• Atherogenic predictive markers of preeclampsia (Analytical review of literature and own observations)

Atherogenic predictive markers of preeclampsia (Analytical review of literature and own observations)

HEALTH OF WOMAN. 2017.6(122):140–143; doi 10.15574/HW.2017.122.140

Aksonova A. V.
A.A. Bogomolets National Medical University, Kiev

The article analyzes the data of domestic and foreign scientific publications of modern aspects of prediction of preeclampsia based on the study of atherogenic markers and their possible role in the formation of this complication in pregnancy. With the help of ROC-analysis and binary logistic regression, the reliability of atherogenic markers was statistically proved and a personalized assessment of the probability of the pathology development was made, taking into account the deviations of clinical indices relative to threshold estimates.

Key words: pre-eclampsia, atherogenic markers, prognosis, lipid metabolism, dyslipidemia, ROC-analysis, binary logistic regression.

REFERENCES

1. Bahtina TP, Kovalev VV. 2013. Harakteristika lipidnogo obmena i perekisnogo okisleniya lipidov u beremennyih s preeklampsiey razlichnoy stepeni tyazhesti. Sibirskiy meditsinskiy zhurnal 6:73–76.

2. Ventskivska IB, Aksonova AV, Yuzvenko TIu. 2016. Rol pokaznykiv lipidohramy protiahom vahitnosti v prohnozuvanni ryzyku rozvytku preeklampsii. Mizhnarodnyi endokrynolohichnyi zhurnal (International journal of endocrinology) 5(77):51–55.

3. Grischenko OV, Storchak AV, Toan Buy Son. 2011. Rol matriksa soedinitelnoy tkani v obespechenii funktsionalnoy aktivnosti endoteliya u beremennyih. Reproduktivnaya endokrinologiya 1:36–41.

4. Dzherieva IS, Volkova NI. 2010. Arterialnaya gipertenziya i metabolicheskie narusheniya. Klinicheskaya meditsina 88(2):4–8.

5. Ivanov II, Cheripko MV, Kosolapova NV, Prochan EN. 2012. Preeklampsiya beremennyih: osobennosti patogeneza, taktiki vedeniya. Tavricheskiy mediko-biologicheskiy vestnik 15;2;2 (58):273–286.

6. Ventskivska IB, Aksonova AV, Yuzvenko TIu. Aterohenni pokaznyky ta kardialni indeksy v prohnozuvanni rozvytku preeklampsii ta yii kardiometabolichnykh naslidkiv. EUREKA, Health Sciences 6 (November): 30–36.

7. Mavzyutov AR, Bondarenko KR, Enikeev AN, Bondarenko VM. 2012. Sistemnaya endotoksemiya kak patogeneticheskiy faktor oslozhneniya beremennosti. Zhurnal mikrobiologii 5:16–21.

8. Marychereda VH. 2011. Analiz suchasnykh i perspektyvnykh biomarkeriv preeklampsii (Ohliad literatury i vlasni dani. Chastyna. I, II). Pediatriia, akusherstvo ta hinekolohiia 5:79–85.

9. Marichereda VG. 2011. Rol dislipidemii v razvitii preeklampsii. Zdorove zhenschinyi 7:121–123.

10. Mutsalhanova YuS. 2015. Prognosticheskie markeryi preeklampsii. Sovremennyie problemyi nauki i obrazovaniya 5:326.

11. Nevidkladni stany v akusherstvi: pidruchnyk dlia studentiv. Za red. prof. BM Ventskivskoho, AIa Senchuk, OO Zelinskoho. K, «Zdorovia materi i dytyny». 2013:5–7.

12. Perepelitsa SA, Sednev OV. 2015. Patogeneticheskaya rol narusheniya obmena holesterina i triglitseridov v razvitii kriticheskih sostoyaniy. Obschaya reanimatologiya 11;5:67–74.

13. Saveleva GM i soavt. 2010. Eklampsiya v sovremennom akusherstve. Akusherstvo i ginekologiya 6:4–9.

14. Serov VN, Vetrov VV, Voinov VA. 2011. Preeklampsiya. S.Peterburg:250.

15. Hvorik NV, Tsyirkunov VM. 2012. Lipidnyiy distress-sindrom pri beremennosti, oslozhnennoy narusheniem funktsii pecheni. Zdravoohranenie 4:4–9.

16. Atherosclerosis, American Association of Clinical Endocrinologists Task Force for Management of Dyslipidemia and Prevention of. American Association of Clinical Endocrinologists’ Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis.Endocrine Practise 18(1). 2012.

