• Clinical manifestations of reproductive health and life quality in fertile age women with subclinical hypothyroidism in conditions of comorbidity

Clinical manifestations of reproductive health and life quality in fertile age women with subclinical hypothyroidism in conditions of comorbidity

HEALTH OF WOMAN. 2017.5(121):54–56; doi 10.15574/HW.2017.121.54

Varchenko  L. M.
Kyiv City Clinical Endocrinology Center

The objective: to evaluate the clinical manifestations of reproductive health and quality of life (QOL) disorders in women of reproductive age with high comorbidity against subclinical hypothyroidism (SHT) and manifest hypothyroidism (MHT).

Materials and methods. 113 cases of SHT (1st group) and 65 cases of MHT (2 nd group) in women of reproductive age were analyzed. The diagnosis of hypothyroidism is established on the basis of data of anamnesis, physical examination, ultrasound of the thyroid gland and determination of thyroid-stimulating hormone levels and free thyroxine in the blood by electroluminescence.

Results. Assessment of QoL using the MOS SF-36 questionnaire was performed in women of reproductive age with SHT, with a high (61.9%) level of menstrual irregularities, gynecological (74.3%) and extragenital (82.3%) diseases, which indicates High comorbidity. It was revealed mainly the average values of QoL on almost all scales, except for emotional functioning.

In women with MHT, with extremely high comorbidity (in 100% of cases), the QL values were reduced and only on the scale of "pain" – within the average.

The conclusion. The data obtained make it possible to recommend the definition of quality of life indicators in women of reproductive age with subclinical hypothyroidism in the practice of a gynecologist as an integral characteristic of health.

Key words: subclinical hypothyroidism, menstrual irregularities, comorbid conditions, quality of life, MOS SF-36 questionnaire, integral health indicators.

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