• Discussion of new approach to the management of polycystic ovary syndrome

Discussion of new approach to the management of polycystic ovary syndrome

HEALTH OF WOMAN. 2017.6(122):45–48; doi 10.15574/HW.2017.122.45

Doubossarskaya Z. M.
SI «Dnipropetrovsk medical Academy of MH of Ukraine»

The objective: Critical evaluation of modern therapeutic methods for polycystic ovary syndrome (POS); depending of reproductive plans for infertility therapy needed or removing of cosmetic issues by including Protalis to complex therapy program.

Patients and methods. 40 women in the age from 27 to 37; with confirmed diagnosis of POS according to criteria of Rotterdam consensus were examined. They were divided to 2 subgroups; first (30) got traditional therapy with individual variations: laparoscopic drilling of ovaries, Metphormin, lifestyle modification and Protalis. Second group got their therapy without Protalis. Every 3, 6, 9, 12 months clinical, hormonal manifestations of POS were controlled.

Results. Usage of complex therapy of POS with Protalis facilitated statistically unreliable lowering of BMI; but number of women with irregular menstrual periods increased in 3.4 times; restoration of reproductive function were happened in 26.6 % cases (10% without Protalis). This therapy facilitated diminishing of cosmetic issues, better skin conditions. Diminishing of acne, lowering of hirsute number and with complex approach to reproductive health they got better life quality.

Conclusions. Practicing gynecologists after the studies of several etiological hypotheses about POS, realized that syndrome is a defect of not only one gene but it is polygenic and it is explain phenotype of patients and all variations depending of a type of metabolic disorders. Life style changes (diet and exercises) are cornerstone of management of patients with POS with high body mass and obesity (particularly abdominal) and they can lower many symptoms of POS? considering effectiveness of usage of Protalis in the complex therapy of POS in our study and in documented foreign studies it can be recommended in usage in clinical practice.

Key words: polycystic ovary syndrome, chronic anovulation, hyperandrogeny, Protalis.

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