• Spirometry peculiarities in children with different degrees of bronchial asthma controllability

Spirometry peculiarities in children with different degrees of bronchial asthma controllability

SOVREMENNAYA PEDIATRIYA.2017.2(82):97-101; doi 10.15574/SP.2017.82.97

Rechkina О. О., Rudenko S. M., Doroshenkova F. S., Kravtsova O. M.
State Institution «National institute of phthisiology and pulmonology named after F.G. Yanovskyi of NAMS of Ukraine», Kyiv

Objective. To study and estimate the respiratory function (RF) in children with bronchial asthma (BA) with different degrees of disease control.

Materials and methods. The estimation of RF in 111 children with different degrees of asthma control was performed. Children's age ranged from 5 to 17 years, mean age — 10.61±0.33 years.

Results. Prior to the test with bronchodilators, the obstructive type of respiratory impairment detected in 30 (27 %) cases of examined children. Reversibility of indicators was found in 63 (57 %) children during the test. An increase of the forced expiratory volume in one second (FEV1) in children with uncontrolled asthma (14.45±3.04 %) was significantly higher (p<0.05) compared with those in children with partial control (7.26 ± 1.09 %) and controlled course of the disease (6.4±2.05%). An increase of the maximal expiratory flow rate at 25 % of vital capacity (MFR25) was not significantly different in children with controlled (24.47 ± 5.54%), partially controlled (27.53 ± 4.11%) and uncontrolled (36.28 ± 6.61%) BA, which indicates a severe disorder at the level of small bronchi in children with controlled and partially controlled BA.

Conclusions. In children with BA a persisting change of RF of obstructive type, the abnormalities of lower respiratory tract, commonly of concealed nature, were observed. The «FEV1<80%» criterion of controllability has a low sensitivity in estimating the degree of BA control in children, while changes of MFR25 are more sensitive and manifest since before the changes of FEV1.

Key words. Spirometry, children, asthma, asthma control, MEF25.


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