• The value of the interstitial cells of Cajal in the urinary bladder: current status of the issue

The value of the interstitial cells of Cajal in the urinary bladder: current status of the issue

SOVREMENNAYA PEDIATRIYA.2017.1(81):117-120; doi 10.15574/SP.2017.81.117

Shevchuk D. V.
Zhytomyr regional children's clinical hospital, Ukraine
Zhytomyr state University named after Ivan Franko, Ukraine
Shupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine

Interstitial cells of Cajal (ICC) were first discovered in 1893 in the wall of the intestine, and only after almost 100 years of interest in the ICC recovered. In addition, modern technologies have allowed to identify similar cells in other organs, in particular those that contain the muscle fibers and, accordingly, shall be subject to reduction. So, ICC was detected in the urinary tract, fallopian tubes, the seminiferous tubules etc. Further study of the functions of the ICC has established a link between human peripheral information of the bladder (neuromuscular dysfunction of bladder) and the concentration of ICC. Thus, the measurement of ICC in the bladder wall when it is dysfunction may affect the tactics of patient management in the future.

Key words: interstitial cells of Cajal, neuromuscular dysfunction of bladder.


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