• Manifest iron deficiency in pregnant women: estimation of Doppler blood flow parameters and ferrokinetic indicators during treatment

Manifest iron deficiency in pregnant women: estimation of Doppler blood flow parameters and ferrokinetic indicators during treatment

HEALTH OF WOMAN. 2017.4(120):62–68

Burlev V. A., Fedorova Yu. V., Sokur T. N., Ilyasova N. A.
Scientific Center of Obstetrics, Gynecology and Perinatology Acad. IN AND. Kulakov, Moscow
«Russian Bulletin of the Obstetrician-Gynecologist» 6, 2011

Ferrokinetic indicators and Doppler maternal-placental (MP) and fetoplacental blood flow parameters were studied in 36 pregnant women with mild manifest iron deficiency (MID) without baseline MP impairment and in 20 pregnant women with MID of the same degree and without baseline MP impairment. All the pregnant women were divided into 2 subgroups according to the therapy option for MID: those receiving an iron-containing drug and those taking this drug and a flavonoid. Combination therapy with an iron-containing agent and a flavonoid contributed to a statistically significant increase in hematological and ferrokinetc indicators, to the disappearance of the symptoms of anemic or sideropenic syndrome, to positive changes in MP blood flow velocities, and to increases in neonatal weight and height.

Key words: pregnancy, manifest iron deficiency, combination therapy.

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