• Congenital hypothyroidism in children: the intellectual development and psychosocial adaptation

Congenital hypothyroidism in children: the intellectual development and psychosocial adaptation

SOVREMENNAYA PEDIATRIYA.2017.4(84):107-111; doi 10.15574/SP.2017.84.107

Sorokman T. V., Popeliuk N. O.
Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi

Objective — to estimate the degree of intellectual development and psychosocial adaptation of children with congenital hypothyroidism (CH).

Materials and methods. There were examined 22 patients with CH aged from 1 month to 15 years. The evaluation of the results of such methods as ultrasonography, EEG, hormone panel, logopaedic and audiologic examination, assessment of intelligence (Wechsler Intelligence Scale for Children) and individual peculiarities of personality (Children's drawing test) was performed. Statistical analysis was conducted using the software Statistica 6.0.

Results. In 38.1% of patients, the nodular formations of thyroid gland were diagnosed. The positive correlation between the age and the presence of nodular formations (r=0,76; p<0,001) was observed. The TSH median on the first stage screening was 38 mkU/L. The vT4 level ranged from 0.49 to 14.7 pmol/l. Audiological examination revealed the diminished hearing in 43.8%, the logopaedic one showed the general delay or retardation in early language in 36.3% of cases. The average IQ of children with CH was on the lower limit of normal and made up 88.9±1.52 points. General IQ depended on the capacity of the shortterm memory (r=0.6; p<0.05). Besides, it was significantly lower in children with the declined processes of memorization (103.2±9.6 points). In 45.4% of cases, the functional changes of diencephalic areas of the cerebral cortex were observed. The most common psychological parameters in children with CH appeared depression (p<0,05), aggression and anxiety were almost equifrequent.

Conclusion. The children with CH have different health deviations, such as nodal formations in thyroid gland, diminished hearing, delay or retardation in early language development and functional changes in the electrical activity of cerebral cortex. The general IQ in most children with CH is within the normal range in the case of timely treatment.

Key words: children, congenital hypothyroidism, intellectual development, psychosocial adaptation.


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