tan CE, Itinteang T, Leadbitter P et al. 2014. Low-dose propranolol regimen for infantile haemangioma. J Paediatr Child Health. 51(4): 419-24. https://doi.org/10.1111/jpc.12720.

10. Marchuk DA. 2001. Pathogenesis of hemangioma. Clin Invest. 107(6): 665–666. https://doi.org/10.1172/JCI12470.

11. Leaute-Labreze C, Dumas de la Roque E, Hubiche T et al. 2008. Propranolol for severe hemangiomas of infancy. N Engl J Med. 358(24): 2649-51. https://doi.org/10.1056/NEJMc0708819.

12. Colella G, Vuolo G, Siniscalchi G, Itro A. 2005. Radiotherapy for maxillo-facial hemangiomas in children: dental and periodontal long term effects. Minerva Stomatol. 54(9): 509–516. PMid:16215535

13. Winter H, Drager E, Sterry W. 2000. Sclerotherapy for treatment of hemangiomas. Dermatol Surg. 26(2): 105-8. https://doi.org/10.1046/j.1524-4725.2000.98012.x; PMid:10691936

14. Zheng JW, Wang YA, Zhou GY et al. 2007. Head and neck hemangiomas: how and when to treat. Shanghai Kou Qiang Yi Xue. 16(4): 337—42. PMid:17924011