17. Bellamy L, Casas JP, Hingorani AD, Williams DJ. 2007. Pre-eclampsia andrisk of cardiovascular disease and cancer in later life: systematic reviewand meta-analysis. BMJ. 335:974. https://doi.org/10.1136/bmj.39335.385301.BE; PMid:17975258 PMCid:PMC2072042

18. Belo L, Santos-Silva A, Quintanilha A, Rebelo I. 2008. Similarities between pre-eclampsia and atherosclerosis: a protective effect of physical exercise? Curr Med Chem. 15(22):2223–9. https://doi.org/10.2174/092986708785747553; PMid:18781945

19. Brown MC, Best KE, Pearce MS, Waugh J, Robson SC, Bell R. 2013, Jan. Cardiovascular disease risk in women with pre-eclampsia: systematic review and meta-analysis. European journal of epidemiology 28(1):1–19. https://doi.org/10.1007/s10654-013-9762-6; PMid:23397514

20. Bryant EK, Dressen AS, Bunker CH et al. 2013. A Multiethnic Replication Study of Plasma Lipoprotein Levels-Associated SNPs Identified in Recent GWAS. PloS one. 8(5):e63469. https://doi.org/10.1371/journal.pone.0063469; PMid:23717430 PMCid:PMC3661596

21. Bukan N, Kandemir O, Nas T, Gulbahar O, Unal A, Cayci B. 2012, Jul. Maternal cardiac risks in pre-eclamptic patients. The journal of maternal-fetal & neonatal medicine: the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceani a Perinatal Societies, the International Society of Perinatal Obstet. 25(7):912–914.

22. Buurma AJ, Turner RJ, Driessen JH, et al. 2013, Jan 8.  Genetic variants in preeclampsia: a meta-analysis. Human reproduction update. https://doi.org/10.1093/humupd/dms060

23. Camille E Powe, Richard J Levine and S Ananth Karumanchi. 2011. Preeclampsia, a Disease of the Maternal Endothelium. The Role of Antiangiogenic Factors and Implications for Later Cardiovascular Disease. Circulation. 123:2856–2869. https://doi.org/10.1161/CIRCULATIONAHA.109.853127; PMid:21690502 PMCid:PMC3148781

24. Cassandra N, SmithCaitlin J, SaftlasAudrey F, RobinsonJennifer G, RyckmanKelli K. 2014, Aug 15. Maternal Hyperlipidemia and the Risk of Preeclampsia: a Meta-Analysis. Am J Epidemiol. 180(4):346–358. https://doi.org/10.1093/aje/kwu145; PMid:24989239 PMCid:PMC4565654

25. Charlton F, Tooher J, Rye KA, Hennessy A. 2014, Mar. Cardiovascular risk, lipids and pregnancy: preeclampsia and the risk of later life cardiovascular disease. Heart Lung Circ. 23(3):203–12. https://doi.org/10.1016/j.hlc.2013.10.087; PMid:24268601

26. Demirci Oya. 2011, October. Serum lipids level assessed in early pregnancy and risk of preeclampsia. J.Obstet. Gynaecol. Res. 37;10:1427–1432. https://doi.org/10.1111/j.1447-0756.2011.01562.x; PMid:21676073

27. Ekhator CN, Ebomoyi MI. 2012, May. Blood glucose and serum lipid profiles during pregnancy. African journal of diabetes medicine. 20;1:16–19.

28. El-Nakhal Samar. 2015. Case-control study of risk factors associated withpreeclampsia in the Gaza Strip. Journal of Medicine and Medical Sciences. 6(9):229–233.

29. Ghulmiyyah L, Sibai B. 2012, Feb. Maternal mortality from preeclampsia/eclampsia. Seminars in perinatology 36(1):56–59. https://doi.org/10.1053/j.semperi.2011.09.011; PMid:22280867

30. Goldberg AS, Hegele RA. 2012. Severe hypertriglyceridemia in pregnancy. J Clin Endocrinol Metab 97:2589–96. https://doi.org/10.1210/jc.2012-1250; PMid:22639290

31. Hooijschuur MC, Ghossein-Doha C, Al-Nasiry S, Spaanderman ME. 2015, Sep. Maternal metabolic syndrome, preeclampsia, and small for gestational age infancy. Am J Obstet Gynecol. 213(3):370.e1-7. https://doi.org/10.1016/j.ajog.2015.05.045; PMid:26008179

32. Kalar Musleh Uddin, Kalar Nabila, Mansoor Farah, Rehman Malik Abdul, Lessley Todd, Kreimer Susanne, Abbasi Ayesha, Bilal Muhammad. 2012. Preeclampsia and Lipid levels – a case control study. International Journal of Collaborative Research on Internal Medicine & Public Health 4;10:1738–1745.

