• Cholestatic hepatosis in pregnant women: obstetrical and therapeutic approaches 

Cholestatic hepatosis in pregnant women: obstetrical and therapeutic approaches 

PERINATOLOGIYA I PEDIATRIYA.2016.1(65):37-41;doi 10.15574/PP.2016.65.37 
 

Cholestatic hepatosis in pregnant women: obstetrical and therapeutic approaches 
 

Davidova Yu. V., Limanskaya A. Yu., Mokrik A. N.

SI «Institute of Pediatrics, Obstetrics and Gynecology NAMS of Ukraine», Kiev 
 

Objective — to study the effectiveness and safety of the use of Ursonost preparation of Organosin Company, produced by Francia Farmaceutici Industria Farmaco Biologica S.r.l. (Italy)) in pregnant women with cholestatic hepatosis. 
 

Patients and methods. A total of 42 pregnant women, who were under outpatient and inpatient treatment in the department of obstetric problems of extragenital pathology for the period of 2013–2015 years were comprehensively examined. All pregnant at the time of observation were at the end of the II and III trimester of pregnancy. All 42 pregnant were divided into three groups. 
 

Results. For the end of the treatment by Ursonost preparation in the first and second group of pregnant was marked a general improvement of well-being such as reduction of fatigue, weakness, dyspepsia and pruritus. Also, was noted a normalization of blood biochemical parameters. 
 

Conclusions. As a result of the inclusion of Ursonost preparation of Organosin Company, produced by Francia Farmaceutici Industria Farmaco Biologica S.r.l. (Italy)) was observed a significant improvement in overall well-being and normalization of blood biochemical parameters in women of the first and second test groups. Application of the proposed medical complex in the present groups of pregnant women allowed to seize the results of the pregnancy outcomes and almost avoiding premature delivery. Effectiveness and safety of the use of preparation during the pregnancy allow recommend inclusion of Ursonost preparation of Organosin Company, produced by Francia Farmaceutici Industria Farmaco Biologica S.r.l. (Italy)) to the treatment regimen of cholestatic hepatosis in pregnant. 
 

Key words: pregnancy, cholestatic hepatosis in pregnant, Ursonost. 
 

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