• Transplantation of stem and progenitor cells in the long term for correction of the consequences of hypoxic-ischemic encephalopathy of newborn babies

Transplantation of stem and progenitor cells in the long term for correction of the consequences of hypoxic-ischemic encephalopathy of newborn babies

HEALTH OF WOMAN. 2016.10(116):110–120

Transplantation of stem and progenitor cells in the long term for correction of the consequences of hypoxic-ischemic encephalopathy of newborn babies

Veropotvelyan P. N., Tsehmistrenko I. S., Veropotvelyan N. P., Guzhevskaya I. V., Zhabitska L. A., Zhuravleva C. A. 
«Interregional centre of medical genetics and prenatal diagnosis», Krivoy Rog
Perinatal center, Kiev
National medical University named after O. O. Bogomolets, Kyiv

The review included the results of the mechanism of therapeutic action of stem cells in cerebral disorders in newborn babies. 
The results of the review of foreign publications to analyze different aspects of cell therapy, from the type of stem cells and sources. Studied the components that determine the positive effect in relation to the treatment of ischemia/hypoxia of the brain.
Shown high therapeutic efficiency of cellular technologies and the prospects of their application in neonatology. However, it is necessary to study this problem, aimed at a comprehensive characterization of cell type and dose, the optimal time and method of their conduct for the most effective application of cell therapy.

Key words: stem cells, newborn infants, hypoxic-ischemic encephalopathy, asphyxia.


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