• Echographic monitoring of placental mesenchymal dysplasia

Echographic monitoring of placental mesenchymal dysplasia

PERINATOLOGIYA I PEDIATRIYA. 2017.2(70):80-83; doi 10.15574/PP.2017.70.80

Volyk N. K.
Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of placenta, with an echographic pattern similar to a hydatidiform mole in the form of a placentomegaly with multiple cystic lesions. The case of diagnosed PMD in the second trimester with a normal pregnancy outcome is reported. The dynamics of the echographic pattern during pregnancy is presented, and the differential-diagnostic series and prognosis of pregnancy are discussed. When making a differential diagnosis of cystic changes in the placenta detected with ultrasound, the physisian should remember about a rare pathology as placental mesenchymal dysplasia, which featured the absence of high_speed signals of blood flow inside the affected area and a normally appearing fetus.

Key words: ultrasonography, Doppler ultrasound, placental mesenchymal dysplasia, differential diagnosis


1. Chen CP. (2007). Syndromes and disorders associated with omphalocele (I): Beckwith-Wiedemann syndrome. Taiwan J Obstet Gynecol. 46; 2: 96—102. https://doi.org/10.1016/S1028-4559(07)60002-3; https://doi.org/10.1016/S1028-4559(07)60003-5

2. Maher ER, Reik W. (2000). Beckwith-Wiedemann syndrome:imprinting in clusters revisited. J Clin Invest. 105; 3: 247—252. https://doi.org/10.1172/JCI9340; PMid:10675349 PMCid:PMC517490

3. Moscoso G, Jauniaux E, Huston J. (1991). Placental vascular anomaly with diffuse mesenchymal stem villous hyperplasia: new clinico-pathological entity? Pathol Res Pract. 187: 324—8. https://doi.org/10.1016/S0344-0338(11)80791-0

4. Cohen MC, Roper KC, Sebire NJ et al. (2005). Placental mesenchymal dysplasia associated with fetal aneuploidy. Prenat Diagn. 25; 3: 187—192. https://doi.org/10.1002/pd.1103; PMid:15791673

5. Matsui H, Iitsuka Y, Yamazawa K et al. (2003). Placental mesenchymal dysplasia initially diagnosed as partial mole. Pathol Int. 53: 810—3. https://doi.org/10.1046/j.1440-1827.2003.01550.x; PMid:14629309

6. Paradinas FJ, Sebire NJ, Fisher RA et al. (2001). Pseudo-partial moles:placental stem vessel hydrops and the association with Beckwith-Wiedemann syndrome and complete moles. Histopathology. 39: 447—54. https://doi.org/10.1046/j.1365-2559.2001.01256.x; PMid:11737301

7. Reinhart RD, Wells WA, Harris RD. (1999). Focal aneurysmal dilatation of subchorionic vessels simulating chorioangioma. Ultrasound Obstet Gynecol. 13: 147—149. https://doi.org/10.1046/j.1469-0705.1999.13020147.x; PMid:10079497

8. Nayeri UA, West AB, Grosseta HK et al. (2013). Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41: 366—374. https://doi.org/10.1002/uog.12359; PMid:23239538

9. Kaido Y, Kikuchi A, Kanasugi T et al. (2014). Unusual markedly-dilated chorionic vessels with placentomegaly. SpringerPlus. 3: 146. https://doi.org/10.1186/2193-1801-3-146; PMid:25674446 PMCid:PMC4320145

10. Wee L, Jauniaux E. (2005). Prenatal diagnosis and management of twin pregnancies complicated by a co-existing molar pregnancy. Prenat Diagn. 25: 772—6. https://doi.org/10.1002/pd.1272; PMid:16170836

Содержание журнала Full text of article