• Etiopathogenetical aspects of I trimester pregnancy course in women after assisted reproductive technology

Etiopathogenetical aspects of I trimester pregnancy course in women after assisted reproductive technology

HEALTH OF WOMAN. 2017.4(120):98–101; doi 10.15574/HW.2017.120.98

Vygivska L. M., Nykoniuk T. R.
A.A. Bogomolets National Medical University, Kiev

The objective: to study etiopathogenetical aspects of pregnancy after IVF in women with a history of infertility.

Patients and methods. A prospective comprehensive survey of 220 pregnant in the first trimester of pregnancy after IVF with infertility of different genesis in history and 50 naturally firstly pregnant women.

Results. Etiopathogenetical factors of complications of pregnancy and reproductive losses in women after IVF in the first trimester of pregnancy were defined, including the leading role played by the age of pregnant women over 27 years, burdened obstetric and gynecological history, a long period of infertility, the imbalance of steroid hormones and the development of OHSS, consequences carried inflammatory processes and surgery on the pelvic organs.

Conclusion. First trimester of pregnancy is most dangerous for developing of complications of pregnancy and reproductive losses for women after ART regardless of etiologic factors of infertility in history, and involves optimization and implementation of comprehensive diagnostic and treatment and preventive measures.

Key words: infertility, pregnancy, assisted reproductive technology.

REFERENCES

1. Adamov MM. 2011. Vahitnist i polohy pislia zastosuvannia dopomizhnykh reproduktyvnykh tekhnolohii, vykonanykh za vidsutnosti ta naiavnosti matkovykh trub. Zdorove zhenshchynу 5:159–160.

2. Aleksandrova NV, Baev OR, Ivanets TYu. 2012. Prezhdevremennyie rodyi pri beremennosti, nastupivshey s ispolzovaniem vspomogatelnyih reproduktivnyih tehnologiy. Puti profilaktiki. Akusherstvo i ginekologiya 4–2:33–38.

3. Besplodnyiy brak: prakticheskoe rukovodstvo. pod red. chl.-kor. NAMN Ukrainyi, prof. VK Chayki. Donetsk: ChP «Lavis». 2012:384.

4. Vyhivska LM, Nykoniuk TR, Kovaliuk TV, Lastovetska LD. 2016. Stan systemy hemostazu ta endotelialnoho statusu u vahitnykh pislia zastosuvannia DRT. Zbirnyk prats Asotsiatsii akusheriv-hinekolohiv Ukrainy 2(38):109–114.

5. Hryshchenko MH. 2011. Patohenetychni osnovy vdoskonalennia dopomizhnykh reproduktyvnykh tekhnolohii u zhinok, yaki perenesly khronichni zapalni zakhvoriuvannia orhaniv maloho taza. Avtoref. dys. d-ra med. nauk: spets. 14.01.01 «Akusherstvo ta hinekolohiia». Kharkivskyi natsionalnyi medychnyi universytet. Kh:34.

6. Dopomizhni reproduktyvni tekhnolohii likuvannia bezpliddia: navchalnyi posibnyk. Za red. FV Dakhna, VV Kaminskoho, OM Yuzka. K. 2011:338.

7. Kulakov VI, Leonov BV, Kuzmichev LI. 2008. Lechenie zhenskogo i muzhskogo besplodiya. Vspomogatelnyie reproduktivnyie tehnologii. M, MIA:592.

8. Levkovich MA, Linde VA, Andreeva VO. 2012. Narushenie immunnogo gomeostaza pri ugroze preryivaniya beremennosti infektsionnogo geneza. Tavricheskiy mediko-biologicheskiy vestnik 15;2 (2):313.

9. Mozghova OM. 2005. Kompleksna diahnostyka ryzyku ta poperedzhennia zahrozy pereryvannia vahitnosti u zhinok pislia ekstrakorporalnoho zaplidnennia. Ukrainskyi Medychnyi Chasopys 2:102–109.

10. Ferraretti AP, Goossens V, de Mouzon J, Bhattacharya S, Castilla JA, Korsak V et al. 2012. Assisted reproductive technology in Europe, 2008: results generated from European registers by ESHRE. Hum Reprod. 27:2571–84. https://doi.org/10.1093/humrep/des255; PMid:22786779

11. Ford HB, Schust DJ. 2009. Recurrent pregnancy loss: etiology, diagnosis, and therapy. Reviews in Obstetrics and Gynecology 2;2:76–83. PMid:19609401 PMCid:PMC2709325

12. Nyboe Andersen A, Popovic-Todorovic B, Schmidt KT. 2002. Progesterone supplementation during early gestations after IVF or ICSI has no effect on the delivery rates: a randomized controlled trial. Human Reproduction 17;2:357–361. https://doi.org/10.1093/humrep/17.2.357

13. De Cat AC, Yarde F, Gremmels H et al. 2013. Serum AMH levels and circulating progenitor cells in women; the role of vascular function in ovarian aging. Human Reproduction 28;1:28–29.

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