33. Kaloti Amandeep Singh, Kaur Charanjeet, Goel RK et al. 2013, April. Study of lipid profile trendsin in woman of pregnancy induced hypertension on cases in a rural set up. Journal of evolution of medical and dental sciences. 2; 13:1:2024–2031.

34. Kashinakunti SV, Sunitha H, Gurupadappa K, Manjula R. 2010. Lipid Profile In Preeclampsia – A Case Control Study. Journal of Clinical and Diagnostic Research (4):2748–51.

35. Khalil A, Cowans NJ. 2010. First-trimester markers for the prediction of pre-eclampsia in woman with a-priori high risk. Ultrasound Obstet Gynecol 35:671–679. PMid:20069559

36. Lima VJ, Andrade CR, Ruschi GE et al. 2011. Serum lipid levels in pregnancies complicated by preeclampsia. Sao Paulo Med J. 129(2):73–6. https://doi.org/10.1590/S1516-31802011000200004; PMid:21603783

37. Mittal Meena, Kulkarni CV, Panchonia Ashok, Mittal RK. 2014. Evaluation of serum lipid profile in cases of preeclampsia and eclampsia. Int J Reprod Contracept Obstet Gynecol. 3(3):732-734.

38. Mittal Meena, Kulkarni CV, Panchonia Ashok, Mittal RK. 2014. Evaluation of serum lipid profile in cases of preeclampsia and eclampsia. Int J Reprod Contracept Obstet Gynecol. 3(3):732-734.

39. Niromanesh S, Shirazi M, Dastgerdy E, Sharbaf FR, Shirazi M, Khazaeipour Z. 2012, Sep-Oct. Association of hypertriglyceridaemia with preeclampsia, preterm birth, gestational diabetes and uterine artery pulsatility index. The National medical journal of India. 25(5):265–267. PMid:23448624

40. Palinski Wulf. 2014. Effect of Maternal Cardiovascular Conditions and Risk Factors on Offspring Cardiovascular Disease. Circulation. 129:2066–2077. https://doi.org/10.1161/CIRCULATIONAHA.113.001805; PMid:24842934 PMCid:PMC4053195

41. Poon LC, Nicolaides KH. 2014. Early prediction of preeclampsia. Obstet Gynecol Int. 2014:297-397. https://doi.org/10.1155/2014/297397; PMid:25136369 PMCid:PMC4127237

42. Preeclampsia Foundation. 2010. Available at: www.preeclampsia.org

43. Raymond D, Peterson E. 2011, Aug. A critical review of early-onset and late-onsetpreeclampsia. Obstetrical & gynecological survey. 66(8):497–506. https://doi.org/10.1097/OGX.0b013e3182331028; PMid:22018452

44. Saxena AR, Karumanchi SA, Brown NJ, Royle CM, McElrath TF, Seely EW. 2010. Increased sensitivity to angiotensin II is present postpartum in women with a history of hypertensive pregnancy. Hypertension 55:1239–1245. https://doi.org/10.1161/HYPERTENSIONAHA.109.147595; PMid:20308605 PMCid:PMC2880505

45. Teslovich TM, Musunuru K, Smith AV et al. 2010, Aug 5. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 466(7307):707–713. https://doi.org/10.1038/nature09270; PMid:20686565 PMCid:PMC3039276

46. Townsend Rosemary, O’Brien Patrick, Khalil Asma. 2016. Current best practice in the management of hypertensive disorders in pregnancy. Integr. Blood Press Control. 9:79–94. https://doi.org/10.2147/IBPC.S77344; PMid:27555797 PMCid:PMC4968992

47. Vani L, Gayathri A et al. 2015. Lipid profile parameters in normal and preeclampsia complicating pregnancies-A prospective observational study. The Ame J Sci et Med Res. 1(1):61–66. https://doi.org/10.17812/ajsmr2015114

48. Wiznitzer A, Mayer A, Novack V et al. 2009, Nov. Association of lipid levels during gestation with preeclampsia and gestational diabetes mellitus: a population-based study. American journal of obstetrics and gynecology 201(5):482e 481–488.