• Micronutrient correction in pregnant women — modern state of the problem

Micronutrient correction in pregnant women — modern state of the problem

PERINATOLOGIYA I PEDIATRIYA.2017.1(69):87-90; doi 10.15574/PP.2017.69.87

Micronutrient correction in pregnant women — modern state of the problem

Limanskaya A., Davydova I. V., Butenko L. P.
SI «Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine», Kyiv

The review identifies current approaches to micronutrient correction in women during pregnancy: monotherapy and combined use of vitamins and micronutrients. The attention is focused on vitamins intake in pregnant women depending on gestational age and their role in development of fetus.

Key words: pregnancy, vitamins.


1. Bailey LB, Berry RJ. 2005. Folic acid supplementation and the occurrence of congenital heart defects, orofacial clefts, multiple births, and miscarriage. Am J Clin Nutr. 81; 5: 1213S—1217S. PMid:15883454

2. Czeizel AE. 1998. Periconceptional folic acid containing multivitamin supplementation. Eur J Obstet Gynecol Reprod Biol. 78; 2: 151—161. https://doi.org/10.1016/S0301-2115(98)00061-X

3. Krapels IP, van Rooij IA, Ocke MC et al. 2004. Maternal dietary B vitamin intake, other than folate, and the association with orofacial cleft in the off spring. Eur J Nutr. 43; 1: 7—14. https://doi.org/10.1007/s00394-004-0433-y; PMid:14991264

4. Zhang C, Qiu C, Hu FB et al. 2008. Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitus. PLoS One. 3; 11: e3753.

5. Milewicz T, Czyzewicz M, Stochmal E, Galicka-Latala D, Hubalewska-Dydejczyk A, Krzysiek J. 2011. Intake of iodine-containing multivitamin preparations by pregnant women from the Krakow region of Poland. Endokrynol Pol. 62; 4: 309—315. PMid:21879470

6. Patterson D. 2008. Folate metabolism and the risk of Down syndrome. Downs Syndr Res Pract. 12; 2: 93—97. https://doi.org/10.3104/updates.2051; PMid:19026278

7. Pittas AG, Sun Q, Manson JE et al. 2010. Plasma 25-hydroxyvitamin D concentration and risk of incident type 2 diabetes in women. Diabetes Care. 33; 9: 2021—2023. https://doi.org/10.2337/dc10-0790; PMid:20805275 PMCid:PMC2928356

8. Rumbold A, Middleton P, Crowther CA. 2005. Vitamin supplementation for preventing miscarriage. Cochrane Database of Systematic Reviews. Is 2. Art. No.: CD004073. doi 10.1002/14651858.CD004073.pub2.

9. Saffery R, Ellis J, Morley R. 2009. A convergent model for placental dysfunction encompassing combined suboptimal one-carbon donor and vitamin D bioavailability. Med Hypotheses. 73; 6: 1023—1028. https://doi.org/10.1016/j.mehy.2009.03.057; PMid:19819084

10. Smith AD, Kim YI, Refsum H. 2008. Is folic acid good for everyone? Am J Clin Nutr. 87; 3: 517—533. PMid:18326588

11. Teratology society position paper: recommendations for vitamin A use during pregnancy // Teratology. 2003. 35; 2: 269—275.

12. Burne TH, Becker A, Brown J et al. 2004. Transient prenatal vitamin D deficiency is associated with hyperlocomotion in adult rats. Behav Brain Res. 154; 2: 549—555. https://doi.org/10.1016/j.bbr.2004.03.023; PMid:15313044

13. Halicioglu O, Sutcuoglu S, Koc F et al. 2011, Dec 20. Vitamin B12 and folate statuses are associated with diet in pregnant women, but not with anthropometric measurements in term newborns. J Matern Fetal Neonatal Med.